Frank Bernhard - Publications, H-index & Citations

Frank Bernhard

university hospital tübingen

49H指数

197论文数

6.8K被引数

收录论文 56

发表时间

Targeted Inhibition of ELANE Expression Using Adenine Base Editing to Treat Severe Congenital Neutropenia 利用腺嘌呤碱基编辑靶向抑制ELANE表达以治疗重症先天性中性粒细胞减少症

Molecular Therapy Methods & Clinical Development

IF4.7

2025-11-05

OAAI

Betül Findik; Benjamin Dannenmann; Franka Bernhard; Masako Monika Kaufmann; Sandra Ammann; Sergey Kandabarau; Maksim Klimiankou; Fabian Mauch; Patrick Münzer; Oliver Borst; Isabel Klefenz; Doris Steinemann; Claudia Lengerke; Cornelia Zeidler; Toni Cathomen; Karl Welte; Masoud Nasri; Julia Skokowa

Cryo-EM structure of a cell-free synthesized full-length human β1-adrenergic receptor in complex with Gs 人源全长β1-肾上腺素能受体在细胞自由合成条件下的Cryo-EM结构，与Gs蛋白复合物

Structure

IF4.3

2025-08-25

OAAI

Felipe Merino; Zoe Köck; Utz Ermel; Philipp Dahlhaus; Anna Grimm; Anja Seybert; Jan Kubicek; Achilleas S. Frangakis; Volker Dötsch; Daniel Hilger; Frank Bernhard

Transporter function characterization via continuous-exchange cell-free synthesis and solid supported membrane-based electrophysiology

BIOELECTROCHEMISTRY

IF4.5

2024-10-01

OAAI

Dong, Fang; Lojko, Pawel; Bazzone, Andre; Bernhard, Frank; Borodina, Irina

Cryo-EM structure of cell-free synthesized human histamine 2 receptor/Gs complex in nanodisc environment

NATURE COMMUNICATIONS

IF15.7

2024-02-28

OAAI

Koeck, Zoe; Schnelle, Kilian; Persechino, Margherita; Umbach, Simon; Schihada, Hannes; Januliene, Dovile; Parey, Kristian; Pockes, Steffen; Kolb, Peter; Doetsch, Volker; Moeller, Arne; Hilger, Daniel; Bernhard, Frank

Electroneutral Polymer Nanodiscs Enable Interference-Free Probing of Membrane Proteins in a Lipid-Bilayer Environment

SMALL

IF12.1

2022-10-13

OAAI

Glueck, David; Grethen, Anne; Das, Manabendra; Mmeka, Ogochukwu Patricia; Patallo, Eugenio Perez; Meister, Annette; Rajender, Ritu; Kins, Stefan; Raeschle, Markus; Victor, Julian; Chu, Ci; Etzkorn, Manuel; Koeck, Zoe; Bernhard, Frank; Babalola, Jonathan Oyebamiji; Vargas, Carolyn; Keller, Sandro

Membrane insertion mechanism and molecular assembly of the bacteriophage lysis toxin φX174-E

FEBS JOURNAL

IF4.2

2020-12-12

OAAI

Mezhyrova, Julija; Martin, Janosch; Peetz, Oliver; Doetsch, Volker; Morgner, Nina; Ma, Yi; Bernhard, Frank

The Conformational Equilibrium of the Neuropeptide Y2 Receptor in Bilayer Membranes

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2020-09-30

OAAI

Krug, Ulrike; Gloge, Anika; Schmidt, Peter; Becker-Baldus, Johanna; Bernhard, Frank; Kaiser, Anette; Montag, Cindy; Gauglitz, Marcel; Vishnivetskiy, Sergey A.; Gurevich, Vsevolod V.; Beck-Sickinger, Annette G.; Glaubitz, Clemens; Huster, Daniel

Rat Organic Cation Transporter 1 Contains Three Binding Sites for Substrate 1-Methyl-4-phenylpyridinium per Monomer

MOLECULAR PHARMACOLOGY

IF3

2019-02-01

OAAI

Keller, Thorsten; Gorboulev, Valentin; Mueller, Thomas D.; Doetsch, Volker; Bernhard, Frank; Koepsell, Hermann

Structural and functional insights into the interaction and targeting hub TMD0 of the polypeptide transporter TAPL

SCIENTIFIC REPORTS

IF3.9

2018-10-23

OAAI

Bock, Christoph; Loehr, Frank; Tumulka, Franz; Reichel, Katrin; Wuerz, Julia; Hummer, Gerhard; Schaefer, Lars; Tampe, Robert; Joseph, Benesh; Bernhard, Frank; Doetsch, Volker; Abele, Rupert

LILBID and nESI: Different Native Mass Spectrometry Techniques as Tools in Structural Biology

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

IF2.7

2018-09-17

OAAI

Peetz, Oliver; Hellwig, Nils; Henrich, Erik; Mezhyrova, Julija; Doetsch, Volker; Bernhard, Frank; Morgner, Nina

Systematic optimization of cell-free synthesized human endothelin B receptor folding

METHODS

IF4.3

2018-09-01

PREAI

Rues, Ralf-Bernhardt; Dong, Fang; Doetsch, Volker; Bernhard, Frank

Precursor-Based Selective Methyl Labeling of Cell-Free Synthesized Proteins

ACS CHEMICAL BIOLOGY

IF3.8

2018-06-12

PREAI

Lazarova, Mariya; Loehr, Frank; Rues, Ralf-Bernhardt; Kleebach, Robin; Doetsch, Volker; Bernhard, Frank

Protein labeling strategies for liquid-state NMR spectroscopy using cell-free synthesis 使用无细胞合成的液态NMR光谱的蛋白质标记策略

Progress in Nuclear Magnetic Resonance Spectroscopy

IF8.2

2018-04-01

PREAI

Hoffmann, Beate; Loehr, Frank; Laguerre, Aisha; Bernhard, Frank; Doetsch, Volker

Insights into Cotranslational Membrane Protein Insertion by Combined LILBID-Mass Spectrometry and NMR Spectroscopy

ANALYTICAL CHEMISTRY

IF6.7

2017-10-30

PREAI

Peetz, Oliver; Henrich, Erik; Laguerre, Aisha; Loehr, Frank; Hein, Christopher; Doetsch, Volker; Bernhard, Frank; Morgner, Nina

From Gene to Function: Cell-Free Electrophysiological and Optical Analysis of Ion Pumps in Nanodiscs

BIOPHYSICAL JOURNAL

IF3.1

2017-09-01

OAAI

Henrich, Erik; Soermann, Janina; Eberhardt, Peter; Peetz, Oliver; Mezhyrova, Julija; Morgner, Nina; Fendler, Klaus; Doetsch, Volker; Wachtveitl, Josef; Bernhard, Frank; Bamann, Christian

Integral Membrane Proteins Can Be Crystallized Directly from Nanodiscs

CRYSTAL GROWTH & DESIGN

IF3.4

2017-01-25

OAAI

Nikolaev, M.; Round, E.; Gushchin, I.; Polovinkin, V.; Balandin, T.; Kuzmichev, P.; Shewhenko, V.; Borshchevskiy, V.; Kuklin, A.; Round, A.; Bernhard, F.; Willbold, D.; Biildt, G.; Gordeliy, V.

Analyzing native membrane protein assembly in nanodiscs by combined non-covalent mass spectrometry and synthetic biology

ELIFE

IF0

2017-01-09

OAAI

Henrich, Erik; Peetz, Oliver; Hein, Christopher; Laguerre, Aisha; Hoffmann, Beate; Hoffmann, Jan; Doetsch, Volker; Berhard, Frank; Morgner, Nini

Lipid Requirements for the Enzymatic Activity of MraY Translocases and in Vitro Reconstitution of the Lipid II Synthesis Pathway

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2016-01-01

OAAI

Henrich, Erik; Ma, Yi; Engels, Ina; Muench, Daniela; Otten, Christian; Schneider, Tanja; Henrichfreise, Beate; Sahl, Hans-Georg; Doetsch, Volker; Bernhard, Frank

Membrane protein production in Escherichia coli cell-free lysates 大肠杆菌无细胞裂解物中的膜蛋白生产

FEBS LETTERS

IF3

2015-05-01

OAAI

Henrich, Erik; Hein, Christopher; Doetsch, Volker; Bernhard, Frank

Rapid Activity Screening of Ion Channels Expressed in Cell-Free Systems Using a Lipid Bilayer Array Pcb-Device

BIOPHYSICAL JOURNAL

IF3.1

2015-01-01

OAAI

Zaitseva, Ekaterina; Baaken, Gerhard; Petersen, Soenke; Hein, Christopher; Bernhard, Frank; Beckler, Matthias; Kreir, Mohamed; George, Michael; Fertig, Niels; Rossi, Michele; Thei, Federico; Behrends, Jan C.

研究方向