Kadi L. Saar - Publications, H-index & Citations

Kadi L. Saar

University of Cambridge

22H指数

68论文数

1.7K被引数

收录论文 28

发表时间

Biomolecular condensates sustain pH gradients at equilibrium through charge neutralization 生物分子缩合物通过电荷中和维持平衡的pH梯度

Nature Chemistry

IF20.2

2026-01-29

OAAI

Hannes Ausserwöger; Rob Scrutton; Charlotte M. Fischer; Tomas Sneideris; Daoyuan Qian; Ella de Csilléry; Ieva Baronaite; Kadi L. Saar; Alan Z. Białek; Marc Oeller; Georg Krainer; Titus M. Franzmann; Sina Wittmann; Juan M. Iglesias-Artola; Gaetano Invernizzi; Anthony A. Hyman; Simon Alberti; Nikolai Lorenzen; Tuomas P. J. Knowles

Assessment of fine-tuned large language models for real-world chemistry and material science applications 评估用于现实世界化学和材料科学应用的微调大型语言模型

CHEMICAL SCIENCE

IF7.4

2025-01-01

OAAI

Van Herck, Joren; Gil, Maria Victoria; Jablonka, Kevin Maik; Abrudan, Alex; Anker, Andy S.; Asgari, Mehrdad; Blaiszik, Ben; Buffo, Antonio; Choudhury, Leander; Corminboeuf, Clemence; Daglar, Hilal; Elahi, Amir Mohammad; Foster, Ian T.; Garcia, Susana; Garvin, Matthew; Godin, Guillaume; Good, Lydia L.; Gu, Jianan; Xiao Hu, Noemie; Jin, Xin; Junkers, Tanja; Keskin, Seda; Knowles, Tuomas P. J.; Laplaza, Ruben; Lessona, Michele; Majumdar, Sauradeep; Mashhadimoslem, Hossein; Mcintosh, Ruaraidh D.; Moosavi, Seyed Mohamad; Mourino, Beatriz; Nerli, Francesca; Pevida, Covadonga; Poudineh, Neda; Rajabi-Kochi, Mahyar; Saar, Kadi L.; Hooriabad Saboor, Fahimeh; Sagharichiha, Morteza; Schmidt, K. J.; Shi, Jiale; Simone, Elena; Svatunek, Dennis; Taddei, Marco; Tetko, Igor; Tolnai, Domonkos; Vahdatifar, Sahar; Whitmer, Jonathan; Wieland, D. C. Florian; Willumeit-Roemer, Regine; Zuttel, Andreas; Smit, Berend

Single-molecule digital sizing of proteins in solution

NATURE COMMUNICATIONS

IF15.7

2024-09-04

OAAI

Krainer, Georg; Jacquat, Raphael P. B.; Schneider, Matthias M.; Welsh, Timothy J.; Fan, Jieyuan; Peter, Quentin A. E.; Andrzejewska, Ewa A.; Sneideriene, Greta; Czekalska, Magdalena A.; Ausserwoeger, Hannes; Chai, Lin; Arter, William E.; Saar, Kadi L.; Herling, Therese W.; Franzmann, Titus M.; Kosmoliaptsis, Vasilis; Alberti, Simon; Hartl, F. Ulrich; Lee, Steven F.; Knowles, Tuomas P. J.

Protein Condensate Atlas from predictive models of heteromolecular condensate composition 来自异分子冷凝物组成预测模型的蛋白质冷凝物图谱

NATURE COMMUNICATIONS

IF15.7

2024-07-10

OAAI

Saar, Kadi L.; Scrutton, Rob M.; Bloznelyte, Kotryna; Morgunov, Alexey S.; Good, Lydia L.; Lee, Alpha A.; Teichmann, Sarah A.; Knowles, Tuomas P. J.

α-Synuclein Oligomers Displace Monomeric α-Synuclein from Lipid Membranes Α-突触核蛋白寡聚体从脂质膜中置换单体 α-突触核蛋白

ACS NANO

IF16

2024-06-25

OAAI

Sneideriene, Greta; Czekalska, Magdalena A.; Xu, Catherine K.; Jayaram, Akhila K.; Krainer, Georg; Arter, William E.; Peter, Quentin A. E.; Castellana-Cruz, Marta; Saar, Kadi Liis; Levin, Aviad; Mueller, Thomas; Fiedler, Sebastian; Devenish, Sean R. A.; Fiegler, Heike; Kumita, Janet R.; Knowles, Tuomas P. J.

Microfluidics-based screening platform identifies a novel therapeutic approach to targeting EML4-ALK driven cancers

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Centore, Richard C.; Watson, Matthew; Doh, Julia; Cattin, Jerome; Sgambato, Cinzia; Alex, Amal; Sawant, Janhavi; Radhakrishnan, Prathima; Cornish, Jasmine; Howarth, Alex; Bharatham, Nagakumar; Arter, William E.; Qamar, Seema; Saar, Kadi L.; Williamson, Douglas; Seeber, Andrew; Groenewegen, Neils; Czekalska, Magdalena; Kartanas, Tadas; Ermann, Niklas; Taher, Ahmed; Knowles, Tuomas; Arora, Shilpi

Discovery of novel biomolecular condensate drug targets in oncology using in silico predictive tools

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Saar, Kadi L.; Rebmann, Marius; Kanchwala, Mohammed; Qamar, Seema; Radhakrishnan, Prathima; Cornish, Jasmine; Doh, Julia; Cattin, Jerome; Rotem, Assaf; Ghandi, Mahmoud; Seeber, Andrew; Centore, Richard C.; Teichmann, Sarah A.; Knowles, Tuomas; Arora, Shilpi

Pharmacological inhibition of the m6A RNA reader, YTHDC1, as a novel approach to targeting biomolecular condensates in cancer

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Centore, Richard C.; Charles, Mark; Arora, Mansi; Chen, Yiwen; Watson, Matthew; Kelley, Charlotte; Czekalska, Magdalena; Rebmann, Marius; Ghandi, Mahmoud; Cattin, Jerome; Bharatham, Nagakumar; Radhakrishnan, Prathima; Howarth, Alex; Rudlaff, Gale; Arter, William E.; Qamar, Seema; Saar, Kadi; Williamson, Douglas; Seeber, Andrew; Knowles, Tuomas; Arora, Shilpi

Targeting nucleic acid phase transitions as a mechanism of action for antimicrobial peptides

NATURE COMMUNICATIONS

IF15.7

2023-11-07

OAAI

Sneideris, Tomas; Erkamp, Nadia A.; Ausserwoger, Hannes; Saar, Kadi L.; Welsh, Timothy J.; Qian, Daoyuan; Katsuya-Gaviria, Kai; Johncock, Margaret L. L. Y.; Krainer, Georg; Borodavka, Alexander; Knowles, Tuomas P. J.

Turning high-throughput structural biology into predictive inhibitor design

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-03-06

OAAI

Saar, Kadi L.; McCorkindale, William; Fearon, Daren; Boby, Melissa; Barr, Haim; Ben-Shmuel, Amir; London, Nir; von Delft, Frank; Chodera, John D.; Lee, Alpha A.; COVID Moonshot, Alpha A.

Micromechanics of soft materials using microfluidics

MRS BULLETIN

IF4.9

2022-04-11

OAAI

Xu, Yufan; Zhu, Hongjia; Shen, Yi; Guttenplan, Alexander P. M.; Saar, Kadi L.; Lu, Yuqian; Vigolo, Daniele; Itzhaki, Laura S.; Knowles, Tuomas P. J.

Surface Electrostatics Govern the Emulsion Stability of Biomolecular Condensates

NANO LETTERS

IF9.1

2022-01-10

OAAI

Welsh, Timothy J.; Krainer, Georg; Espinosa, Jorge R.; Joseph, Jerelle A.; Sridhar, Akshay; Jahnel, Marcus; Arter, William E.; Saar, Kadi L.; Alberti, Simon; Collepardo-Guevara, Rosana; Knowles, Tuomas P. J.

Liquid-liquid phase separation underpins the formation of replication factories in rotaviruses

EMBO JOURNAL

IF8.3

2021-09-15

OAAI

Geiger, Florian; Acker, Julia; Papa, Guido; Wang, Xinyu; Arter, William E.; Saar, Kadi L.; Erkamp, Nadia A.; Qi, Runzhang; Bravo, Jack Pk; Strauss, Sebastian; Krainer, Georg; Burrone, Oscar R.; Jungmann, Ralf; Knowles, Tuomas P. J.; Engelke, Hanna; Borodavka, Alexander

Deformable and Robust Core-Shell Protein Microcapsules Templated by Liquid-Liquid Phase-Separated Microdroplets

ADVANCED MATERIALS INTERFACES

IF4.4

2021-09-13

OAAI

Xu, Yufan; Shen, Yi; Michaels, Thomas C. T.; Baumann, Kevin N.; Vigolo, Daniele; Peter, Quentin; Lu, Yuqian; Saar, Kadi L.; Vella, Dominic; Zhu, Hongjia; Li, Bing; Yang, He; Guttenplan, Alexander P. M.; Rodriguez-Garcia, Marc; Klenerman, David; Knowles, Tuomas P. J.

Learning the molecular grammar of protein condensates from sequence determinants and embeddings

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-04-07

100

OAAI

Saar, Kadi L.; Morgunov, Alexey S.; Qi, Runzhang; Arter, William E.; Krainer, Georg; Lee, Alpha A.; Knowles, Tuomas P. J.

Machine learning-aided protein identification from multidimensional signatures 来自多维特征的机器学习辅助蛋白质识别

LAB ON A CHIP

IF5.4

2021-01-01

OAAI

Zhang, Yuewen; Wright, Maya A.; Saar, Kadi L.; Challa, Pavankumar; Morgunov, Alexey S.; Peter, Quentin A. E.; Devenish, Sean; Dobson, Christopher M.; Knowles, Tuomas P. J.

Rapid Structural, Kinetic, and Immunochemical Analysis of Alpha-Synuclein Oligomers in Solution 溶液中 α-突触核蛋白低聚物的快速结构，动力学和免疫化学分析

NANO LETTERS

IF9.1

2020-10-20

OAAI

Arter, William E.; Xu, Catherine K.; Castellana-Cruz, Marta; Herling, Therese W.; Krainer, Georg; Saar, Kadi L.; Kumita, Janet R.; Dobson, Christopher M.; Knowles, Tuomas P. J.

Multidimensional protein characterisation using microfluidic post-column analysis

LAB ON A CHIP

IF5.4

2020-01-01

OAAI

Scheidt, Tom; Kartanas, Tadas; Peter, Quentin; Schneider, Matthias M.; Saar, Kadi L.; Mueller, Thomas; Challa, Pavan Kumar; Levin, Aviad; Devenish, Sean; Knowles, Tuomas P. J.

Rapid two-dimensional characterisation of proteins in solution

MICROSYSTEMS & NANOENGINEERING

IF9.9

2019-07-01

OAAI

Saar, Kadi L.; Peter, Quentin; Mueller, Thomas; Challa, Pavan K.; Herling, Therese W.; Knowles, Tuomas P. J.

Quaternization of Vinyl/Alkynyl Pyridine Enables Ultrafast Cysteine-Selective Protein Modification and Charge Modulation 乙烯基/炔基吡啶的季铵化实现了超快的半胱氨酸选择性蛋白质修饰和电荷调节

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2019-04-09

OAAI

Matos, Maria J.; Navo, Claudio D.; Hakala, Tuuli; Ferhati, Xhenti; Guerreiro, Ana; Hartmann, David; Bernardim, Barbara; Saar, Kadi L.; Companon, Ismael; Corzana, Francisco; Knowles, Tuomas P. J.; Jimenez-Oses, Gonzalo; Bernardes, Goncalo J. L.

研究方向