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A

Andreas Ostermann

Technical University Munich

H指数:30

被引数:2,692

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Structural basis of hydride and proton transfer reactions revealed by the detection of hydrogen atoms in mammalian NADH-cytochrome b5 reductase

哺乳动物NADH-细胞色素b5还原酶中氢原子检测揭示的氢化物和质子转移反应的结构基础

IF4.3

2025-10-300

PRE

Neutron crystallography and quantum chemical analysis of bilin reductase PcyA mutants reveal substrate and catalytic residue protonation states

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2023-01-012

OAAI

How a Fragment Draws Attention to Selectivity Discriminating Features between the Related Proteases Trypsin and Thrombin

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2021-01-202

PREAI

Visualizing the protons in a metalloenzyme electron proton transfer pathway

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-03-0922

OA

A molecular mechanism for transthyretin amyloidogenesis

转甲状腺素蛋白淀粉样蛋白生成的分子机制

NATURE COMMUNICATIONS

IF15.7

2019-02-25105

OAAI

Using neutron crystallography to elucidate the basis of selective inhibition of carbonic anhydrase by saccharin and a derivative

JOURNAL OF STRUCTURAL BIOLOGY

IF5.1

2019-02-0113

OAAI

Structural and thermodynamic characterization of the binding of isoliquiritigenin to the first bromodomain of BRD4

异甘草素与BRD4的第一个溴结构域结合的结构和热力学表征

IF4.2

2019-01-108

OAAI

Intriguing role of water in protein-ligand binding studied by neutron crystallography on trypsin complexes

通过中子晶体学对胰蛋白酶复合物研究的蛋白质-配体结合中水的有趣作用

NATURE COMMUNICATIONS

IF15.7

2018-09-03152

OAAI

Crystal Growth of a Bilin Reductase PcyA I86D Mutant-Substrate Complex for Neutron Crystallography

CRYSTAL GROWTH & DESIGN

IF3.4

2018-07-113

PREAI

Elucidation of Hydrogen Bonding Patterns in Ligand-Free, Lactose- and Glycerol-Bound Galectin-3C by Neutron Crystallography to Guide Drug Design

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2018-04-1933

OAAI

Charges Shift Protonation: Neutron Diffraction Reveals that Aniline and 2-Aminopyridine Become Protonated Upon Binding to Trypsin

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2017-03-2819

PREAI

Direct visualization of a Fe(IV)-OH intermediate in a heme enzyme

NATURE COMMUNICATIONS

IF15.7

2016-11-2965

OAAI

Neutron structures of the Helicobacter pylori 5′-methylthioadenosine nucleosidase highlight proton sharing and protonation states

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2016-11-1629

OAAI

Exploring the Mechanism of β-Lactam Ring Protonation in the Class A β-lactamase Acylation Mechanism Using Neutron and X-ray Crystallography

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2015-12-0251

OAAI

Direct determination of protonation states and visualization of hydrogen bonding in a glycoside hydrolase with neutron crystallography

用中子晶体学直接测定糖苷水解酶中的质子化状态和氢键的可视化

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2015-09-2142

OAAI

Protonation State and Hydration of Bisphosphonate Bound to Farnesyl Pyrophosphate Synthase

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2015-09-0426

PREAI

Joint neutron crystallographic and NMR solution studies of Tyr residue ionization and hydrogen bonding: Implications for enzyme-mediated proton transfer

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2015-04-2042

OAAI

Neutron and X-ray Crystal Structures of a Perdeuterated Enzyme Inhibitor Complex Reveal the Catalytic Proton Network of the Toho-1 β-Lactamase for the Acylation Reaction

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2013-02-0147

OAAI

Nature of the Bonding in Metal-Silane σ-Complexes

INORGANIC CHEMISTRY

IF4.7

2009-01-1563

OA

Hydrogen atoms in proteins: Positions and dynamics

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2003-08-2258

OAAI