未登录 分享 收藏
分享 收藏
Environmental Contributions to Proton Sharing in Protein Low-Barrier Hydrogen Bonds 环境对蛋白质低势垒氢键中质子共享的贡献 Lin, Jiusheng; Gerlits, Oksana; Kneller, Daniel W.; Weiss, Kevin L.; Coates, Leighton; Clarke, Jennifer L.; Hix, Mark A.; Effah, Solomon Y.; Kovalevsky, Andrey; Walker, Alice R.; Wilson, Mark A. 分享 收藏
分享 收藏
分享 收藏
Effects of SARS-CoV-2 Main Protease Mutations at Positions L50, E166, and L167 Rendering Resistance to Covalent and Noncovalent Inhibitors Kovalevsky, Andrey; Aniana, Annie; Ghirlando, Rodolfo; Coates, Leighton; Drago, Victoria N.; Wear, Lauren; Gerlits, Oksana; Nashed, Nashaat T.; Louis, John M. 分享 收藏
Dual Enhancement of Thermostability and Activity of Xylanase through Computer-Aided Rational Design 通过计算机辅助合理设计双重增强木聚糖酶的热稳定性和活性 Lu, Meizi; Li, Zhihong; Zhuang, Hui; Yang, Shuanghao; Zhao, Xingchu; Feng, Ruirui; Shen, Haoyu; Kovalevsky, Andrey; Zhang, Shengkai; Xie, Zaipeng; Li, Xin; Shen, Qirong; Wan, Qun 分享 收藏
分享 收藏
分享 收藏
分享 收藏
分享 收藏
分享 收藏
分享 收藏
分享 收藏
分享 收藏
AI-Accelerated Design of Targeted Covalent Inhibitors for SARS-CoV-2 Joshi, Rajendra P.; Schultz, Katherine J.; Wilson, Jesse William; Kruel, Agustin; Varikoti, Rohith Anand; Kombala, Chathuri J.; Kneller, Daniel W.; Galanie, Stephanie; Phillips, Gwyndalyn; Zhang, Qiu; Coates, Leighton; Parvathareddy, Jyothi; Surendranathan, Surekha; Kong, Ying; Clyde, Austin; Ramanathan, Arvind; Jonsson, Colleen B.; Brandvold, Kristoffer R.; Zhou, Mowei; Head, Martha S.; Kovalevsky, Andrey; Kumar, Neeraj 分享 收藏
分享 收藏
Structural and functional characterization of NEMO cleavage by SARS-CoV-2 3CLpro Hameedi, Mikhail Ali; Prates, Erica T.; Garvin, Michael R.; Mathews, Irimpan; Amos, B. Kirtley; Demerdash, Omar; Bechthold, Mark; Iyer, Mamta; Rahighi, Simin; Kneller, Daniel W.; Kovalevsky, Andrey; Irle, Stephan; Van-Quan Vuong; Mitchell, Julie C.; Labbe, Audrey; Galanie, Stephanie; Wakatsuki, Soichi; Jacobson, Daniel 分享 收藏
The mechanisms of catalysis and ligand binding for the SARS-CoV-2 NSP3 macrodomain from neutron and x-ray diffraction at room temperature Correy, Galen J.; Kneller, Daniel W.; Phillips, Gwyndalyn; Pant, Swati; Russi, Silvia; Cohen, Aina E.; Meigs, George; Holton, James M.; Gahbauer, Stefan; Thompson, Michael C.; Ashworth, Alan; Coates, Leighton; Kovalevsky, Andrey; Meilleur, Flora; Fraser, James S. 分享 收藏
分享 收藏