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Lipid nanoparticles and transcranial focused ultrasound enhance the delivery of SOD1 antisense oligonucleotides to the murine brain for ALS therapy 脂质纳米颗粒和经颅聚焦超声增强SOD1反义寡核苷酸在ALS治疗中对小鼠脑部的递送 Ediriweera, Gayathri R.; Sivaram, Amal J.; Cowin, Gary; Brown, Mikayla L.; Mcalary, Luke; Lum, Jeremy S.; Fletcher, Nicholas L.; Robinson, Liam; Simpson, Joshua D.; Chen, Liyu; Wasielewska, Joanna M.; Byrne, Ella; Finnie, John W.; Manavis, Jim; White, Anthony R.; Yerbury, Justin J.; Thurecht, Kristofer J.; Vine, Kara L. 分享 收藏
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Drug repurposing candidates for amyotrophic lateral sclerosis using common and rare genetic variants 利用常见和稀有遗传变异筛选肌萎缩侧索硬化症药物重定位候选药物 Gerring, Zachary F.; Bhalala, Oneil G.; Fearnley, Liam G.; Oikari, Lotta E.; White, Anthony R.; Derks, Eske M.; Watson, Rosie; Yassi, Nawaf; Bahlo, Melanie; Reay, William R. 分享 收藏
Integrated elemental analysis supports targeting copper perturbations as a therapeutic strategy in multiple sclerosis Hilton, James B. W.; Kysenius, Kai; Liddell, Jeffrey R.; Mercer, Stephen W.; Rautengarten, Carsten; Hare, Dominic J.; Buncic, Gojko; Paul, Bence; Murray, Simon S.; McLean, Catriona A.; Kilpatrick, Trevor J.; Beckman, Joseph S.; Ayton, Scott; Bush, Ashley I.; White, Anthony R.; Roberts, Blaine R.; Donnelly, Paul S.; Crouch, Peter J. 分享 收藏
A patient-derived amyotrophic lateral sclerosis blood-brain barrier model for focused ultrasound-mediated anti-TDP-43 antibody delivery 用于聚焦超声介导的anti-TDP-43抗体递送的患者衍生的肌萎缩侧索硬化血脑屏障模型 Wasielewska, Joanna M.; Chaves, Juliana C. S.; Cabral-da-Silva, Mauricio Castro; Pecoraro, Martina; Viljoen, Stephani J.; Nguyen, Tam Hong; La Bella, Vincenzo; Oikari, Lotta E.; Ooi, Lezanne; White, Anthony R. 分享 收藏
Differential Cytokine Responses of APOE3 and APOE4 Blood-brain Barrier Cell Types to SARS-CoV-2 Spike Proteins APOE3和APOE4血脑屏障细胞类型对SARS-CoV-2刺突蛋白的不同细胞因子反应 Chaves, Juliana C. S.; Milton, Laura A.; Stewart, Romal; Senapati, Tarosi; Rantanen, Laura M.; Wasielewska, Joanna M.; Lee, Serine; Hernandez, Damian; Mcinnes, Lachlan; Quek, Hazel; Pebay, Alice; Donnelly, Paul S.; White, Anthony R.; Oikari, Lotta E. 分享 收藏
Advanced patient-specific microglia cell models for pre-clinical studies in Alzheimer's disease (vol 21, 1, 2024) Cuni-Lopez, Carla; Stewart, Romal; Oikari, Lotta E.; Nguyen, Tam Hong; Roberts, Tara L.; Sun, Yifan; Guo, Christine C.; Lupton, Michelle K.; White, Anthony R.; Quek, Hazel 分享 收藏
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Patient-Derived Blood-Brain Barrier Model for Screening Copper Bis(thiosemicarbazone) Complexes as Potential Therapeutics in Alzheimer's Disease 用于筛选铜双 (缩氨基硫脲) 配合物作为阿尔茨海默氏病潜在治疗药物的患者来源的血脑屏障模型 Wasielewska, Joanna M.; Szostak, Kathryn; Mcinnes, Lachlan E.; Quek, Hazel; Chaves, Juliana C. S.; Liddell, Jeffrey R.; Koistinaho, Jari; Oikari, Lotta E.; Donnelly, Paul S.; White, Anthony R. 分享 收藏
Evidence for disrupted copper availability in human spinal cord supports CuII(atsm) as a treatment option for sporadic cases of ALS Hilton, James B. W.; Kysenius, Kai; Liddell, Jeffrey R.; Mercer, Stephen W.; Paul, Bence; Beckman, Joseph S.; Mclean, Catriona A.; White, Anthony R.; Donnelly, Paul S.; Bush, Ashley I.; Hare, Dominic J.; Roberts, Blaine R.; Crouch, Peter J. 分享 收藏
Advanced patient-specific microglia cell models for pre-clinical studies in Alzheimer's disease Cuni-Lopez, Carla; Stewart, Romal; Oikari, Lotta E.; Nguyen, Tam Hong; Roberts, Tara L.; Sun, Yifan; Guo, Christine C.; Lupton, Michelle K.; White, Anthony R.; Quek, Hazel 分享 收藏
Microglial ferroptotic stress causes non-cell autonomous neuronal death Liddell, Jeffrey R.; Hilton, James B. W.; Kysenius, Kai; Billings, Jessica L.; Nikseresht, Sara; Mcinnes, Lachlan E.; Hare, Dominic J.; Paul, Bence; Mercer, Stephen W.; Belaidi, Abdel A.; Ayton, Scott; Roberts, Blaine R.; Beckman, Joseph S.; Mclean, Catriona A.; White, Anthony R.; Donnelly, Paul S.; Bush, Ashley I.; Crouch, Peter J. 分享 收藏
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An Alzheimer's Disease Patient-Derived Olfactory Stem Cell Model Identifies Gene Expression Changes Associated with Cognition Rantanen, Laura M.; Bitar, Maina; Lampinen, Riikka; Stewart, Romal; Quek, Hazel; Oikari, Lotta E.; Cuni-Lopez, Carla; Sutharsan, Ratneswary; Thillaiyampalam, Gayathri; Iqbal, Jamila; Russell, Daniel; Penttila, Elina; Lopponen, Heikki; Lehtola, Juha-Matti; Saari, Toni; Hannonen, Sanna; Koivisto, Anne M.; Haupt, Larisa M.; Mackay-Sim, Alan; Cristino, Alexandre S.; Kanninen, Katja M.; White, Anthony R. 分享 收藏
Neuron-astrocyte transmitophagy is altered in Alzheimer's disease 阿尔茨海默氏病中神经元-星形胶质细胞的吞噬改变 Lampinen, Riikka; Belaya, Irina; Saveleva, Liudmila; Liddell, Jeffrey R.; Rait, Dzhessi; Huuskonen, Mikko T.; Giniatullina, Raisa; Sorvari, Annika; Soppela, Liisi; Mikhailov, Nikita; Boccuni, Isabella; Giniatullin, Rashid; Cruz-Haces, Marcela; Konovalova, Julia; Koskuvi, Marja; Domanskyi, Andrii; Hamalainen, Riikka H.; Goldsteins, Gundars; Koistinaho, Jari; Malm, Tarja; Chew, Sweelin; Rilla, Kirsi; White, Anthony R.; Marsh-Armstrong, Nicholas; Kanninen, Katja M. 分享 收藏
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