Sheo B. Singh - Publications, H-index & Citations

Sheo B. Singh

drew university

58H指数

342论文数

1.4W被引数

收录论文 109

发表时间

Insight and scope of cis-selectivity of Wittig reaction for the synthesis of mono and multi-substituted stilbenes Wittig反应在单取代和多取代 stilbenes 合成中的顺式选择性的见解与范围

RESULTS IN CHEMISTRY

IF4.2

2025-12-01

OAAI

Demar, Linel L.; Singh, Sheo B.

History and Prospects of Drug Discovery and Development Collaboration between Industry and Academia

JOURNAL OF NATURAL PRODUCTS

IF3.6

2024-03-30

PREAI

Singh, Sheo B.; Martin, Gary E.; Mckittrick, Brian; Crowther, Jonathan; Fraenkel, Howard; Lunn, Charles; Bayne, Marvin; Perkins, John B.; Gullo, Vincent

Discovery, synthesis, activities, structure-activity relationships, and clinical development of combretastatins and analogs as anticancer drugs. A comprehensive review

NATURAL PRODUCT REPORTS

IF10.6

2024-01-01

PREAI

Singh, Sheo B.

Nocathiacin, Thiazomycin, and Polar Analogs Are Highly Effective Agents against Toxigenic Clostridioides difficile

JOURNAL OF NATURAL PRODUCTS

IF3.6

2022-04-05

PREAI

Singh, Sheo B.; Miesel, Lynn; Kramer, Susanne; Xu, Libo; Li, Fangbio; Lan, Jing; Lipari, Phillip; Polishook, Jon D.; Liu, Gongjie; Liang, Lianzhu; Flattery, Amy M.

Discovery and Development of Dolastatin 10-Derived Antibody Drug Conjugate Anticancer Drugs

JOURNAL OF NATURAL PRODUCTS

IF3.6

2022-01-24

PREAI

Singh, Sheo B.

Rapid, Selective, and Sensitive Method for Semitargeted Discovery of Congeneric Natural Products by Liquid Chromatography Tandem Mass Spectrometry

JOURNAL OF NATURAL PRODUCTS

IF3.6

2021-02-01

PREAI

Herath, Kithsiri B.; Previs, Stephen F.; Roddy, Thomas P.; Attygalle, Athula B.; Gonzalez, Ignacio; Genilloud, Olga; Singh, Sheo B.

What is an ideal antibiotic? Discovery challenges and path forward

BIOCHEMICAL PHARMACOLOGY

IF5.6

2017-06-01

170

PREAI

Singh, Sheo B.; Young, Katherine; Silver, Lynn L.

Discovery and development of kibdelomycin, a new class of broad-spectrum antibiotics targeting the clinically proven bacterial type II topoisomerase

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2016-12-01

PREAI

Singh, Sheo B.

In Vitro and In Vivo Characterization of the Novel Oxabicyclooctane-Linked Bacterial Topoisomerase Inhibitor AM-8722, a Selective, Potent Inhibitor of Bacterial DNA Gyrase

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2016-08-01

OAAI

Tan, Christopher M.; Gill, Charles J.; Wu, Jin; Toussaint, Nathalie; Yin, Jingjun; Tsuchiya, Takayuki; Garlisi, Charles G.; Kaelin, David; Meinke, Peter T.; Miesel, Lynn; Olsen, David B.; Lagrutta, Armando; Fukuda, Hideyuki; Kishii, Ryuta; Takei, Masaya; Oohata, Kouhei; Takeuchi, Tomoko; Shibue, Taku; Takano, Hisashi; Nishimura, Akinori; Fukuda, Yasumichi; Singh, Sheo B.

Kibdelomycin Is a Bactericidal Broad-Spectrum Aerobic Antibacterial Agent

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2015-06-01

OAAI

Singh, Sheo B.; Dayananth, Priya; Balibar, Carl J.; Garlisi, Charles G.; Lu, Jun; Kishii, Ryuta; Takei, Masaya; Fukuda, Yasumichi; Ha, Sookhee; Young, Katherine

Design, Synthesis, Structure-Function Relationship, Bioconversion, and Pharmacokinetic Evaluation of Ertapenem Prodrugs

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2014-10-14

PREAI

Singh, Sheo B.; Rindgen, Diane; Bradley, Prudence; Suzuki, Takao; Wang, Nengxue; Wu, Hao; Zhang, Basheng; Wang, Li; Ji, Chongmin; Yu, Hongshi; Soll, Richard M.; Olsen, David B.; Meinke, Peter T.; Nicoll-Griffith, Deborah A.

Structures of Kibdelomycin Bound to Staphylococcus aureus GyrB and ParE Showed a Novel U-Shaped Binding Mode

ACS CHEMICAL BIOLOGY

IF3.8

2014-07-03

106

PREAI

Lu, Jun; Patel, Sangita; Sharma, Nandini; Soisson, Stephen M.; Kishii, Ryuta; Takei, Masaya; Fulkuda, Yasumichi; Lumb, Kevin J.; Singh, Sheo B.

Circumambulatory Movement of Negative Charge (Ring Walk) during Gas-Phase Dissociation of 2,3,4-Trimethoxybenzoate Anion

JOURNAL OF ORGANIC CHEMISTRY

IF3.6

2014-04-28

PREAI

Herath, Kithsiri B.; Weisbecker, Carl S.; Singh, Sheo B.; Attygalle, Athula B.

Kibdelomycin Is a Potent and Selective Agent against Toxigenic Clostridium difficile

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2014-04-01

OAAI

Miesel, Lynn; Hecht, David W.; Osmolski, James R.; Gerding, Dale; Flattery, Amy; Li, Fangbiao; Lan, Jing; Lipari, Philip; Polishook, Jon D.; Liang, Lianzhu; Liu, Jenny; Olsen, David B.; Singh, Sheo B.

Oxabicyclooctane-Linked Novel Bacterial Topoisomerase Inhibitors as Broad Spectrum Antibacterial Agents

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2014-03-14

OAAI

Singh, Sheo B.; Kaelin, David E.; Wu, Jin; Miesel, Lynn; Tan, Christopher M.; Meinke, Peter T.; Olsen, David; Lagrutta, Armando; Bradley, Prudence; Lu, Jun; Patel, Sangita; Rickert, Keith W.; Smith, Robert F.; Soisson, Stephen; Wei, Changqing; Fukuda, Hideyuki; Kishii, Ryuta; Takei, Masaya; Fukuda, Yasumichi

Isolation, Structure Elucidation, and Biological Activity of Altersolanol P Using Staphylococcus aureus Fitness Test Based Genome-Wide Screening

JOURNAL OF NATURAL PRODUCTS

IF3.6

2014-01-15

PREAI

Ondeyka, John; Buevich, Alexei V.; Williamson, R. Thomas; Zink, Deborah L.; Polishook, Jon D.; Occi, James; Vicente, Francisca; Basilio, Angela; Bills, Gerald F.; Donald, Robert G. K.; Phillips, John W.; Goetz, Michael A.; Singh, Sheo B.

Screening strategies for discovery of antibacterial natural products

EXPERT REVIEW OF ANTI-INFECTIVE THERAPY

IF3.8

2014-01-10

PREAI

Singh, Sheo B.; Young, Katherine; Miesel, Lynn

Discovery and development of first in class antifungal caspofungin (CANCIDAS®)-A case study

NATURAL PRODUCT REPORTS

IF10.6

2014-01-01

124

PREAI

Balkovec, James M.; Hughes, David L.; Masurekar, Prakash S.; Sable, Carole A.; Schwartz, Robert E.; Singh, Sheo B.

Structure of the Bacterial Deacetylase LpxC Bound to the Nucleotide Reaction Product Reveals Mechanisms of Oxyanion Stabilization and Proton Transfer

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2013-11-01

OAAI

Clayton, Gina M.; Klein, Daniel J.; Rickert, Keith W.; Patel, Sangita B.; Kornienko, Maria; Zugay-Murphy, Joan; Reid, John C.; Tummala, Srivanya; Sharma, Sujata; Singh, Sheo B.; Miesel, Lynn; Lumb, Kevin J.; Soisson, Stephen M.

Design, Synthesis, and Evaluation of Prodrugs of Ertapenem 厄他培南前药的设计、合成与评价

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2013-07-09

OAAI

Singh, Sheo B.; Rindgen, Diane; Bradley, Prudence; Cama, Lovji; Sun, Wanying; Hafey, Michael J.; Suzuki, Takao; Wang, Nengxue; Wu, Hao; Zhang, Basheng; Wang, Li; Ji, Chongmin; Yu, Hongshi; Soll, Richard; Olsen, David B.; Meinke, Peter T.; Nicoll-Griffith, Deborah A.

研究方向