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M

Matthew Leventhal

broad institute
H指数:12
被引数:1,863

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荣誉奖项

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Intersecting impact of CAG repeat and huntingtin knockout in stem cell-derived cortical neurons

CAG重复与亨廷顿基因敲除在干细胞来源皮层神经元中的交叉影响

NEUROBIOLOGY OF DISEASE
IF5.6
2025-06-010
OAAI
Stocksdale, Jennifer T.; Leventhal, Matthew J.; Lam, Stephanie; Xu, Yu-Xin; Wang, Yang Oliver; Wang, Keona Q.; Thomas, Reuben; Faghihmonzavi, Zohreh; Raghav, Yogindra; Smith, Charlene; Wu, Jie; Miramontes, Ricardo; Sarda, Kanchan; Johnston, Heather; Shin, Min-Gyoung; Huang, Terry; Foster, Mikelle; Barch, Mariya; Amirani, Naufa; Paiz, Chris; Easter, Lindsay; Duderstadt, Erse; Vaibhav, Vineet; Sundararaman, Niveda; Felsenfeld, Dan P.; Vogt, Thomas F.; Van Eyk, Jennifer; Finkbeiner, Steve; Kaye, Julia A.; Thompson, Leslie M.
An integrative systems-biology approach defines mechanisms of Alzheimer's disease neurodegeneration

整合系统生物学方法定义了阿尔茨海默病神经退行性变的机制

NATURE COMMUNICATIONS
IF15.7
2025-05-200
OA
Leventhal, Matthew J.; Zanella, Camila A.; Kang, Byunguk; Peng, Jiajie; Gritsch, David; Liao, Zhixiang; Bukhari, Hassan; Wang, Tao; Pao, Ping-Chieh; Danquah, Serwah; Benetatos, Joseph; Nehme, Ralda; Farhi, Samouil; Tsai, Li-Huei; Dong, Xianjun; Scherzer, Clemens R.; Feany, Mel B.
Calreticulin mutant myeloproliferative neoplasms induce MHC-I skewing, which can be overcome by an optimized peptide cancer vaccine

钙网蛋白突变体骨髓增生性肿瘤诱导mhc-i偏斜，这可以通过优化的肽癌症疫苗来克服

SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2022-06-1512
PRE
Gigoux, Mathieu; Holmstrom, Morten O.; Zappasodi, Roberta; Park, Joseph J.; Pourpe, Stephane; Bozkus, Cansu Cimen; Mangarin, Levi M. B.; Redmond, David; Verma, Svena; Schad, Sara; George, Mariam M.; Venkatesh, Divya; Ghosh, Arnab; Hoyos, David; Molvi, Zaki; Kamaz, Baransel; Marneth, Anna E.; Duke, William; Leventhal, Matthew J.; Jan, Max; Ho, Vincent T.; Hobbs, Gabriela S.; Knudsen, Trine Alma; Skov, Vibe; Kjaer, Lasse; Larsen, Thomas Stauffer; Hansen, Dennis Lund; Lindsley, R. Coleman; Hasselbalch, Hans; Grauslund, Jacob H.; Lisle, Thomas L.; Met, Ozcan; Wilkinson, Patrick; Greenbaum, Benjamin; Sepulveda, Manuel A.; Chan, Timothy; Rampal, Raajit; Andersen, Mads H.; Abdel-Wahab, Omar; Bhardwaj, Nina; Wolchok, Jedd D.; Mullally, Ann; Merghoub, Taha
ZBTB33 Is Mutated in Clonal Hematopoiesis and Myelodysplastic Syndromes and Impacts RNA Splicing
BLOOD CANCER DISCOVERY
IF11.5
2021-07-1423
OA
Beauchamp, Ellen M.; Leventhal, Matthew; Bernard, Elsa; Hoppe, Emma R.; Todisco, Gabriele; Creignou, Maria; Galli, Anna; Castellano, Cecilia A.; McConkey, Marie; Tarun, Akansha; Wong, Waihay; Schenone, Monica; Stanclift, Caroline; Tanenbaum, Benjamin; Malolepsza, Edyta; Nilsson, Bjorn; Bick, Alexander G.; Weinstock, Joshua S.; Miller, Mendy; Niroula, Abhishek; Dunford, Andrew; Taylor-Weiner, Amaro; Wood, Timothy; Barbera, Alex; Anand, Shankara; Psaty, Bruce M.; Desai, Pinkal; Cho, Michael H.; Johnson, Andrew D.; Loos, Ruth; MacArthur, Daniel G.; Lek, Monkol; Neuberg, Donna S.; Lage, Kasper; Carr, Steven A.; Hellstrom-Lindberg, Eva; Malcovati, Luca; Papaemmanuil, Elli; Stewart, Chip; Getz, Gad; Bradley, Robert K.; Jaiswal, Siddhartha; Ebert, Benjamin L.
MHC-I SKEWING IN MUTANT CALRETICULIN-POSITIVE MYELOPROLIFERATIVE NEOPLASMS IS COUNTERED BY HETEROCLITIC PEPTIDE CANCER VACCINATION
JOURNAL FOR IMMUNOTHERAPY OF CANCER
IF10.6
2020-11-090
OAAI
Gigoux, Mathieu; Zappasodi, Roberta; Park, Joseph; Pourpe, Stephane; Ghosh, Arnab; Bozkus, Cansu Cimen; Mangarin, Levi; Redmond, David; Verma, Svena; Schad, Sara; Duke, William; Jan, Max; Leventhal, Matthew; Ho, Vincent; Hobbs, Gabriela; Knudsen, Trine Alma; Skov, Vibe; Kjaer, Lasse; Larsen, Thomas Stauffer; Hansen, Dennis Lund; Lindsley, R. Coleman; Hasselbalch, Hans; Grauslund, Jacob; Andersen, Mads; Holmstrom, Morten; Chan, Timothy; Rampal, Raajit; Abdel-Wahab, Omar; Bhardwaj, Nina; Wolchok, Jedd; Mullally, Ann; Merghoub, Taha
Clonal hematopoiesis is associated with adverse outcomes in multiple myeloma patients undergoing transplant
NATURE COMMUNICATIONS
IF15.7
2020-06-12125
OAAI
Mouhieddine, Tarek H.; Sperling, Adam S.; Redd, Robert; Park, Jihye; Leventhal, Matthew; Gibson, Christopher J.; Manier, Salomon; Nassar, Amin H.; Capelletti, Marzia; Huynh, Daisy; Bustoros, Mark; Sklavenitis-Pistofidis, Romanos; Tahri, Sabrin; Hornburg, Kalvis; Dumke, Henry; Itani, Muhieddine M.; Boehner, Cody J.; Liu, Chia-Jen; AlDubayan, Saud H.; Reardon, Brendan; Van Allen, Eliezer M.; Keats, Jonathan J.; Stewart, Chip; Mehr, Shaadi; Auclair, Daniel; Schlossman, Robert L.; Munshi, Nikhil C.; Anderson, Kenneth C.; Steensma, David P.; Laubach, Jacob P.; Richardson, Paul G.; Ritz, Jerome; Ebert, Benjamin L.; Soiffer, Robert J.; Trippa, Lorenzo; Getz, Gad; Neuberg, Donna S.; Ghobrial, Irene M.
Recurrent genetic HLA loss in AML relapsed after matched unrelated allogeneic hematopoietic cell transplantation
BLOOD ADVANCES
IF7.1
2019-07-1956
OA
Jan, Max; Leventhal, Matthew J.; Morgan, Elizabeth A.; Wengrod, Jordan C.; Nag, Anwesha; Drinan, Samantha D.; Wollison, Bruce M.; Ducar, Matthew D.; Thorner, Aaron R.; Leppanen, Scott; Baronas, Jane; Stevens, Jonathan; Lane, William J.; Kekre, Natasha; Ho, Vincent T.; Koreth, John; Cutler, Corey S.; Nikiforow, Sarah; Alyea, Edwin P., III; Antin, Joseph H.; Soiffer, Robert J.; Ritz, Jerome; Lindsley, R. Coleman; Ebert, Benjamin L.
A dominant-negative effect drives selection of TP53 missense mutations in myeloid malignancies

显性-负效应驱动选择 <i>TP53</i> 髓系恶性肿瘤的错义突变

Science
IF45.8
2019-01-010
OAAI
Steffen Boettcher; Peter Grant Miller; Rohan Sharma; Marie Ellen McConkey; Matthew Joseph Leventhal; Andrei V. Krivtsov; Andrew O. Giacomelli; Waihay J. Wong; Jesi Kim; Sherry X. Chao; Kari J. Kurppa; Xiaoping Yang; Kirsten Milenkowic; Federica Piccioni; David E. Root; Frank G. Rücker; Yael Flamand; Donna S Neuberg; Robert Coleman Lindsley; Pasi Antero Janne; William C. Hahn; Tyler Jacks; Hartmut Döhner; Scott A. Armstrong; Benjamin L. Ebert

研究方向

暂未获取到该数据
B
Benjamin L. Ebert
H 指数:122论文数:775被引数:15.5万
M
Max Jan
H 指数:22论文数:112被引数:5,464
D
Donna Neuberg
H 指数:155论文数:1,709被引数:10.2万
R
R. Coleman Lindsley
H 指数:43论文数:233被引数:1.5万
V
Vincent T. Ho
H 指数:86论文数:601被引数:2.6万
X
Xianjun Dong
H 指数:32论文数:91被引数:8,714
H
Hassan Bukhari
H 指数:8论文数:16被引数:259
M
Mads Hald Andersen
H 指数:50论文数:410被引数:1.0万
G
Gad Getz
H 指数:248论文数:1,851被引数:35.3万
J
Jerome Ritz
H 指数:128论文数:1,200被引数:6.0万