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M

Max Jan

massachusetts general hospital
H指数:22
被引数:5,464

个人简介

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教育背景

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工作经历

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荣誉奖项

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Genomic correlates of clinical CAR T cell activity

临床CAR T细胞活性的基因组相关性

Science Immunology
IF16.3
2026-07-240
PRE
Mark B. Leick; Baihe Sun; Filippo Birocchi; Kathleen M. E. Gallagher; Alexandra Bratt; Seunghun Han; Grace Martin; Harrison J. Silva; Rebecca C. Larson; Tyler M. Chinsky; Hoyin Chu; Christopher R. Reilly; Michael C. Kann; Bryan D. Choi; Sabrina Camp; Riaz Gillani; Merle Phillips; Tamina Kienka; Stefanie R. Bailey; Charlotte E. Graham; Max Jan; Nicholas S. Moore; Nora Horick; Justin Budka; Simone Filosto; Chad M. Williams; Ali Hosseini Rad; Rhine R. Shen; Eliezer Van Allen; Saud AlDubayan; Marcela V. Maus
Genetic retargeting of E3 ligases to enhance CAR T cell therapy
CELL CHEMICAL BIOLOGY
IF7.2
2024-02-017
PRE
Lane, Isabel C.; Kembuan, Gabriele; Carreiro, Jeannie; Kann, Michael C.; Lin, William; Bouffard, Amanda A.; Kreuzer, Johannes; Morris, Robert; Schneider, Emily M.; Kim, Joanna Y.; Zou, Charles; Salas-Benito, Diego; Gasser, Jessica A.; Leick, Mark B.; Slabicki, Mikolaj; Haas, Wilhelm; V. Maus, Marcela; Jan, Max
Chemical genetic control of cytokine signaling in CAR-T cells using lenalidomide-controlled membrane-bound degradable IL-7

使用来那度胺控制的膜结合可降解IL-7对car-t细胞中的细胞因子信号进行化学遗传控制

LEUKEMIA
IF13.4
2023-12-201
PRE
Kann, Michael C.; Schneider, Emily M.; Almazan, Antonio J.; Lane, Isabel C.; Bouffard, Amanda A.; Supper, Valentina M.; Takei, Hana N.; Tepper, Alexander; Leick, Mark B.; Larson, Rebecca C.; Ebert, Benjamin L.; Maus, Marcela V.; Jan, Max
Clonal hematopoiesis is associated with protection from Alzheimer's disease

克隆造血与阿尔茨海默病的保护有关

NATURE MEDICINE
IF50
2023-06-1539
OAAI
Bouzid, Hind; Belk, Julia A.; Jan, Max; Qi, Yanyan; Sarnowski, Chloe; Wirth, Sara; Ma, Lisa; Chrostek, Matthew R.; Ahmad, Herra; Nachun, Daniel; Yao, Winnie; Beiser, Alexa; Bick, Alexander G.; Bis, Joshua C.; Fornage, Myriam; Longstreth, William T., Jr.; Lopez, Oscar L.; Natarajan, Pradeep; Psaty, Bruce M.; Satizabal, Claudia L.; Weinstock, Joshua; Larson, Eric B.; Crane, Paul K.; Keene, C. Dirk; Seshadri, Sudha; Satpathy, Ansuman T.; Montine, Thomas J.; Jaiswal, Siddhartha
Distinct cellular dynamics associated with response to CAR-T therapy for refractory B cell lymphoma

与难治性b细胞淋巴瘤car-t治疗反应相关的独特细胞动力学

NATURE MEDICINE
IF50
2022-09-12116
OA
Haradhvala, Nicholas J.; Leick, Mark B.; Maurer, Katie; Gohil, Satyen H.; Larson, Rebecca C.; Yao, Ning; Gallagher, Kathleen M. E.; Katsis, Katelin; Frigault, Matthew J.; Southard, Jackson; Li, Shuqiang; Kann, Michael C.; Silva, Harrison; Jan, Max; Rhrissorrakrai, Kahn; Utro, Filippo; Levovitz, Chaya; Jacobs, Raquel A.; Slowik, Kara; Danysh, Brian P.; Livak, Kenneth J.; Parida, Laxmi; Ferry, Judith; Jacobson, Caron; Wu, Catherine J.; Getz, Gad; Maus, Marcela, V
Calreticulin mutant myeloproliferative neoplasms induce MHC-I skewing, which can be overcome by an optimized peptide cancer vaccine

钙网蛋白突变体骨髓增生性肿瘤诱导mhc-i偏斜，这可以通过优化的肽癌症疫苗来克服

SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2022-06-1512
PRE
Gigoux, Mathieu; Holmstrom, Morten O.; Zappasodi, Roberta; Park, Joseph J.; Pourpe, Stephane; Bozkus, Cansu Cimen; Mangarin, Levi M. B.; Redmond, David; Verma, Svena; Schad, Sara; George, Mariam M.; Venkatesh, Divya; Ghosh, Arnab; Hoyos, David; Molvi, Zaki; Kamaz, Baransel; Marneth, Anna E.; Duke, William; Leventhal, Matthew J.; Jan, Max; Ho, Vincent T.; Hobbs, Gabriela S.; Knudsen, Trine Alma; Skov, Vibe; Kjaer, Lasse; Larsen, Thomas Stauffer; Hansen, Dennis Lund; Lindsley, R. Coleman; Hasselbalch, Hans; Grauslund, Jacob H.; Lisle, Thomas L.; Met, Ozcan; Wilkinson, Patrick; Greenbaum, Benjamin; Sepulveda, Manuel A.; Chan, Timothy; Rampal, Raajit; Andersen, Mads H.; Abdel-Wahab, Omar; Bhardwaj, Nina; Wolchok, Jedd D.; Mullally, Ann; Merghoub, Taha
Reversible ON- and OFF-switch chimeric antigen receptors controlled by lenalidomide
SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2021-01-06178
OA
Jan, Max; Scarfo, Irene; Larson, Rebecca C.; Walker, Amanda; Schmidts, Andrea; Guirguis, Andrew A.; Gasser, Jessica A.; Slabicki, Mikolaj; Bouffard, Amanda A.; Castano, Ana P.; Kann, Michael C.; Cabral, Maria L.; Tepper, Alexander; Grinshpun, Daniel E.; Sperling, Adam S.; Kyung, Taeyoon; Sievers, Quinlan L.; Birnbaum, Michael E.; Maus, Marcela, V; Ebert, Benjamin L.
MHC-I SKEWING IN MUTANT CALRETICULIN-POSITIVE MYELOPROLIFERATIVE NEOPLASMS IS COUNTERED BY HETEROCLITIC PEPTIDE CANCER VACCINATION
JOURNAL FOR IMMUNOTHERAPY OF CANCER
IF10.6
2020-11-090
OAAI
Gigoux, Mathieu; Zappasodi, Roberta; Park, Joseph; Pourpe, Stephane; Ghosh, Arnab; Bozkus, Cansu Cimen; Mangarin, Levi; Redmond, David; Verma, Svena; Schad, Sara; Duke, William; Jan, Max; Leventhal, Matthew; Ho, Vincent; Hobbs, Gabriela; Knudsen, Trine Alma; Skov, Vibe; Kjaer, Lasse; Larsen, Thomas Stauffer; Hansen, Dennis Lund; Lindsley, R. Coleman; Hasselbalch, Hans; Grauslund, Jacob; Andersen, Mads; Holmstrom, Morten; Chan, Timothy; Rampal, Raajit; Abdel-Wahab, Omar; Bhardwaj, Nina; Wolchok, Jedd; Mullally, Ann; Merghoub, Taha
Recurrent genetic HLA loss in AML relapsed after matched unrelated allogeneic hematopoietic cell transplantation
BLOOD ADVANCES
IF7.1
2019-07-1956
OA
Jan, Max; Leventhal, Matthew J.; Morgan, Elizabeth A.; Wengrod, Jordan C.; Nag, Anwesha; Drinan, Samantha D.; Wollison, Bruce M.; Ducar, Matthew D.; Thorner, Aaron R.; Leppanen, Scott; Baronas, Jane; Stevens, Jonathan; Lane, William J.; Kekre, Natasha; Ho, Vincent T.; Koreth, John; Cutler, Corey S.; Nikiforow, Sarah; Alyea, Edwin P., III; Antin, Joseph H.; Soiffer, Robert J.; Ritz, Jerome; Lindsley, R. Coleman; Ebert, Benjamin L.
COPA mutations impair ER-Golgi transport and cause hereditary autoimmune-mediated lung disease and arthritis
NATURE GENETICS
IF31.8
2015-04-20272
OAAI
Watkin, Levi B.; Jessen, Birthe; Wiszniewski, Wojciech; Vecel, Timothy J.; Jan, Max; Sha, Youbao; Thamsen, Maike; Santos-Cortez, Regie L. P.; Lee, Kwanghyuk; Gambint, Tomasz; Forbes, Lisa R.; Law, Christopher S.; Stray-Pedersenzt, Asbjorg; Cheng, Mickie H.; Mace, Emily M.; Anderson, Mark S.; Liu, Dongfang; Tang, Ling Fung; Nicholas, Sarah K.; Nahmod, Karen; Makedonas, George; Canter, Debra L.; Kwok, Pui-Yan; Hicks, John; Jones, Kirk D.; Penney, Samantha; Jhangiani, Shalini N.; Rosenblum, Michael D.; Dell, Sharon D.; Waterfield, Michael R.; Papa, Feroz R.; Muzny, Donna M.; Zaitlen, Noah; Leal, Suzanne M.; Gonzaga-Jaureguit, Claudia; Boerwinkle, Eric; Eissa, N. Tony; Gibbs, Richard A.; Lupski, James R.; Orange, Jordan S.; Shum, Anthony K.

研究方向

暂未获取到该数据
M
Marcela V. Maus
H 指数:84论文数:512被引数:3.3万
B
Benjamin L. Ebert
H 指数:122论文数:775被引数:15.5万
M
Mark B. Leick
H 指数:22论文数:164被引数:3,681
M
Michael C. Kann
H 指数:14论文数:103被引数:1,439
A
Amanda A. Bouffard
H 指数:16论文数:136被引数:2,462
I
Irving L. Weissman
H 指数:215论文数:1,318被引数:19.2万
R
Ravindra Majeti
H 指数:71论文数:506被引数:3.0万
R
Rebecca C. Larson
H 指数:26论文数:136被引数:4,908
I
Isabel C. Lane
H 指数:3论文数:10被引数:24
A
Adam S. Sperling
H 指数:34论文数:331被引数:6,023