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E

Esther Pérez-Herrán

Tres Cantos
H指数:30
被引数:3,889

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Alpibectir–Ethionamide combination (AlpE) for the treatment of tuberculosis

Alpibectir–Ethionamide组合（AlpE）用于治疗结核病

Nature Communications
IF15.7
2026-04-070
OAAI
Zainab Edoo; Camille Grosse; Thomas Maitre; Rosangela Frita; Aurélie Chauffour; Laure Fournier Le Ray; Alexandre Godmer; Alexandra Aubry; Marilyne Bourotte; Rudy Antoine; Lina Tawk; Stéphanie Slupek; Vincent Trebosc; Birgit Schellhorn; Aurore Dreneau; Line Hofmann; Christian Kemmer; Sergio Lociuro; Glenn E. Dale; Françoise Jung; Esther Pérez-Herrán; Alfonso Mendoza; Maria Jose Rebollo López; Sonja Ghidelli-Disse; Thilo Werner; Lluis Ballell; David Barros-Aguirre; Vanessa Mathys; Karine Soetaert; Véronique Megalizzi; René Wintjens; Marc Gitzinger; Benoit Deprez; Nicolas Veziris; Modesto J. Remuiñán; Nicolas Willand; Michel Pieren; Alain R. Baulard
Preserved efficacy of lyophilized SARS-CoV-2 mRNA vaccine incorporating novel ionizable lipids after one year at 25 °C

在25 °C条件下储存一年后，采用新型可电离脂质包封的冻干SARS-CoV-2 mRNA疫苗仍保持有效。

npj Vaccines
IF6.5
2025-07-010
OAAI
Elena Mata; Esther Broset; Carlos Matute; Andrei Stoian; Susana Adame; Teresa Alejo; Alexandre López; Beatriz Andrés; Juan Heredero; Diego de Miguel; Javier Giménez-Warren; Verónica Lampaya; Diego Casabona; Alba Calvo; Gema Quincoces; Iván Peñuelas; Carlos Gamazo; Iratxe Uranga; Natacha Peña; Maykel Arias; Julián Pardo; Bernardino Moreno; Juan Badiola; Juan Martínez-Oliván; Esther Pérez-Herrán
Sanfetrinem, an oral (3-lactam antibiotic repurposed for the treatment of tuberculosis

Sanfetrinem，一种用于治疗结核病的口服β-内酰胺类抗生素。

DRUG RESISTANCE UPDATES
IF21.7
2025-05-010
OAAI
Ramon-Garcia, Santiago; del Rio, Ruben Gonzalez; Arenaz-Callao, Maria Pilar; Boshoff, Helena I.; Rullas, Joaquin; Anca, Sara; Izquierdo, Monica Cacho; de Francisco, Esther Porras; Herran, Esther Perez; Santos-Villarejo, Angel; Mendoza-Losana, Alfonso; Ferrer-Bazaga, Santiago; Thompson, Charles J.; Aguirre, David Barros; Bates, Robert H.
Lysyl-tRNA synthetase, a target for urgently needed M. tuberculosis drugs
NATURE COMMUNICATIONS
IF15.7
2022-10-1113
OAAI
Green, Simon R.; Davis, Susan H.; Damerow, Sebastian; Engelhart, Curtis A.; Mathieson, Michael; Baragana, Beatriz; Robinson, David A.; Tamjar, Jevgenia; Dawson, Alice; Tamaki, Fabio K.; Buchanan, Kirsteen, I; Post, John; Dowers, Karen; Shepherd, Sharon M.; Jansen, Chimed; Zuccotto, Fabio; Gilbert, Ian H.; Epemolu, Ola; Riley, Jennifer; Stojanovski, Laste; Osuna-Cabello, Maria; Perez-Herran, Esther; Rebollo, Maria Jose; Lopez, Laura Guijarro; Castro, Patricia Casado; Camino, Isabel; Kim, Heather C.; Bean, James M.; Nahiyaan, Navid; Rhee, Kyu Y.; Wang, Qinglan; Tan, Vee Y.; Boshoff, Helena I. M.; Converse, Paul J.; Li, Si-Yang; Chang, Yong S.; Fotouhi, Nader; Upton, Anna M.; Nuermberger, Eric L.; Schnappinger, Dirk; Read, Kevin D.; Encinas, Lourdes; Bates, Robert H.; Wyatt, Paul G.; Cleghorn, Laura A. T.
GSK2556286 Is a Novel Antitubercular Drug Candidate Effective In Vivo with the Potential To Shorten Tuberculosis Treatment
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
2022-06-2128
OA
Nuermberger, Eric L.; Martinez-Martinez, Maria Santos; Sanz, Olalla; Urones, Beatriz; Esquivias, Jorge; Soni, Heena; Tasneen, Rokeya; Tyagi, Sandeep; Li, Si-Yang; Converse, Paul J.; Boshoff, Helena I.; Robertson, Gregory T.; Besra, Gurdyal S.; Abrahams, Katherine A.; Upton, Anna M.; Mdluli, Khisimuzi; Boyle, Gary W.; Turner, Sam; Fotouhi, Nader; Cammack, Nicholas C.; Siles, Juan Miguel; Alonso, Marta; Escribano, Jaime; Lelievre, Joel; Rullas-Trincado, Joaquin; Perez-Herran, Esther; Bates, Robert H.; Maher-Edwards, Gareth; Barros, David; Ballell, Lluis; Jimenez, Elena
The small-molecule SMARt751 reverses Mycobacterium tuberculosis resistance to ethionamide in acute and chronic mouse models of tuberculosis

小分子SMARt751在急性和慢性结核病小鼠模型中逆转结核分枝杆菌对乙硫酰胺的耐药性

SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2022-05-0419
OA
Flipo, Marion; Frita, Rosangela; Bourotte, Marilyne; Martinez-Martinez, Maria S.; Boesche, Markus; Boyle, Gary W.; Derimanov, Geo; Drewes, Gerard; Gamallo, Pablo; Ghidelli-Disse, Sonja; Gresham, Stephanie; Jimenez, Elena; de Mercado, Jaime; Perez-Herran, Esther; Porras-De Francisco, Esther; Rullas, Joaquin; Casado, Patricia; Leroux, Florence; Piveteau, Catherine; Kiass, Mehdi; Mathys, Vanessa; Soetaert, Karine; Megalizzi, Veronique; Tanina, Abdalkarim; Wintjens, Rene; Antoine, Rudy; Brodin, Priscille; Delorme, Vincent; Moune, Martin; Djaout, Kamel; Slupek, Stephanie; Kemmer, Christian; Gitzinger, Marc; Ballell, Lluis; Mendoza-Losana, Alfonso; Lociuro, Sergio; Deprez, Benoit; Barros-Aguirre, David; Remuinan, Modesto J.; Willand, Nicolas; Baulard, Alain R.
Inhibiting the stringent response blocks Mycobacterium tuberculosis entry into quiescence and reduces persistence
SCIENCE ADVANCES
IF12.5
2019-03-0196
OAAI
Dutta, Noton K.; Klinkenberg, Lee G.; Vazquez, Maria-Jesus; Segura-Carro, Delfina; Colmenarejo, Gonzalo; Ramon, Fernando; Rodriguez-Miquel, Beatriz; Mata-Cantero, Lydia; Porras-De Francisco, Esther; Chuang, Yu-Min; Rubin, Harvey; Lee, Jae Jin; Eoh, Hyungjin; Bader, Joel S.; Perez-Herran, Esther; Mendoza-Losana, Alfonso; Karakousis, Petros C.
Easy-To-Synthesize Spirocyclic Compounds Possess Remarkable in Vivo Activity against Mycobacterium tuberculosis
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2018-11-2022
OAAI
Guardia, Ana; Baiget, Jessica; Cacho, Monica; Perez, Arancha; Ortega-Guerra, Montserrat; Nxumalo, Winston; Khanye, Setshaba D.; Rullas, Joaquin; Ortega, Fatima; Jimenez, Elena; Perez-Herran, Esther; Fraile-Gabaldon, Maria Teresa; Esquivias, Jorge; Fernandez, Raquel; Porras-De Francisco, Esther; Encinas, Lourdes; Alonso, Marta; Giordano, Ilaria; Rivero, Cristina; Miguel-Siles, Juan; Osende, Javier G.; Badiola, Katrina A.; Rutledge, Peter J.; Todd, Matthew H.; Remuinan, Modesto; Alemparte, Carlos
Discovery of a Potent and Specific M-tuberculosis Leucyl-tRNA Synthetase Inhibitor: (S)-3-(Aminomethyl)-4-chloro-7-(2hydroxyethoxy)benzo[c][1,2]oxaborol-1(3H)-ol (GSK656)
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2017-09-27133
PREAI
Li, Xianfeng; Hernandez, Vincent; Rock, Fernando L.; Choi, Wai; Mak, Yvonne S. L.; Mohan, Manisha; Mao, Weimin; Zhou, Yasheen; Easom, Eric E.; Plattner, Jacob J.; Zou, Wuxin; Perez-Herran, Esther; Giordano, Ilaria; Mendoza-Losana, Alfonso; Alemparte, Carlos; Rullas, Joaquin; Angulo-Barturen, Inigo; Crouch, Sabrinia; Ortega, Fatima; Barros, David; Alley, M. R. K.
Discovery of Novel Oral Protein Synthesis Inhibitors of Mycobacterium tuberculosis That Target Leucyl-tRNA Synthetase
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
2016-10-0199
OAAI
Palencia, Andres; Li, Xianfeng; Bu, Wei; Choi, Wai; Ding, Charles Z.; Easom, Eric E.; Feng, Lisa; Hernandez, Vincent; Houston, Paul; Liu, Liang; Meewan, Maliwan; Mohan, Manisha; Rock, Fernando L.; Sexton, Holly; Zhang, Suoming; Zhou, Yasheen; Wan, Baojie; Wang, Yuehong; Franzblau, Scott G.; Woolhiser, Lisa; Gruppo, Veronica; Lenaerts, Anne J.; O'Malley, Theresa; Parish, Tanya; Cooper, Christopher B.; Waters, M. Gerard; Ma, Zhenkun; Ioerger, Thomas R.; Sacchettini, James C.; Rullas, Joaquin; Angulo-Barturen, Inigo; Perez-Herran, Esther; Mendoza, Alfonso; Barros, David; Cusack, Stephen; Plattner, Jacob J.; Alley, M. R. K.

研究方向

暂未获取到该数据
L
Lluís Ballell
H 指数:38论文数:99被引数:3,989
A
Alfonso Mendoza-Losana
H 指数:19论文数:40被引数:1,449
J
Joaquín Rullás
H 指数:26论文数:61被引数:2,037
D
David Barros
H 指数:27论文数:72被引数:2,312
Í
Íñigo Angulo‐Barturen
H 指数:44论文数:109被引数:6,959
M
Modesto J. Remuiñán
H 指数:16论文数:31被引数:955
G
Gurdyal S. Besra
H 指数:113论文数:676被引数:4.2万
D
David Barros-Aguirre
H 指数:18论文数:32被引数:893
A
A.C. Guardia
H 指数:11论文数:21被引数:377
E
Elena Jiménez
H 指数:14论文数:22被引数:727