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D

David Barros

GlaxoSmithKline
H指数:27
被引数:2,312

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荣誉奖项

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GSK2556286 Is a Novel Antitubercular Drug Candidate Effective In Vivo with the Potential To Shorten Tuberculosis Treatment
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
2022-06-2128
OA
Nuermberger, Eric L.; Martinez-Martinez, Maria Santos; Sanz, Olalla; Urones, Beatriz; Esquivias, Jorge; Soni, Heena; Tasneen, Rokeya; Tyagi, Sandeep; Li, Si-Yang; Converse, Paul J.; Boshoff, Helena I.; Robertson, Gregory T.; Besra, Gurdyal S.; Abrahams, Katherine A.; Upton, Anna M.; Mdluli, Khisimuzi; Boyle, Gary W.; Turner, Sam; Fotouhi, Nader; Cammack, Nicholas C.; Siles, Juan Miguel; Alonso, Marta; Escribano, Jaime; Lelievre, Joel; Rullas-Trincado, Joaquin; Perez-Herran, Esther; Bates, Robert H.; Maher-Edwards, Gareth; Barros, David; Ballell, Lluis; Jimenez, Elena
Discovery of a Potent and Specific M-tuberculosis Leucyl-tRNA Synthetase Inhibitor: (S)-3-(Aminomethyl)-4-chloro-7-(2hydroxyethoxy)benzo[c][1,2]oxaborol-1(3H)-ol (GSK656)
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2017-09-27133
PREAI
Li, Xianfeng; Hernandez, Vincent; Rock, Fernando L.; Choi, Wai; Mak, Yvonne S. L.; Mohan, Manisha; Mao, Weimin; Zhou, Yasheen; Easom, Eric E.; Plattner, Jacob J.; Zou, Wuxin; Perez-Herran, Esther; Giordano, Ilaria; Mendoza-Losana, Alfonso; Alemparte, Carlos; Rullas, Joaquin; Angulo-Barturen, Inigo; Crouch, Sabrinia; Ortega, Fatima; Barros, David; Alley, M. R. K.
A Phenotypic Based Target Screening Approach Delivers New Antitubercular CTP Synthetase Inhibitors

基于表型的靶标筛选方法提供了新的抗结核CTP合成酶抑制剂

ACS INFECTIOUS DISEASES
IF3.8
2017-05-1129
PREAI
Esposito, Marta; Szadocka, Sara; Degiacomi, Giulia; Orena, Beatrice S.; Mori, Giorgia; Piano, Valentina; Boldrin, Francesca; Zemanova, Julia; Huszar, Stanislav; Barros, David; Ekins, Sean; Lelievre, Joel; Manganelli, Riccardo; Mattevi, Andrea; Pasca, Maria Rosalia; Riccardi, Giovanna; Ballel, Lluis; Mikusova, Katarina; Chiarelli, Laurent R.
Discovery of Novel Oral Protein Synthesis Inhibitors of Mycobacterium tuberculosis That Target Leucyl-tRNA Synthetase
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
2016-10-0199
OAAI
Palencia, Andres; Li, Xianfeng; Bu, Wei; Choi, Wai; Ding, Charles Z.; Easom, Eric E.; Feng, Lisa; Hernandez, Vincent; Houston, Paul; Liu, Liang; Meewan, Maliwan; Mohan, Manisha; Rock, Fernando L.; Sexton, Holly; Zhang, Suoming; Zhou, Yasheen; Wan, Baojie; Wang, Yuehong; Franzblau, Scott G.; Woolhiser, Lisa; Gruppo, Veronica; Lenaerts, Anne J.; O'Malley, Theresa; Parish, Tanya; Cooper, Christopher B.; Waters, M. Gerard; Ma, Zhenkun; Ioerger, Thomas R.; Sacchettini, James C.; Rullas, Joaquin; Angulo-Barturen, Inigo; Perez-Herran, Esther; Mendoza, Alfonso; Barros, David; Cusack, Stephen; Plattner, Jacob J.; Alley, M. R. K.
Identification of KasA as the cellular target of an anti-tubercular scaffold
NATURE COMMUNICATIONS
IF15.7
2016-09-0176
OAAI
Abrahams, Katherine A.; Chung, Chun-wa; Ghidelli-Disse, Sonja; Rullas, Joaquin; Jose Rebollo-Lopez, Maria; Gurcha, Sudagar S.; Cox, Jonathan A. G.; Mendoza, Alfonso; Jimenez-Navarro, Elena; Santos Martinez-Martinez, Maria; Neu, Margarete; Shillings, Anthony; Homes, Paul; Argyrou, Argyrides; Casanueva, Ruth; Loman, Nicholas J.; Moynihan, Patrick J.; Lelievre, Joel; Selenski, Carolyn; Axtman, Matthew; Kremer, Laurent; Bantscheff, Marcus; Angulo-Barturen, Inigo; Cacho Izquierdo, Monica; Cammack, Nicholas C.; Drewes, Gerard; Ballell, Lluis; Barros, David; Besra, Gurdyal S.; Bates, Robert H.
Antitubercular drugs for an old target: GSK693 as a promising InhA direct inhibitor
EBIOMEDICINE
IF10.8
2016-06-0169
OAAI
Martinez-Hoyos, Maria; Perez-Herran, Esther; Gulten, Gulcin; Encinas, Lourdes; Alvarez-Gomez, Daniel; Alvarez, Emilio; Ferrer-Bazaga, Santiago; Garcia-Perez, Adolfo; Ortega, Fatima; Angulo-Barturen, Inigo; Rullas-Trincado, Joaquin; Blanco Ruano, Delia; Torres, Pedro; Castaneda, Pablo; Huss, Sophie; Fernandez Menendez, Raquel; Gonzalez del Valle, Silvia; Ballell, Lluis; Barros, David; Modha, Sundip; Dhar, Neeraj; Signorino-Gelo, Francois; McKinney, John D.; Francisco Garcia-Bustos, Jose; Lavandera, Jose Luis; Sacchettini, James C.; Soledad Jimenez, M.; Martin-Casabona, Nuria; Castro-Pichel, Julia; Mendoza-Losana, Alfonso
New direct inhibitors of InhA with antimycobacterial activity based on a tetrahydropyran scaffold
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
2016-04-0128
PREAI
Pajk, Stane; Zivec, Matej; Sink, Roman; Sosic, Izidor; Neu, Margarete; Chung, Chun-wa; Martinez-Hoyos, Maria; Perez-Herran, Esther; Alvarez-Gomez, Daniel; Alvarez-Ruiz, Emilio; Mendoza-Losana, Alfonso; Castro-Pichel, Julia; Barros, David; Ballell-Pages, Lluis; Young, Robert J.; Convery, Maire A.; Encinas, Lourdes; Gobec, Stanislav

研究方向

暂未获取到该数据
L
Lluís Ballell
H 指数:38论文数:99被引数:3,989
E
Esther Pérez‐Herrán
H 指数:30论文数:59被引数:3,889
Í
Íñigo Angulo‐Barturen
H 指数:44论文数:109被引数:6,959
A
Alfonso Mendoza-Losana
H 指数:19论文数:40被引数:1,449
R
Robert H. Bates
H 指数:56论文数:409被引数:1.5万
J
Joël Lelièvre
H 指数:28论文数:56被引数:2,484
J
Joaquín Rullás
H 指数:26论文数:61被引数:2,037
J
José Luís Lavandera
H 指数:17论文数:49被引数:1,194
G
Gurdyal S. Besra
H 指数:113论文数:676被引数:4.2万
K
Katherine A. Abrahams
H 指数:15论文数:27被引数:1,089