Kenneth Ngo

dana farber cancer institute

H指数:13

被引数:1,143

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TRI-611, a selective, brain-penetrant molecular glue degrader of ALK

TRI-611，一种选择性、可透过血脑屏障的ALK分子胶降解剂

Nature

IF48.5

2026-09-090

PRE

PTPN2 inhibition unleashes response to STING agonism in head and neck squamous cell cancer

PTPN2抑制在头颈鳞状细胞癌中释放对STING激动剂的反应

Nature Communications

IF15.7

2026-05-020

OAAI

Cyclin A/B RxL Macrocyclic Inhibitors to Treat Cancers with High E2F Activity

Cyclin A/B RxL 环状大环抑制剂用于治疗高 E2F 活性癌症

Journal of Thoracic Oncology

IF20.8

2025-08-290

PRE

Shilpa Singh; Catherine E. Gleason; Min Fang; Yasmin N. Laimon; Vishal Khivansara; Shanhai Xie; Yavuz T. Durmaz; Aniruddha Sarkar; Kenneth Ngo; Varunika Savla; Yixiang Li; Muhannad Abu-Remaileh; Xinyue Li; Bishma Tuladhar; Ranya Odeh; Frances Hamkins-Indik; Daphne He; Miles W. Membreno; Meisam Nosrati; Nathan N. Gushwa; Siegfried S.F. Leung; Breena Fraga-Walton; Luis Hernandez; Miguel P. Baldomero; Bryan M. Lent; David Spellmeyer; Joshua F. Luna; Dalena Hoang; Yuliana Gritsenko; Manesh Chand; Megan K. DeMart; Sammy Metobo; Chinmay Bhatt; Justin A. Shapiro; Kai Yang; Nathan J. Dupper; Andrew T. Bockus; John G. Doench; James B. Aggen; Li-Fen Liu; Bernard Levin; Evelyn W. Wang; Iolanda Vendrell; Roman Fischer; Benedikt Kessler; Prafulla C. Gokhale; Sabina Signoretti; Alexander Spektor; Constantine Kreatsoulas; Rajinder Singh; David J. Earp; Pablo D. Garcia; Deepak Nijhawan; Matthew G. Oser

Targeting G1–S-checkpoint-compromised cancers with cyclin A/B RxL inhibitors

靶向G1-S检验点受损的癌症，使用细胞周期蛋白A/B RxL抑制剂

Nature

IF48.5

2025-08-200

Shilpa Singh; Catherine E. Gleason; Min Fang; Yasmin N. Laimon; Vishal Khivansara; Shanhai Xie; Yavuz T. Durmaz; Aniruddha Sarkar; Kenneth Ngo; Varunika Savla; Yixiang Li; Muhannad Abu-Remaileh; Xinyue Li; Marie-Anais Locquet; Bishma Tuladhar; Ranya Odeh; Frances Hamkins-Indik; Daphne He; Miles W. Membreno; Meisam Nosrati; Nathan N. Gushwa; Siegfried S. F. Leung; Breena Fraga-Walton; Luis Hernandez; Miguel P. Baldomero; Bryan M. Lent; David Spellmeyer; Joshua F. Luna; Dalena Hoang; Yuliana Gritsenko; Manesh Chand; Megan K. DeMart; Sammy Metobo; Chinmay Bhatt; Justin A. Shapiro; Kai Yang; Nathan J. Dupper; Andrew T. Bockus; Jinshu Fang; Ramesh Bambal; Peadar Cremin; John G. Doench; James B. Aggen; Li-Fen Liu; Bernard Levin; Evelyn W. Wang; Iolanda Vendrell; Roman Fischer; Benedikt Kessler; Prafulla C. Gokhale; Sabina Signoretti; Alexander Spektor; Constantine Kreatsoulas; Marie Evangelista; Rajinder Singh; David J. Earp; Deepak Nijhawan; Pablo D. Garcia; Matthew G. Oser

Cotargeting a MYC/eIF4A-survival axis improves the efficacy of KRAS inhibitors in lung cancer

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2023-08-158

OAAI

Treating Upper Limb Spasticity With OnabotulinumtoxinA: Subgroup Analysis of US Practice Patterns From the ASPIRE Study

NEUROLOGY

IF8.5

2023-04-250

PRE

Oncogenic switch and single-agent MET inhibitor sensitivity in a subset of EGFR-mutant lung cancer

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2021-09-0114

OAAI

Eser, Pinar Ozden; Paranal, Raymond M.; Son, Jieun; Ivanova, Elena; Kuang, Yanan; Haikala, Heidi M.; To, Ciric; Okoro, Jeffrey J.; Dholakia, Kshiti H.; Choi, Jihyun; Eum, Yoonji; Ogino, Atsuko; Missios, Pavlos; Ercan, Dalia; Xu, Man; Poitras, Michael J.; Wang, Stephen; Ngo, Kenneth; Dills, Michael; Yanagita, Masahiko; Lopez, Timothy; Lin, Mika; Tsai, Jeanelle; Floch, Nicolas; Chambers, Emily S.; Heng, Jennifer; Anjum, Rana; Santucci, Alison D.; Michael, Kesi; Schuller, Alwin G.; Cross, Darren; Smith, Paul D.; Oxnard, Geoffrey R.; Barbie, David A.; Sholl, Lynette M.; Bahcall, Magda; Palakurthi, Sangeetha; Gokhale, Prafulla C.; Paweletz, Cloud P.; Daley, George Q.; Janne, Pasi A.

Acute pharmacological degradation of Helios destabilizes regulatory T cells

NATURE CHEMICAL BIOLOGY

IF13.7

2021-05-2564

OAAI

Intense Arm Rehabilitation Therapy Improves the Modified Rankin Scale Score Association Between Gains in Impairment and Function

NEUROLOGY

IF8.5

2021-04-0615