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收藏分享 收藏 Runx1t1 is an epigenetic regulator essential for MYCN-driven neuroblastoma tumorigenesis
Norris, M.; Murray, J.; Valli, E.; Milazzo, G.; Mayoh, C.; Gifford, A.; Fletcher, J.; Xue, C.; Jayatilleke, N.; Gamble, L.; De Rosa, P.; Marshall, G.; Giorgi, F.; Koster, J.; Perini, G.; Haber, M. 分享 收藏 The transcriptional co-repressor Runx1t1 is essential for MYCN-driven neuroblastoma tumorigenesis转录共阻遏物Runx1t1对于MYCN驱动的神经母细胞瘤肿瘤发生至关重要Murray, Jayne E.; Valli, Emanuele; Milazzo, Giorgio; Mayoh, Chelsea; Gifford, Andrew J.; Fletcher, Jamie I.; Xue, Chengyuan; Jayatilleke, Nisitha; Salehzadeh, Firoozeh; Gamble, Laura D.; Rouaen, Jourdin R. C.; Carter, Daniel R.; Forgham, Helen; Sekyere, Eric O.; Keating, Joanna; Eden, Georgina; Allan, Sophie; Alfred, Stephanie; Kusuma, Frances K.; Clark, Ashleigh; Webber, Hannah; Russell, Amanda J.; de Weck, Antoine; Kile, Benjamin T.; Santulli, Martina; De Rosa, Piergiuseppe; Fleuren, Emmy D. G.; Gao, Weiman; Wilkinson-White, Lorna; Low, Jason K. K.; Mackay, Joel P.; Marshall, Glenn M.; Hilton, Douglas J.; Giorgi, Federico M.; Koster, Jan; Perini, Giovanni; Haber, Michelle; Norris, Murray D. 分享 收藏 分享 收藏 MYCN-driven fatty acid uptake is a metabolic vulnerability in neuroblastomaTao, Ling; Mohammad, Mahmoud A.; Milazzo, Giorgio; Moreno-Smith, Myrthala; Patel, Tajhal D.; Zorman, Barry; Badachhape, Andrew; Hernandez, Blanca E.; Wolf, Amber B.; Zeng, Zihua; Foster, Jennifer H.; Aloisi, Sara; Sumazin, Pavel; Zu, Youli; Hicks, John; Ghaghada, Ketan B.; Putluri, Nagireddy; Perini, Giovanni; Coarfa, Cristian; Barbieri, Eveline 分享 收藏 CHAF1A Blocks Neuronal Differentiation and Promotes Neuroblastoma Oncogenesis via Metabolic ReprogrammingTao, Ling; Moreno-Smith, Myrthala; Ibarra-Garcia-Padilla, Rodrigo; Milazzo, Giorgio; Drolet, Nathan A.; Hernandez, Blanca E.; Oh, Young S.; Patel, Ivanshi; Kim, Jean J.; Zorman, Barry; Patel, Tajhal; Kamal, Abu Hena Mostafa; Zhao, Yanling; Hicks, John; Vasudevan, Sanjeev A.; Putluri, Nagireddy; Coarfa, Cristian; Sumazin, Pavel; Perini, Giovanni; Parchem, Ronald J.; Uribe, Rosa A.; Barbieri, Eveline 分享 收藏 Restoration of the molecular clock is tumor suppressive in neuroblastomaMoreno-Smith, Myrthala; Milazzo, Giorgio; Tao, Ling; Fekry, Baharan; Zhu, Bokai; Mohammad, Mahmoud A.; Di Giacomo, Simone; Borkar, Roshan; Reddy, Karthik Reddy Kami; Capasso, Mario; Vasudevan, Sanjeev A.; Sumazin, Pavel; Hicks, John; Putluri, Nagireddy; Perini, Giovanni; Eckel-Mahan, Kristin; Burris, Thomas P.; Barbieri, Eveline 分享 收藏 PRDM15 is a key regulator of metabolism critical to sustain B-cell lymphomagenesisPRDM15是维持b细胞淋巴瘤发生的关键代谢调节剂Mzoughi, Slim; Fong, Jia Yi; Papadopoli, David; Koh, Cheryl M.; Hulea, Laura; Pigini, Paolo; Di Tullio, Federico; Andreacchio, Giuseppe; Hoppe, Michal Marek; Wollmann, Heike; Low, Diana; Caldez, Matias J.; Peng, Yanfen; Torre, Denis; Zhao, Julia N.; Uchenunu, Oro; Varano, Gabriele; Motofeanu, Corina-Mihaela; Lakshmanan, Manikandan; Teo, Shun Xie; Wun, Cheng Mun; Perini, Giovanni; Tan, Soo Yong; Ong, Chee Bing; Al-Haddawi, Muthafar; Rajarethinam, Ravisankar; Hue, Susan Swee-Shan; Lim, Soon Thye; Ong, Choon Kiat; Huang, Dachuan; Ng, Siok-Bian; Bernstein, Emily; Hasson, Dan; Wee, Keng Boon; Kaldis, Philipp; Jeyasekharan, Anand; Dominguez-sola, David; Topisirovic, Ivan; Guccione, Ernesto 分享 收藏 分享 收藏 分享 收藏 Repurposing a psychoactive drug for children with cancer: p27Kip1-dependent inhibition of metastatic neuroblastomas by ProzacBibbo', Sandra; Lamolinara, Alessia; Capone, Emily; Purgato, Stefania; Tsakaneli, Alexia; Panella, Valeria; Sallese, Michele; Rossi, Cosmo; Ciufici, Paolo; Nieddu, Valentina; De Laurenzi, Vincenzo; Iezzi, Manuela; Perini, Giovanni; Sala, Gianluca; Sala, Arturo 分享 收藏 The long noncoding RNA lncNB1 promotes tumorigenesis by interacting with ribosomal protein RPL35Liu, Pei Y.; Tee, Andrew E.; Milazzo, Giorgio; Hannan, Katherine M.; Maag, Jesper; Mondal, Sujanna; Atmadibrata, Bernard; Bartonicek, Nenad; Peng, Hui; Ho, Nicholas; Mayoh, Chelsea; Ciaccio, Roberto; Sun, Yuting; Henderson, Michelle J.; Gao, Jixuan; Everaert, Celine; Hulme, Amy J.; Wong, Matthew; Lan, Qing; Cheung, Belamy B.; Shi, Leming; Wang, Jenny Y.; Simon, Thorsten; Fischer, Matthias; Zhang, Xu D.; Marshall, Glenn M.; Norris, Murray D.; Haber, Michelle; Vandesompele, Jo; Li, Jinyan; Mestdagh, Pieter; Hannan, Ross D.; Dinger, Marcel E.; Perini, Giovanni; Liu, Tao 分享 收藏 Drugging MYCN Oncogenic Signaling through the MYCN-PA2G4 Binding InterfaceKoach, Jessica; Holien, Jessica K.; Massudi, Hassina; Carter, Daniel R.; Ciampa, Olivia C.; Herath, Mika; Lim, Taylor; Seneviratne, Janith A.; Milazzo, Giorgio; Murray, Jayne E.; McCarroll, Joshua A.; Liu, Bing; Mayoh, Chelsea; Keenan, Bryce; Stevenson, Brendan W.; Gorman, Michael A.; Bell, Jessica L.; Doughty, Larissa; Huettelmaier, Stefan; Oberthuer, Andre; Fischer, Matthias; Gifford, Andrew J.; Liu, Tao; Zhang, Xiaoling; Zhu, Shizhen; Gustafson, W. Clay; Haber, Michelle; Norris, Murray D.; Fletcher, Jamie I.; Perini, Giovanni; Parker, Michael W.; Cheung, Belamy B.; Marshall, Glenn M. 分享 收藏 JMJD6 is a tumorigenic factor and therapeutic target in neuroblastomaWong, Matthew; Sun, Yuting; Xi, Zhichao; Milazzo, Giorgio; Poulos, Rebecca C.; Bartenhagen, Christoph; Bell, Jessica L.; Mayoh, Chelsea; Ho, Nicholas; Tee, Andrew E.; Chen, Xiaoqiong; Li, Yang; Ciaccio, Roberto; Liu, Pei Y.; Jiang, Chen C.; Lan, Qing; Jayatilleke, Nisitha; Cheung, Belamy B.; Haber, Michelle; Norris, Murray D.; Zhang, Xu D.; Marshall, Glenn M.; Wang, Jenny Y.; Huettelmaier, Stefan; Fischer, Matthias; Wong, Jason W. H.; Xu, Hongxi; Perini, Giovanni; Dong, Qihan; George, Rani E.; Liu, Tao 分享 收藏 A novel iron-chelating agent reduces MYC transcription via E2F gene family regulationValli, Emanuele; Xue, Chengyuan; Cheung, Leanna; Gamble, Laura; Pandher, Ruby; Di Giacomo, Simone; Burkhart, Catherine; Fedtsova, Natalia; Ferrucci, Francesca; Makarov, Sergei; Telfer, Thomas; Codd, Rachel; Scott, David; Perini, Giovanni; Osterman, Andrei; Gudkov, Andrei; Norris, Murray; Haber, Michelle 分享 收藏 Inhibition of polyamine synthesis and uptake reduces tumor progression and prolongs survival in mouse models of neuroblastomaGamble, Laura D.; Purgato, Stefania; Murray, Jayne; Xiao, Lin; Yu, Denise M. T.; Hanssen, Kimberley M.; Giorgi, Federico M.; Carter, Daniel R.; Gifford, Andrew J.; Valli, Emanuele; Milazzo, Giorgio; Kamili, Alvin; Mayoh, Chelsea; Liu, Bing; Eden, Georgina; Sarraf, Sara; Allan, Sophie; Di Giacomo, Simone; Flemming, Claudia L.; Russell, Amanda J.; Cheung, Belamy B.; Oberthuer, Andre; London, Wendy B.; Fischer, Matthias; Trahair, Toby N.; Fletcher, Jamie, I; Marshall, Glenn M.; Ziegler, David S.; Hogarty, Michael D.; Burns, Mark R.; Perini, Giovanni; Norris, Murray D.; Haber, Michelle 分享 收藏 A new BCR-ABL1 Drosophila model as a powerful tool to elucidate the pathogenesis and progression of chronic myeloid leukemiaBernardoni, Roberto; Giordani, Giorgia; Signorino, Elisabetta; Monticelli, Sara; Messa, Francesca; Pradotto, Monica; Rosso, Valentina; Bracco, Enrico; Giangrande, Angela; Perini, Giovanni; Saglio, Giuseppe; Cilloni, Daniela 分享 收藏 Eradication of neuroblastoma by suppressing the expression of a single noncoding RNATee, Andrew E.; Liu, Pei Y.; Milazzo, Giorgio; Hannan, Kate M.; Maag, Jesper; Bartonicek, Nenad; Song, Renhua; Jiang, Chen C.; Zhang, Xu D.; Norris, Murray D.; Haber, Michelle; Marshall, Glenn M.; Li, Jinyan; Vandesompele, Jo; Mattick, John S.; Mestdagh, Pieter; Perini, Giovanni; Hannan, Ross D.; Dinger, Marcel E.; Liu, Tao 分享 收藏 The Hidden Genomic and Transcriptomic Plasticity of Giant Marker Chromosomes in CancerMacchia, Gemma; Severgnini, Marco; Purgato, Stefania; Tolomeo, Doron; Casciaro, Hilen; Cifola, Ingrid; L'Abbate, Alberto; Loverro, Anna; Palumbo, Orazio; Carella, Massimo; Bianchini, Laurence; Perini, Giovanni; De Bellis, Gianluca; Mertens, Fredrik; Rocchi, Mariano; Storlazzi, Clelia Tiziana 分享 收藏 
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