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Laura Patrussi

department of life sciences
H指数:23
被引数:1,939

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Taginostat, a new quinolone-based HDAC6 inhibitor, promotes apoptosis of chronic lymphocytic leukemia cells in vitro and in vivo by activating STAT4

塔吉诺stat,一种新型喹诺酮类HDAC6抑制剂,通过激活STAT4在体外和体内促进慢性淋巴细胞白血病细胞的凋亡

2026-07-040
PRE
IFT20 regulates TFEB-dependent lytic granule biogenesis in cytotoxic T lymphocytes by orchestrating the MPR-dependent transport of granzyme B

IFT20通过协调MPR依赖性的颗粒酶B运输来调控细胞毒性T淋巴细胞中TFEB依赖性的溶酶体颗粒生物发生。

2025-05-190
OA
Activation- induced thrombospondin-4 works with thrombospondin-1 to build cytotoxic supramolecular attack particles

活化诱导的thrombospondin-4与thrombospondin-1协同作用,共同构建细胞毒性超分子攻击颗粒。

2025-02-040
OA
A novel potent class I HDAC inhibitor reverses the STAT4/p66Shc apoptotic defect in B cells from chronic lymphocytic leukemia patients
2024-05-012
OAAI
Leukemic cell-secreted interleukin-9 suppresses cytotoxic T cell-mediated killing in chronic lymphocytic leukemia
2024-02-155
OAAI
Azetidin-2-one-based small molecules as dual hHDAC6/HDAC8 inhibitors: Investigation of their mechanism of action and impact of dual inhibition profile on cell viability
2022-08-0120
PRE
p66Shc deficiency in the Eμ-TCL1 mouse model of chronic lymphocytic leukemia enhances leukemogenesis by altering the chemokine receptor landscape
2019-02-2816
OAAI