Kanagasabai Vadivel - Publications, H-index & Citations

Kanagasabai Vadivel

University of California System

12H指数

33论文数

444被引数

收录论文 12

发表时间

Discovery of an ApoE4-targeted small-molecule SirT1 enhancer for the treatment of Alzheimer's disease 靶向ApoE4的小分子SirT1增强剂的发现及其在阿尔茨海默病治疗中的应用

SCIENTIFIC REPORTS

IF3.9

2025-04-23

OAAI

Campagna, Jesus; Chandra, Sujyoti; Teter, Bruce; Cohn, Whitaker; Pham, Johnny; Kim, Young-Sug; Jagodzinska, Barbara; Vadivel, Kanagasabai; Alam, Parvez; Bilousova, Tina; Young, Malaney; Elias, Chris; Marcucci, Juan; Flacau, Ilinca; Jackman, Ainsley; Padder, Samar; Wi, Dongwook; Zhu, Chunni; Spilman, Patricia; Jung, Michael E.; Bredesen, Dale E.; John, Varghese

Inhibition of a signaling modality within the gp130 receptor enhances tissue regeneration and mitigates osteoarthritis

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2023-03-22

OAAI

Shkhyan, Ruzanna; Flynn, Candace; Lamoure, Emma; Sarkar, Arijita; Van Handel, Benjamin; Li, Jinxiu; York, Jesse; Banks, Nicholas; Van der Horst, Robert; Liu, Nancy Q.; Lee, Siyoung; Bajaj, Paul; Vadivel, Kanagasabai; Harn, Hans I. -Chen; Tassey, Jade; Lozito, Thomas; Lieberman, Jay R.; Chuong, Cheng-Ming; Hurtig, Mark S.; Evseenko, Denis

Enhanced Antifibrinolytic Efficacy of a Plasmin-Specific Kunitz-Inhibitor (60-Residue Y11T/L17R with C-Terminal IEK) of Human Tissue Factor Pathway Inhibitor Type-2 Domain1

JOURNAL OF CLINICAL MEDICINE

IF2.9

2020-11-17

OAAI

Vadivel, Kanagasabai; Zaiss, Anne K.; Kumar, Yogesh; Fabian, Frank M.; Ismail, Ayman E. A.; Arbing, Mark A.; Buchholz, Wallace G.; Velander, William H.; Bajaj, S. Paul

Plasmin-mediated proteolysis of human factor IXa in the presence of calcium/phospholipid: Conversion of procoagulant factor IXa to a fibrinolytic enhancer

JOURNAL OF THROMBOSIS AND HAEMOSTASIS

IF5

2020-05-01

OAAI

Schmidt, Amy E.; Vadivel, Kanagasabai; Whitelegge, Julian; Bajaj, Satya Paul

Dual Neutral Sphingomyelinase-2/Acetylcholinesterase Inhibitors for the Treatment of Alzheimer's Disease

ACS CHEMICAL BIOLOGY

IF3.8

2020-04-30

OAAI

Bilousova, Tina; Simmons, Bryan J.; Knapp, Rachel R.; Elias, Chris J.; Campagna, Jesus; Melnik, Mikhail; Chandra, Sujyoti; Focht, Samantha; Zhu, Chunni; Vadivel, Kanagasabai; Jagodzinska, Barbara; Cohn, Whitaker; Spilman, Patricia; Gylys, Karen H.; Garg, Neil K.; John, Varghese

Sodium-site in serine protease domain of human coagulation factor IXa: evidence from the crystal structure and molecular dynamics simulations study

JOURNAL OF THROMBOSIS AND HAEMOSTASIS

IF5

2019-04-01

OAAI

Vadivel, Kanagasabai; Schreuder, Herman A.; Liesum, Alexander; Schmidt, Amy E.; Goldsmith, Gunaseelan; Bajaj, S. Paul

A Small Molecule Mimetic of the Humanin Peptide as a Candidate for Modulating NMDA-Induced Neurotoxicity

ACS CHEMICAL NEUROSCIENCE

IF3.9

2017-11-21

PREAI

Alam, Mohammad Parvez; Bilousova, Tina; Spilman, Patricia; Vadivel, Kanagasabai; Bai, Dongsheng; Elias, Chris J.; Evseenko, Denis; John, Varghese

S2′-subsite variations between human and mouse enzymes (plasmin, factor XIa, kallikrein) elucidate inhibition differences by tissue factor pathway inhibitor-2 domain1-wild-type, Leu17Arg-mutant and aprotinin

JOURNAL OF THROMBOSIS AND HAEMOSTASIS

IF5

2016-12-01

OAAI

Vadivel, K.; Kumar, Y.; Ogueli, G. I.; Ponnuraj, S. M.; Wongkongkathep, P.; Loo, J. A.; Bajaj, M. S.; Bajaj, S. P.

Platelets Contain Tissue Factor Pathway Inhibitor-2 Derived from Megakaryocytes and Inhibits Fibrinolysis

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2014-11-01

OAAI

Vadivel, Kanagasabai; Ponnuraj, Sathya-Moorthy; Kumar, Yogesh; Zaiss, Anne K.; Bunce, Matthew W.; Camire, Rodney M.; Wu, Ling; Evseenko, Denis; Herschman, Harvey R.; Bajaj, Madhu S.; Bajaj, S. Paul

The heterodimeric structure of heterogeneous nuclear ribonucleoprotein C1/C2 dictates 1,25-dihydroxyvitamin D-directed transcriptional events in osteoblasts

BONE RESEARCH

IF15

2014-07-01

OAAI

Lisse, Thomas S.; Vadivel, Kanagasabai; Bajaj, S. Paul; Zhou, Rui; Chun, Rene F.; Hewison, Martin; Adams, John S.

Structural biology of factor VIIa/tissue factor initiated coagulation

FRONTIERS IN BIOSCIENCE-LANDMARK

IF3.1

2012-01-01

OAAI

Vadivel, Kanagasabai; Bajaj, S. Paul