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C

Catherine H. Régnier

University of Freiburg
H指数:29
被引数:5,023

个人简介

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教育背景

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工作经历

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荣誉奖项

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CD40 blockade hampers IgG class-switch while enhancing Granzyme B production by transitional B cells

CD40阻断抑制IgG类别转换，同时增强过渡型B细胞中Granzyme B的产生

CLINICAL AND EXPERIMENTAL IMMUNOLOGY
IF3.8
2025-01-010
PRE
Werner, Felix; Wittner, Jens; Lehmann, Christian H. K.; Wahlbuhl, Mandy; Allabauer, Ida; Hoffmann, Adrian; Schnell, Alexander; Krickau, Tobias; Hackstein, Holger; Dietel-Schor, Barbara; Rush, James S.; Regnier, Catherine H.; Jack, Hans-Martin; Woelfle, Joachim; Schuh, Wolfgang; Hoerning, Andre
Discovery and development of ANV419, an IL-2/anti-IL-2 antibody fusion protein with potent CD8+T and natural killer cell-stimulating capacity for cancer immunotherapy

ANV419的发现和开发，一种具有有效CD8 T和自然杀伤细胞刺激能力的IL-2/anti-IL-2抗体融合蛋白，用于癌症免疫治疗

MABS
IF7.3
2024-07-230
OAAI
Murer, Patrizia; Brannetti, Barbara; Rondeau, Jean-Michel; Petersen, Laetitia; Egli, Nicole; Popp, Simone; Regnier, Catherine; Richter, Kirsten; Katopodis, Andreas; Huber, Christoph
Single-cell transcriptomic analysis of renal allograft rejection reveals insights into intragraft TCR clonality
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2023-07-1713
OAAI
Shi, Tiffany; Burg, Ashley R.; Caldwell, J. Timothy; Roskin, Krishna M.; Castro-Rojas, Cyd M.; Chukwuma, P. Chukwunalu; Gray, George I.; Foote, Sara G.; Alonso, Jesus A.; Cuda, Carla M.; Allman, David A.; Rush, James S.; Regnier, Catherine H.; Wieczorek, Grazyna; Alloway, Rita R.; Shields, Adele R.; Baker, Brian M.; Woodle, E. Steve; Hildeman, David A.
Discovery of Potent, Highly Selective, and In Vivo Efficacious, Allosteric MALT1 Inhibitors by Iterative Scaffold Morphing
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2020-11-3018
PREAI
Soldermann, Carole Pissot; Simic, Oliver; Renatus, Martin; Erbel, Paulus; Melkko, Samu; Wartmann, Markus; Bigaud, Marc; Weiss, Andreas; McSheehy, Paul; Endres, Ralf; Santos, Paulo; Blank, Jutta; Schuffenhauer, Ansgar; Bold, Guido; Buschmann, Nicole; Zoller, Thomas; Altmann, Eva; Manley, Paul W.; Dix, Ina; Buchdunger, Elisabeth; Scesa, Julien; Quancard, Jean; Schlapbach, Achim; Bornancin, Frederic; Radimerski, Thomas; Regnier, Catherine H.
Optimization of the In Vivo Potency of Pyrazolopyrimidine MALT1 Protease Inhibitors by Reducing Metabolism and Increasing Potency in Whole Blood
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2020-11-2019
PREAI
Quancard, Jean; Simic, Oliver; Soldermann, Carole Pissot; Aichholz, Reiner; Blatter, Markus; Renatus, Martin; Erbel, Paulus; Melkko, Samu; Endres, Ralf; Sorge, Mickael; Kieffer, Laurence; Wagner, Trixie; Beltz, Karen; Mcsheehy, Paul; Wartmann, Markus; Regnier, Catherine H.; Calzascia, Thomas; Radimerski, Thomas; Bigaud, Marc; Weiss, Andreas; Bornancin, Frederic; Schlapbach, Achim
Stabilizing Inactive Conformations of MALT1 as an Effective Approach to Inhibit Its Protease Activity
ADVANCED THERAPEUTICS
IF2.6
2020-06-174
PREAI
Hughes, Nicola; Erbel, Paul; Bornancin, Frederic; Wiesmann, Christian; Schiering, Nikolaus; Villard, Frederic; Decock, Arnaud; Rubi, Bertran; Melkko, Samu; Spanka, Carsten; Buschmann, Nicole; Pissot-Soldermann, Carole; Simic, Oliver; Beerli, Rene; Sorge, Mickael; Tintelnot-Blomley, Marina; Beltz, Karen; Regnier, Catherine H.; Quancard, Jean; Schlapbach, Achim; Langlois, Jean-Baptiste; Renatus, Martin
Requirement of Mucosa-Associated Lymphoid Tissue Lymphoma Translocation Protein 1 Protease Activity for Fcγ Receptor-Induced Arthritis, but Not Fcγ Receptor-Mediated Platelet Elimination, in Mice
ARTHRITIS & RHEUMATOLOGY
IF10.9
2020-04-269
PREAI
Martin, Kea; Touil, Ratiba; Cvijetic, Grozdan; Israel, Laura; Kolb, Yeter; Sarret, Sophie; Valeaux, Stephanie; Degl'Innocenti, Elena; Le Meur, Thomas; Caesar, Nadja; Bardet, Maureen; Beerli, Christian; Zerwes, Hans-Guenter; Kovarik, Jiri; Beltz, Karen; Schlapbach, Achim; Quancard, Jean; Regnier, Catherine H.; Bigaud, Marc; Junt, Tobias; Wieczorek, Grazyna; Isnardi, Isabelle; Littlewood-Evans, Amanda; Bornancin, Frederic; Calzascia, Thomas
The T-cell fingerprint of MALT1 paracaspase revealed by selective inhibition

通过选择性抑制揭示的MALT1 paracaspase的T细胞指纹

IMMUNOLOGY AND CELL BIOLOGY
IF3
2017-12-2153
OAAI
Bardet, Maureen; Unterreiner, Adeline; Malinverni, Claire; Lafossas, Frederique; Vedrine, Corinne; Boesch, Danielle; Kolb, Yeter; Kaiser, Daniel; Gluck, Anton; Schneider, Martin A.; Katopodis, Andreas; Renatus, Martin; Simic, Oliver; Schlapbach, Achim; Quancard, Jean; Regnier, Catherine H.; Bold, Guido; Pissot-Soldermann, Carole; Carballido, Jose M.; Kovarik, Jiri; Calzascia, Thomas; Bornancin, Frederic
Deficiency of MALT1 Paracaspase Activity Results in Unbalanced Regulatory and Effector T and B Cell Responses Leading to Multiorgan Inflammation
JOURNAL OF IMMUNOLOGY
IF3.4
2015-04-15116
OAAI
Bornancin, Frederic; Renner, Florian; Touil, Ratiba; Sic, Heiko; Kolb, Yeter; Touil-Allaoui, Ismahane; Rush, James S.; Smith, Paul A.; Bigaud, Marc; Junker-Walker, Ursula; Burkhart, Christoph; Dawson, Janet; Niwa, Satoru; Katopodis, Andreas; Nuesslein-Hildesheim, Barbara; Weckbecker, Gisbert; Zenke, Gerhard; Kinzel, Bernd; Traggiai, Elisabetta; Brenner, Dirk; Bruestle, Anne; Paul, Michael St.; Zamurovic, Natasa; Mccoy, Kathy D.; Rolink, Antonius; Regnier, Catherine H.; Mak, Tak W.; Ohashi, Pamela S.; Patel, Dhavalkumar D.; Calzascia, Thomas
Modulation of Activation-Loop Phosphorylation by JAK Inhibitors Is Binding Mode Dependent

JAK抑制剂对激活环磷酸化的调节是结合模式依赖性的

CANCER DISCOVERY
IF33.3
2012-06-07114
OA
Andraos, Rita; Qian, Zhiyan; Bonenfant, Debora; Rubert, Joelle; Vangrevelinghe, Eric; Scheufler, Clemens; Marque, Fanny; Regnier, Catherine H.; De Pover, Alain; Ryckelynck, Hugues; Bhagwat, Neha; Koppikar, Priya; Goel, Aviva; Wyder, Lorenza; Tavares, Gisele; Baffert, Fabienne; Pissot-Soldermann, Carole; Manley, Paul W.; Gaul, Christoph; Voshol, Hans; Levine, Ross L.; Sellers, William R.; Hofmann, Francesco; Radimerski, Thomas
Genetic resistance to JAK2 enzymatic inhibitors is overcome by HSP90 inhibition
JOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
2012-01-23138
OAAI
Weigert, Oliver; Lane, Andrew A.; Bird, Liat; Kopp, Nadja; Chapuy, Bjoern; van Bodegom, Diederik; Toms, Angela V.; Marubayashi, Sachie; Christie, Amanda L.; McKeown, Michael; Paranal, Ronald M.; Bradner, James E.; Yoda, Akinori; Gaul, Christoph; Vangrevelinghe, Eric; Romanet, Vincent; Murakami, Masato; Tiedt, Ralph; Ebel, Nicolas; Evrot, Emeline; De Pover, Alain; Regnier, Catherine H.; Erdmann, Dirk; Hofmann, Francesco; Eck, Michael J.; Sallan, Stephen E.; Levine, Ross L.; Kung, Andrew L.; Baffert, Fabienne; Radimerski, Thomas; Weinstock, David M.
Potent and Selective Inhibition of Polycythemia by the Quinoxaline JAK2 Inhibitor NVP-BSK805
MOLECULAR CANCER THERAPEUTICS
IF5.5
2010-07-07113
OAAI
Baffert, Fabienne; Regnier, Catherine H.; De Pover, Alain; Pissot-Soldermann, Carole; Tavares, Gisele A.; Blasco, Francesca; Brueggen, Josef; Chene, Patrick; Drueckes, Peter; Erdmann, Dirk; Furet, Pascal; Gerspacher, Marc; Lang, Marc; Ledieu, David; Nolan, Lynda; Ruetz, Stephan; Trappe, Joerg; Vangrevelinghe, Eric; Wartmann, Markus; Wyder, Lorenza; Hofmann, Francesco; Radimerski, Thomas
Mutations in components of complement influence the outcome of Factor I-associated atypical hemolytic uremic syndrome

补体成分的突变会影响因子I相关的非典型溶血性尿毒症综合征的结果

KIDNEY INTERNATIONAL
IF12.6
2010-02-01159
OAAI
Bienaime, Frank; Dragon-Durey, Marie-Agnes; Regnier, Catherine H.; Nilsson, Sara C.; Kwan, Wing H.; Blouin, Jacques; Jablonski, Mathieu; Renault, Nicolas; Rameix-Welti, Marie-Anne; Loirat, Chantal; Sautes-Fridman, Catherine; Villoutreix, Bruno O.; Blom, Anna M.; Fremeaux-Bacchi, Veronique

研究方向

暂未获取到该数据
F
Frédéric Bornancin
H 指数:33论文数:99被引数:4,484
C
Catherine Tomasetto
H 指数:64论文数:185被引数:1.2万
A
Achim Schlapbach
H 指数:24论文数:61被引数:1,558
C
Carole Pissot‐Soldermann
H 指数:15论文数:43被引数:945
J
Jean Quancard
H 指数:16论文数:43被引数:1,468
T
Thomas Radimerski
H 指数:30论文数:146被引数:5,841
T
Thomas Calzascia
H 指数:25论文数:55被引数:3,009
M
Martin Renatus
H 指数:31论文数:84被引数:6,291
O
Oliver Simić
H 指数:16论文数:48被引数:1,009
M
Markus Wartmann
H 指数:45论文数:208被引数:9,104