Claire Lucas - Publications, H-index & Citations

Claire Lucas

university of liverpool

20H指数

75论文数

2.3K被引数

收录论文 14

发表时间

A Novel CIP2A and BCL-XL Clinical Diagnostic Toolkit to Predict Disease Progression and Treatment-Free Remission in Chronic Myeloid Leukaemia 一种新型CIP2A和BCL-XL临床诊断工具包，用于预测慢性髓系白血病疾病进展和治疗无复发生存期

International Journal of Molecular Sciences

IF4.9

2026-03-01

OAAI

Basabrain, Ammar A.; Austin, Gemma M.; Holcroft, Alison K.; Apperley, Jane F.; Clark, Richard E.; Varadarajan, Shankar; Lucas, Claire M.

SET-PP2A complex as a new therapeutic target in KMT2A (MLL) rearranged AML

ONCOGENE

IF7.3

2023-10-27

OAAI

Di Mambro, Antonella; Arroyo-Berdugo, Yoana; Fioretti, Tiziana; Randles, Michael; Cozzuto, Luca; Rajeeve, Vinothini; Cevenini, Armando; Austin, Michael J.; Esposito, Gabriella; Ponomarenko, Julia; Lucas, Claire M.; Cutillas, Pedro; Gribben, John; Williams, Owen; Calle, Yolanda; Patel, Bela; Esposito, Maria Teresa

Cancerous inhibitor of protein phosphatase 2A (CIP2A) modifies energy metabolism via 5′ AMP-activated protein kinase signalling in malignant cells

BIOCHEMICAL JOURNAL

IF4.3

2019-08-15

PREAI

Austin, James A.; Jenkins, Rosalind E.; Austin, Gemma M.; Glenn, Mark A.; Dunn, Karen; Scott, Laura; Lucas, Claire M.; Clark, Richard E.

Comment on PP2A inhibition sensitizes cancer stem cells to ABL tyrosine kinase inhibitors in BCR-ABL human leukemia

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2019-07-17

OAAI

Perrotti, Danilo; Agarwal, Anupriya; Lucas, Claire M.; Narla, Goutham; Neviani, Paolo; Odero, Maria D.; Ruvolo, Peter P.; Verrills, Nicole M.

CIP2A- and SETBP1-mediated PP2A inhibition reveals AKT S473 phosphorylation to be a new biomarker in AML

BLOOD ADVANCES

IF7.1

2018-04-27

OAAI

Lucas, Claire M.; Scott, Laura J.; Carmell, Natasha; Holcroft, Alison K.; Hills, Robert K.; Burnett, Alan K.; Clark, Richard E.

High CIP2A levels correlate with an antiapoptotic phenotype that can be overcome by targeting BCL-XL in chronic myeloid leukemia

LEUKEMIA

IF13.4

2016-02-29

OAAI

Lucas, C. M.; Milani, M.; Butterworth, M.; Carmell, N.; Scott, L. J.; Clark, R. E.; Cohen, G. M.; Varadarajan, S.

Turning Squalene into Cationic Lipid Allows a Delivery of siRNA in Cultured Cells

NUCLEIC ACID THERAPEUTICS

IF4.7

2015-06-01

OAAI

Bertrand, Jean-Remi; Lucas, Claire; Ngoc Minh Pham; Durieu, Catherine; Couvreur, Patrick; Malvy, Claude Paul; Desmaele, Didier

Second generation tyrosine kinase inhibitors prevent disease progression in high-risk (high CIP2A) chronic myeloid leukaemia patients

LEUKEMIA

IF13.4

2015-03-13

PREAI

Lucas, C. M.; Harris, R. J.; Holcroft, A. K.; Scott, L. J.; Carmell, N.; McDonald, E.; Polydoros, F.; Clark, R. E.

AKT PHOSPHORYLATION AT SERINE 473 IS A POWERFUL NOVEL BIOMARKER IN ACUTE MYELOID LEUKAEMIA, AND IS RELATED TO PROTEIN PHOSPHATASE 2A (PP2A) INHIBITION BY CIP2A AND SETBP1

HAEMATOLOGICA

IF7.9

2015-02-06

OAAI

Lucas, C.; Carmell, N.; Scott, L.; Holcroft, A.; Hills, R.; Clark, R.

Low leukotriene B4 receptor 1 leads to ALOX5 downregulation at diagnosis of chronic myeloid leukemia

HAEMATOLOGICA

IF7.9

2014-09-05

OAAI

Lucas, Claire M.; Harris, Robert J.; Giannoudis, Athina; McDonald, Elizabeth; Clark, Richard E.

The clinical significance of ABCC3 as an imatinib transporter in chronic myeloid leukaemia

LEUKEMIA

IF13.4

2014-01-20

PREAI

Giannoudis, A.; Davies, A.; Harris, R. J.; Lucas, C. M.; Pirmohamed, M.; Clark, R. E.

Nilotinib concentration in cell lines and primary CD34+ chronic myeloid leukemia cells is not mediated by active uptake or efflux by major drug transporters 尼洛替尼在细胞系和原代CD34慢性粒细胞白血病细胞中的浓度不是由主要药物转运蛋白的主动摄取或流出介导的

LEUKEMIA

IF13.4

2009-08-27

PREAI

Davies, A.; Jordanides, N. E.; Giannoudis, A.; Lucas, C. M.; Hatziieremia, S.; Harris, R. J.; Jorgensen, H. G.; Holyoake, T. L.; Pirmohamed, M.; Clark, R. E.; Mountford, J. C.

A population study of imatinib in chronic myeloid leukaemia demonstrates lower efficacy than in clinical trials

LEUKEMIA

IF13.4

2008-08-28

PREAI

Lucas, C. M.; Wang, L.; Austin, G. M.; Knight, K.; Watmough, S. J.; Shwe, K. H.; Dasgupta, R.; Butt, Nauman M.; Galvani, D.; Hoyle, C. F.; Seale, J. R. C.; Clark, R. E.

Chemokine receptors expression and migration potential of tumor-infiltrating and peripheral-expanded Vγ9Vδ2 T cells from renal cell carcinoma patients

JOURNAL OF IMMUNOTHERAPY

IF2.9

2008-04-01

PREAI

Viey, Emilie; Lucas, Claire; Romagne, Francois; Escudier, Bernard; Chouaib, Salem; Caignard, Anne

研究方向