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E

Elizabeth Appleton

The Institute of Cancer Research
H指数:7
被引数:636

个人简介

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教育背景

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工作经历

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荣誉奖项

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Preclinical efficacy of a systemically-administered, second-generation STING agonist that promotes anti-tumour immunity in combination with radiotherapy

系统给药的第二代STING激动剂与放疗联合促进抗肿瘤免疫的预临床疗效

British Journal of Cancer
IF6.8
2026-10-150
OAAI
Malin Pedersen; Lisa C. Hubbard; Shane Foo; Anton Patrikeev; Antonio Rullan; Holly Baldock; Christian Mandl; Paolo Chetta; Jehanne Hassan; Isaac Dean; Naomi Guppy; Philippe Slos; Charleen Chan Wah Hak; Elizabeth Appleton; Emmanuel C. Patin; Rachel Hunt; Justin Weir; Masahiro Ono; Thorsten Oost; Ulrich Reiser; Thomas Zichner; Kevin Morse; Mary Murphy; Lingqi Luo; Reniqua House; Louise Giffin; Alan A. Melcher; Anne Vogt; Sebastian Carotta; Kevin J. Harrington
Xevinapant plus Chemoradiotherapy Negatively Sculpts the Tumor-Immune Microenvironment in Head and Neck Cancer

Xevinapant联合放化疗对头颈癌肿瘤免疫微环境的负面影响

Cancer Research Communications
IF0
2025-11-010
OA
Chan Wah Hak, Charleen; Patin, Emmanuel C.; Patrikeev, Anton; Nicastri, Annalisa; Kozik, Zuza; Baldock, Holly; Kyula-Currie, Joan N.; Roulstone, Victoria; Wongariyapak, Amarin; Gifford, Valentina; Tenev, Tencho; Appleton, Elizabeth S.; Hubbard, Lisa C.; Foo, Shane; Pedersen, Malin; Choudhary, Jyoti S.; Ono, Masahiro; Melcher, Alan A.; Rullan, Antonio; Harrington, Kevin J.
Author Correction: Palbociclib and dsRNA sensor co-operate to enhance anti-cancer effects through ER stress and modulation of immune evasion

作者更正: Palbociclib和dsRNA传感器合作通过ER应激和调节免疫逃避来增强抗癌作用

Nature Communications
IF15.7
2025-07-150
OAAI
Victoria Roulstone; Joan Kyula-Currie; James Wright; Emmanuel C. Patin; Isaac Dean; Lu Yu; Aida Barreiro-Alonso; Miriam Melake; Jyoti Choudhary; Richard Elliott; Christopher J. Lord; David Mansfield; Nik Matthews; Ritika Chauhan; Victoria Jennings; Charleen Chan Wah Hak; Holly Baldock; Francesca Butera; Elizabeth Appleton; Pablo Nenclares; Malin Pedersen; Shane Foo; Amarin Wongariyapak; Antonio Rullan; Tencho Tenev; Pascal Meier; Richard Vile; Hardev Pandha; Alan Melcher; Martin McLaughlin; Kevin J. Harrington
The PARP inhibitor talazoparib synergizes with reovirus to induce cancer killing and tumour control in vivo in mouse models

PARP抑制剂talazoparib与呼肠孤病毒协同作用，在小鼠模型中体内诱导癌症杀伤和肿瘤控制

Nature Communications
IF15.7
2025-07-080
OAAI
Joan Kyula-Currie; Victoria Roulstone; James Wright; Francesca Butera; Arnaud Legrand; Richard Elliott; Martin McLaughlin; Galabina Bozhanova; Dragomir Krastev; Stephen Pettitt; Tencho Tenev; Magnus Dillon; Shane Foo; Emmanuel C. Patin; Victoria Jennings; Charleen Chan Wah Hak; Elizabeth Appleton; Amarin Wongariyapak; Malin Pedersen; Antonio Rullan; Jyoti Choudhary; Chris Bakal; Pascal Meier; Christopher J. Lord; Alan Melcher; Kevin J. Harrington
Palbociclib and dsRNA sensor co-operate to enhance anti-cancer effects through ER stress and modulation of immune evasion
Nature Communications
IF15.7
2025-05-250
OAAI
Victoria Roulstone; Joan Kyula-Currie; James Wright; Emmanuel C. Patin; Isaac Dean; Lu Yu; Aida Barreiro-Alonso; Miriam Melake; Jyoti Choudhary; Richard Elliott; Christopher J. Lord; David Mansfield; Nik Matthews; Ritika Chauhan; Victoria Jennings; Charleen Chan Wah Hak; Holly Baldock; Francesca Butera; Elizabeth Appleton; Pablo Nenclares; Malin Pedersen; Shane Foo; Amarin Wongariyapak; Antonio Rullan; Tencho Tenev; Pascal Meier; Richard Vile; Hardev Pandha; Alan Melcher; Martin McLaughlin; Kevin J. Harrington
Intravenous delivery of oncolytic reovirus to brain tumor patients immunologically primes for subsequent checkpoint blockade
SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2018-01-03302
OAAI
Samson, Adel; Scott, Karen J.; Taggart, David; West, Emma J.; Wilson, Erica; Nuovo, Gerard J.; Thomson, Simon; Corns, Robert; Mathew, Ryan K.; Fuller, Martin J.; Kottke, Timothy J.; Thompson, Jill M.; Ilett, Elizabeth J.; Cockle, Julia V.; van Hille, Philip; Sivakumar, Gnanamurthy; Polson, Euan S.; Turnbull, Samantha J.; Appleton, Elizabeth S.; Migneco, Gemma; Rose, Ailsa S.; Coffey, Matthew C.; Beirne, Deborah A.; Collinson, Fiona J.; Ralph, Christy; Anthoney, D. Alan; Twelves, Christopher J.; Furness, Andrew J.; Quezada, Sergio A.; Wurdak, Heiko; Errington-Mais, Fiona; Pandha, Hardev; Harrington, Kevin J.; Selby, Peter J.; Vile, Richard G.; Griffin, Stephen D.; Stead, Lucy F.; Short, Susan C.; Melcher, Alan A.

研究方向

暂未获取到该数据
A
Alan Melcher
H 指数:71论文数:552被引数:1.6万
K
Kevin J. Harrington
H 指数:115论文数:1,484被引数:7.3万
C
Charleen Chan Wah Hak
H 指数:9论文数:40被引数:504
E
Emmanuel C. Patin
H 指数:19论文数:79被引数:2,219
R
Richard G. Vile
H 指数:77论文数:524被引数:1.8万
S
Shane Foo
H 指数:12论文数:63被引数:1,446
A
Antonio Rullan
H 指数:16论文数:120被引数:1,530
M
Masahiro Ono
H 指数:42论文数:343被引数:1.5万
V
Victoria Roulstone
H 指数:23论文数:105被引数:1,959
J
Jyoti S. Choudhary
H 指数:69论文数:458被引数:2.6万