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C

Christopher E. Dempsey

University of Bristol

H指数:43

被引数:6,558

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Quantitative analysis of trafficking defects induced by heterozygous expression of hERG voltage sensor domain variants

杂合表达hERG电压传感器结构域变异体诱导的囊泡运输缺陷的定量分析

IF3.2

2026-05-150

OAAI

Stereoselective block of the hERG potassium channel by the Class Ia antiarrhythmic drug disopyramide

CELLULAR AND MOLECULAR LIFE SCIENCES

IF6.2

2024-11-280

OAAI

Inhibition of the hERG Potassium Channel by a Methanesulphonate-Free E-4031 Analogue

PHARMACEUTICALS

IF4.8

2023-08-245

OAAI

Pro-arrhythmic effects of gain-of-function potassium channel mutations in the short QT syndrome

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

IF4.7

2023-05-0111

OAAI

Inhibition of the hERG potassium channel by phenanthrene: a polycyclic aromatic hydrocarbon pollutant

CELLULAR AND MOLECULAR LIFE SCIENCES

IF6.2

2021-11-0217

OAAI

Identification of a proton sensor that regulates conductance and open time of single hERG channels

SCIENTIFIC REPORTS

IF3.9

2019-12-2710

OAAI

Potent hERG channel inhibition by sarizotan, an investigative treatment for Rett Syndrome

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

IF4.7

2019-10-0112

OAAI

Functional and pharmacological characterization of an S5 domain hERG mutation associated with short QT syndrome

IF3.6

2019-04-019

OAAI

Analysis of α-Dystroglycan/LG Domain Binding Modes: Investigating Protein Motifs That Regulate the Affinity of Isolated LG Domains

FRONTIERS IN MOLECULAR BIOSCIENCES

IF4

2019-03-2920

OAAI

Structural implications of hERG K+ channel block by a high-affinity minimally structured blocker

高亲和力最小结构阻滞剂对hERG K通道阻滞的结构意义

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2018-05-0139

OAAI

Reprogramming the Activatable Peptide Display Function of Adeno-Associated Virus Nanoparticles

IF16

2017-12-2611

PREAI

The antimicrobial effects of the alginate oligomer OligoG CF-5/20 are independent of direct bacterial cell membrane disruption

SCIENTIFIC REPORTS

IF3.9

2017-03-3120

OAAI

The Roles of Selected Pore Residues in Pharmacological Inhibition of the hERG Potassium Channel by a Minimally Structured Blocker

BIOPHYSICAL JOURNAL

IF3.1

2017-02-010

OAAI

Interactions between amiodarone and the hERG potassium channel pore determined with mutagenesis and in silico docking

BIOCHEMICAL PHARMACOLOGY

IF5.6

2016-08-0140

OAAI

Arginine side chain interactions and the role of arginine as a gating charge carrier in voltage sensitive ion channels

SCIENTIFIC REPORTS

IF3.9

2016-02-22137

OAAI

hERG potassium channel inhibition by ivabradine requires channel gating

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

IF4.7

2015-10-012

PREAI

Molecular basis of hERG potassium channel blockade by the class Ic antiarrhythmic flecainide

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

IF4.7

2015-09-0151

OAAI

hERG Potassium Channel Blockade by the HCN Channel Inhibitor Bradycardic Agent Ivabradine

JOURNAL OF THE AMERICAN HEART ASSOCIATION

IF5.3

2015-04-2276

OAAI

Voltage Sensor Gating Charge Transfer in a hERG Potassium Channel Model

BIOPHYSICAL JOURNAL

IF3.1

2014-11-013

OAAI

Ranolazine inhibition of hERG potassium channels: Drug-pore interactions and reduced potency against inactivation mutants

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

IF4.7

2014-09-0144

OAAI