John P. Dalton - Publications, H-index & Citations

John P. Dalton

university of galway

73H指数

382论文数

1.5W被引数

收录论文 104

发表时间

Dynamic shifts in isomiR profiles during parasite maturation of Fasciola hepatica Fasciola hepatica寄生虫成熟过程中异型miRNA谱的动态变化

RNA Biology

IF3.4

2025-07-31

OAAI

Dayna Sais; Sumaiya Chowdhury; Phuong Thao Nguyen; Krystyna Cwiklinski; Trung Duc Nguyen; Tuan Anh Nguyen; John Dalton; Sheila Donnelly; Nham Tran

In vitro co-culture of Fasciola hepatica newly excysted juveniles (NEJs) with 3D HepG2 spheroids permits novel investigation of host-parasite interactions 在体外将肝片吸虫新脱囊幼体（NEJs）与三维HepG2细胞球体共培养，能够实现对宿主-寄生虫相互作用的全新研究

VIRULENCE

IF5.4

2025-03-25

OAAI

Aiste Vitkauskaite; Emma McDermott; Richard Lalor; Carolina De Marco Verissimo; Mahshid H. Dehkordi; Kerry Thompson; Peter Owens; Howard Oliver Fearnhead; John Pius Dalton; Nichola Eliza Davies Calvani

An immunoregulatory amphipathic peptide derived from Fasciola hepatica helminth defense molecule (FhHDM-1.C2) exhibits potent biotherapeutic activity in a murine model of multiple sclerosis

FASEB JOURNAL

IF4.2

2025-02-14

OAAI

Lalor, Richard; Tanaka, Akane; Shiels, Jenna; Dixit, Aakanksha; Hoadley, Sabine; Dufourd, Eloise; Hamon, Siobhan; To, Joyce; Taggart, Clifford C.; Weldon, Sinead; O'Brien, Bronwyn; Greer, Judith; Dalton, John P.; Donnelly, Sheila

Both host and parasite non-coding RNAs co-ordinate the regulation of macrophage gene expression to reduce pro-inflammatory immune responses and promote tissue repair pathways during infection with fasciola hepatica 宿主和寄生虫非编码rna均协调巨噬细胞基因表达的调节，以减少促炎免疫反应并促进肝片吸虫感染期间的组织修复途径

RNA BIOLOGY

IF3.4

2024-09-30

OAAI

Sais, Dayna; Chowdhury, Sumaiya; Dalton, John. P.; Tran, Nham; Donnelly, Sheila

Moonlighting on the Fasciola hepatica tegument: Enolase, a glycolytic enzyme, interacts with the extracellular matrix and fibrinolytic system of the host

PLOS NEGLECTED TROPICAL DISEASES

IF3.4

2024-08-30

OAAI

O'Kelly, Eve; Cwiklinski, Krystyna; Verissimo, Carolina De Marco; Calvani, Nichola Eliza Davies; Corrales, Jesus Lopez; Jewhurst, Heather; Flaus, Andrew; Lalor, Richard; Serrat, Judit; Dalton, John P.; Gonzalez-Miguel, Javier

Exploring the utility of circulating miRNAs as diagnostic biomarkers of fasciolosis

SCIENTIFIC REPORTS

IF3.9

2024-03-28

OAAI

Chowdhury, Sumaiya; Ricafrente, Alison; Cwiklinski, Krystyna; Sais, Dayna; Dalton, John P.; Tran, Nham; Donnelly, Sheila

Glycan Complexity and Heterogeneity of Glycoproteins in Somatic Extracts and Secretome of the Infective Stage of the Helminth Fasciola hepatica

MOLECULAR & CELLULAR PROTEOMICS

IF5.5

2023-12-01

OAAI

Verissimo, Carolina De Marco; Cwiklinski, Krystyna; Nilsson, Jonas; Mirgorodskaya, Ekaterina; Jin, Chunsheng; Karlsson, Niclas G.; Dalton, John P.

In vitro evaluation of the potential use of snake-derived peptides in the treatment of respiratory infections using inhalation therapy: A proof of concept study

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

IF4.7

2023-04-01

OAAI

Creane, Shannice; Joyce, Mary; MacLoughlin, Ronan; Weldon, Sinead; Dalton, John P.; Taggart, Clifford C.

Omics tools enabling vaccine discovery against fasciolosis

Trends in Parasitology

IF6.6

2022-12-01

OAAI

Cwiklinski, Krystyna; Dalton, John P.

Two Distinct Superoxidase Dismutases (SOD) Secreted by the Helminth Parasite Fasciola hepatica Play Roles in Defence against Metabolic and Host Immune Cell-Derived Reactive Oxygen Species (ROS) during Growth and Development

ANTIOXIDANTS

IF6.6

2022-09-30

OAAI

Calvani, Nichola Eliza Davies; Verissimo, Carolina De Marco; Jewhurst, Heather Louise; Cwiklinski, Krystyna; Flaus, Andrew; Dalton, John Pius

Stage-specific miRNAs regulate gene expression associated with growth, development and parasite-host interaction during the intra-mammalian migration of the zoonotic helminth parasite Fasciola hepatica

BMC GENOMICS

IF3.7

2022-06-04

OAAI

Ricafrente, Alison; Cwiklinski, Krystyna; Nguyen, Hieu; Dalton, John P.; Tran, Nham; Donnelly, Sheila

Tuaimenal A, a Meroterpene from the Irish Deep-Sea Soft Coral Duva florida, Displays Inhibition of the SARS-CoV-2 3CLpro Enzyme

JOURNAL OF NATURAL PRODUCTS

IF3.6

2022-05-12

OAAI

Avalon, Nicole E.; Nafie, Jordan; Verissimo, Carolina De Marco; Warrensford, Luke C.; Dietrick, Sarah G.; Pittman, Amanda R.; Young, Ryan M.; Kearns, Fiona L.; Smalley, Tracess; Binning, Jennifer M.; Dalton, John P.; Johnson, Mark P.; Woodcock, H. Lee; Allcock, A. Louise; Baker, Bill J.

Targeting Secreted Protease/Anti-Protease Balance as a Vaccine Strategy against the Helminth Fasciola hepatica

VACCINES

IF3.4

2022-01-20

OAAI

Cwiklinski, Krystyna; Drysdale, Orla; Lopez Corrales, Jesus; Corripio-Miyar, Yolanda; De Marco Verissimo, Carolina; Jewhurst, Heather; Smith, David; Lalor, Richard; McNeilly, Tom N.; Dalton, John P.

Fasciola hepatica is refractory to complement killing by preventing attachment of mannose binding lectin (MBL) and inhibiting MBL-associated serine proteases (MASPs) with serpins

PLOS PATHOGENS

IF4.9

2022-01-10

OAAI

De Marco Verissimo, Carolina; Jewhurst, Heather L.; Dobo, Jozsef; Gal, Peter; Dalton, John P.; Cwiklinski, Krystyna

The anti-inflammatory effects of helminth-derived peptides in a model of endotoxin-induced acute lung injury

EUROPEAN RESPIRATORY JOURNAL

IF21

2021-11-25

PREAI

Ryan, Sinead; Shiels, Jenna; Taggart, Clifford C.; Dalton, John P.; Weldon, Sinead

Pathogenicity and virulence of the liver flukes Fasciola hepatica and Fasciola Gigantica that cause the zoonosis Fasciolosis 引起人畜共患病的肝吸虫肝片吸虫和巨大性吸虫的致病性和毒力

VIRULENCE

IF5.4

2021-11-22

OAAI

Lalor, Richard; Cwiklinski, Krystyna; Calvani, Nichola Eliza Davies; Dorey, Amber; Hamon, Siobhan; Corrales, Jesus Lopez; Dalton, John Pius; Verissimo, Carolina De Marco

Antigen-specific response of CD4+ T cells and hepatic lymph node cells to Fasciola hepatica-derived molecules at the early and late stage of the infection in sheep

VETERINARY RESEARCH

IF3.5

2021-07-02

OAAI

Perez-Caballero, Raul; Martinez-Moreno, F. Javier; Corripio-Miyar, Yolanda; McNeilly, Tom N.; Cwiklinski, Krystyna; Dalton, John P.; Zafra, Rafael; Perez, Jose; Martinez-Moreno, Alvaro; Buffoni, Leandro

Recognition Pattern of the Fasciola hepatica Excretome/Secretome during the Course of an Experimental Infection in Sheep by 2D Immunoproteomics

PATHOGENS

IF3.3

2021-06-09

OAAI

Becerro-Recio, David; Gonzalez-Miguel, Javier; Ucero, Alberto; Sotillo, Javier; Martinez-Moreno, Alvaro; Perez-Arevalo, Jose; Cwiklinski, Krystyna; Dalton, John P.; Siles-Lucas, Mar

Eudiplozoon nipponicum (Monogenea, Diplozoidae) and its adaptation to haematophagy as revealed by transcriptome and secretome profiling

BMC GENOMICS

IF3.7

2021-04-15

OAAI

Vorel, Jiri; Cwiklinski, Krystyna; Roudnicky, Pavel; Ilgova, Jana; Jedlickova, Lucie; Dalton, John P.; Mikes, Libor; Gelnar, Milan; Kasny, Martin

Fasciola hepatica hijacks host macrophage miRNA machinery to modulate early innate immune responses

SCIENTIFIC REPORTS

IF3.9

2021-03-24

OAAI

Tran, Nham; Ricafrente, Alison; To, Joyce; Lund, Maria; Marques, Tania M.; Gama-Carvalho, Margarida; Cwiklinski, Krystyna; Dalton, John P.; Donnelly, Sheila

研究方向