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E

Ella N. Hoogenboezem

Vanderbilt University
H指数:9
被引数:823

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Intravenous lipid-siRNA conjugate mediates gene silencing at the blood-brain barrier and blood-CSF barrier

静脉注射脂质-siRNA缀合物在血脑屏障和血-脑脊液屏障介导基因沉默

Journal of Controlled Release
IF11.5
2025-09-110
OA
Alexander G. Sorets; Katrina R. Schwensen; Nora Francini; Andrew Kjar; Sarah Lyons; Joshua C. Park; Dillon Palmer; Adam M. Abdulrahman; Rebecca P. Cowell; Ketaki A. Katdare; Ella N. Hoogenboezem; Angela Wang; Alexander P. Ligocki; Rebecca J. Embalabala; Neil Dani; Craig L. Duvall; Ethan S. Lippmann
Elucidating brain transport pathways and cell type-dependent gene silencing of a durable lipid-siRNA conjugate administered into cerebrospinal fluid

阐明一种耐用的脂质-siRNA缀合物经脑脊液给药后的脑内转运途径及细胞类型依赖性基因沉默

NUCLEIC ACIDS RESEARCH
IF13.1
2025-07-082
OAAI
Sorets, Alexander G.; Schwensen, Katrina R.; Francini, Nora; Kjar, Andrew; Abdulrahman, Adam M.; Shostak, Alena; Katdare, Ketaki A.; Schoch, Kathleen M.; Cowell, Rebecca P.; Park, Joshua C.; Ligocki, Alexander P.; Ford, William T.; Ventura-Antunes, Lissa; Hoogenboezem, Ella N.; Prusky, Alex; Castleberry, Mark; Michell, Danielle L.; Fritsch, Emma; Lyons, Sarah M.; Miller, Timothy M.; Vickers, Kasey C.; Schrag, Matthew S.; Duvall, Craig L.; Lippmann, Ethan S.
siRNA conjugate with high albumin affinity and degradation resistance for delivery and treatment of arthritis in mice and guinea pigs

具有高白蛋白亲和力和降解抵抗性的siRNA缀合物，用于小鼠和大鼠的关节炎递送与治疗

NATURE BIOMEDICAL ENGINEERING
IF26.6
2025-05-160
OA
Colazo, Juan M.; Keech, Megan C.; Shah, Veeraj; Hoogenboezem, Ella N.; Lo, Justin H.; Francini, Nora; Cassidy, Nina T.; Yu, Fang; Sorets, Alexander G.; Mccune, Joshua T.; Dejulius, Carlisle R.; Cho, Hongsik; Michell, Danielle L.; Vickers, Kacey C.; Gibson-Corley, Katherine N.; Hasty, Karen A.; Crofford, Leslie J.; Cook, Rebecca S.; Duvall, Craig L.
Structural optimization of siRNA conjugates for albumin binding achieves effective MCL1-directed cancer therapy
NATURE COMMUNICATIONS
IF15.7
2024-02-212
OAAI
Hoogenboezem, Ella N.; Patel, Shrusti S.; Lo, Justin H.; Cavnar, Ashley B.; Babb, Lauren M.; Francini, Nora; Gbur, Eva F.; Patil, Prarthana; Colazo, Juan M.; Michell, Danielle L.; Sanchez, Violeta M.; Mccune, Joshua T.; Ma, Jinqi; Dejulius, Carlisle R.; Lee, Linus H.; Rosch, Jonah C.; Allen, Ryan M.; Stokes, Larry D.; Hill, Jordan L.; Vickers, Kasey C.; Cook, Rebecca S.; Duvall, Craig L.

研究方向

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C
Craig L. Duvall
H 指数:50论文数:267被引数:8,772
N
Nora Francini
H 指数:15论文数:83被引数:635
A
Alexander G. Sorets
H 指数:8论文数:23被引数:434
S
Shrusti S. Patel
H 指数:6论文数:62被引数:200
J
Justin H. Lo
H 指数:15论文数:104被引数:1,482
F
Fang Yu
H 指数:21论文数:91被引数:1,874
C
Carlisle R. DeJulius
H 指数:11论文数:21被引数:576
D
Danielle L. Michell
H 指数:17论文数:70被引数:1,085
R
Rebecca S. Cook
H 指数:45论文数:255被引数:8,009
E
Ethan S. Lippmann
H 指数:26论文数:126被引数:4,311