未登录 Amniotic fluid-derived stem cells: potential factories of natural and mimetic strategies for congenital malformations Fonteles, Cristiane S. R.; Enterria-Rosales, Julia; Lin, Ying; Steele, John W.; Villarreal-Leal, Ramiro A.; Xiao, Jing; Idowu, Daniel I.; Burgelin, Beck; Wlodarczyk, Bogdan J.; Finnell, Richard H.; Corradetti, Bruna 分享 收藏
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Optical coherence tomography-guided Brillouin microscopy highlights regional tissue stiffness differences during anterior neural tube closure in the Mthfd1l murine mutant Ambekar, Yogeshwari S.; Caiaffa, Carlo Donato; Wlodarczyk, Bogdan J.; Singh, Manmohan; Schill, Alexander W.; Steele, John W.; Zhang, Jitao; Aglyamov, Salavat R.; Scarcelli, Giuliano; Finnell, Richard H.; Larin, Kirill, V 分享 收藏
Excess folic acid intake increases DNA de novo point mutations Cao, Xuanye; Xu, Jianfeng; Lin, Ying L.; Cabrera, Robert M.; Chen, Qiuying; Zhang, Chaofan; Steele, John W.; Han, Xiao; Gross, Steven S.; Wlodarczyk, Bogdan J.; Lupski, James R.; Li, Wei; Wang, Hongyan; Finnell, Richard H.; Lei, Yunping 分享 收藏
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FKBP8 variants are risk factors for spina bifida Tian, Tian; Cao, Xuanye; Kim, Sung-Eun; Lin, Ying Linda; Steele, John W.; Cabrera, Robert M.; Karki, Menuka; Yang, Wei; Marini, Nicholas J.; Hoffman, Ethan N.; Han, Xiao; Hu, Cindy; Wang, Linlin; Wlodarczyk, Bogdan J.; Shaw, Gary M.; Ren, Aiguo; Finnell, Richard H.; Lei, Yunping 分享 收藏
CIC de novo loss of function variants contribute to cerebral folate deficiency by downregulating FOLR1 expression Cao, Xuanye; Wolf, Annika; Kim, Sung-Eun; Cabrera, Robert M.; Wlodarczyk, Bogdan J.; Zhu, Huiping; Parker, Margaret; Lin, Ying; Steele, John W.; Han, Xiao; Ramaekers, Vincent Th; Steinfeld, Robert; Finnell, Richard H.; Lei, Yunping 分享 收藏
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The epichaperome is a mediator of toxic hippocampal stress and leads to protein connectivity-based dysfunction Inda, Maria Carmen; Joshi, Suhasini; Wang, Tai; Bolaender, Alexander; Gandu, Srinivasa; Koren, John, III; Che, Alicia Yue; Taldone, Tony; Yan, Pengrong; Sun, Weilin; Uddin, Mohammad; Panchal, Palak; Riolo, Matthew; Shah, Smit; Barlas, Afsar; Xu, Ke; Chan, Lon Yin L.; Gruzinova, Alexandra; Kishinevsky, Sarah; Studer, Lorenz; Fossati, Valentina; Noggle, Scott A.; White, Julie R.; de Stanchina, Elisa; Sequeira, Sonia; Anthoney, Kyle H.; Steele, John W.; Manova-Todorova, Katia; Patil, Sujata; Dunphy, Mark P.; Pillarsetty, NagaVaraKishore; Pereira, Ana C.; Erdjument-Bromage, Hediye; Neubert, Thomas A.; Rodina, Anna; Ginsberg, Stephen D.; Garcia, Natalia De Marco; Luo, Wenjie; Chiosis, Gabriela 分享 收藏
Loss of RAD9B impairs early neural development and contributes to the risk for human spina bifida Cao, Xuanye; Tian, Tian; Steele, John W.; Cabrera, Robert M.; Aguiar-Pulido, Vanessa; Wadhwa, Shruti; Bhavani, Nikitha; Bi, Patrick; Gargurevich, Nick H.; Hoffman, Ethan N.; Cai, Chun-Quan; Marini, Nicholas J.; Yang, Wei; Shaw, Gary M.; Ross, Margaret E.; Finnell, Richard H.; Lei, Yunping 分享 收藏
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Selective Nonsteroidal Glucocorticoid Receptor Modulators for the Inhaled Treatment of Pulmonary Diseases Hemmerling, Martin; Nilsson, Stinabritt; Edman, Karl; Eirefelt, Stefan; Russell, Wayne; Hendrickx, Ramon; Johnsson, Eskil; Mardh, Carina Karrman; Berger, Markus; Rehwinkel, Hartmut; Abrahamsson, Anna; Dahmen, Jan; Eriksson, Anders R.; Gabos, Balint; Henriksson, Krister; Hossain, Nafizal; Ivanova, Svetlana; Jansson, Anne-Helene; Jensen, Tina J.; Jerre, Anders; Johansson, Henrik; Klingstedt, Tomas; Lepisto, Matti; Lindsjo, Martin; Mile, Irene; Nikitidis, Grigorios; Steele, John; Tehler, Ulrika; Wissler, Lisa; Hanson, Thomas 分享 收藏
Discovery of AZD-2098 and AZD-1678, Two Potent and Bioavailable CCR4 Receptor Antagonists Kindon, Nicholas; Andrews, Glen; Baxter, Andrew; Cheshire, David; Hemsley, Paul; Johnson, Timothy; Liu, Yu-Zhen; McGinnity, Dermot; McHale, Mark; Mete, Antonio; Reuberson, James; Roberts, Bryan; Steele, John; Teobald, Barry; Unitt, John; Vaughan, Deborah; Walters, Iain; Stocks, Michael J. 分享 收藏
Effective anti-Alzheimer Aβ therapy involves depletion of specific Aβ oligomer subtypes Knight, Elysse M.; Kim, Soong Ho; Kottwitz, Jessica C.; Hatami, Asa; Albay, Ricardo; Suzuki, Akinobu; Lublin, Alex; Alberini, Cristina M.; Klein, William L.; Szabo, Paul; Relkin, Norman R.; Ehrlich, Michelle; Glabe, Charles G.; Gandy, Sam; Steele, John W. 分享 收藏
Physiologically generated presenilin 1 lacking exon 8 fails to rescue brain PS1-/- phenotype and forms complexes with wildtype PS1 and nicastrin Brautigam, Hannah; Moreno, Cesar L.; Steele, John W.; Bogush, Alexey; Dickstein, Dara L.; Kwok, John B. J.; Schofield, Peter R.; Thinakaran, Gopal; Mathews, Paul M.; Hof, Patrick R.; Gandy, Sam; Ehrlich, Michelle E. 分享 收藏
Evidence that small molecule enhancement of β-hexosaminidase activity corrects the behavioral phenotype in Dutch APPE693Q mice through reduction of ganglioside-bound Aβ Knight, E. M.; Williams, H. N.; Stevens, A. C.; Kim, S. H.; Kottwitz, J. C.; Morant, A. D.; Steele, J. W.; Klein, W. L.; Yanagisawa, K.; Boyd, R. E.; Lockhart, D. J.; Sjoberg, E. R.; Ehrlich, M. E.; Wustman, B. A.; Gandy, S. 分享 收藏
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Proneurogenic Group II mGluR antagonist improves learning and reduces anxiety in Alzheimer Aβ oligomer mouse Kim, S. H.; Steele, J. W.; Lee, S. W.; Clemenson, G. D.; Carter, T. A.; Treuner, K.; Gadient, R.; Wedel, P.; Glabe, C.; Barlow, C.; Ehrlich, M. E.; Gage, F. H.; Gandy, S. 分享 收藏
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