Hilary K. Finucane - Publications, H-index & Citations

Hilary K. Finucane

massachusetts general hospital

75H指数

201论文数

5.3W被引数

收录论文 51

发表时间

An encyclopedia of human enhancer–gene regulatory interactions 人类增强子-基因调控互作百科全书

Nature

IF48.5

2026-07-15

OAAI

Andreas R. Gschwind; Kristy S. Mualim; Alireza Karbalayghareh; Maya U. Sheth; Kushal K. Dey; Evelyn Jagoda; Ramil N. Nurtdinov; Wang Xi; Anthony S. Tan; James Galante; Hank Jones; X. Rosa Ma; David Yao; Dulguun Amgalan; Judhajeet Ray; Chad J. Munger; Joseph Nasser; Žiga Avsec; Benjamin T. James; Muhammad S. Shamim; Neva C. Durand; Suhas S. P. Rao; Ragini Mahajan; Benjamin R. Doughty; Kalina Andreeva; Jacob C. Ulirsch; Kaili Fan; Elizabeth M. Perez; Tri C. Nguyen; David R. Kelley; Hilary K. Finucane; Jill E. Moore; Zhiping Weng; Manolis Kellis; Michael C. Bassik; Berk Ustun; Alkes L. Price; Michael A. Beer; Roderic Guigó; John A. Stamatoyannopoulos; Erez Lieberman Aiden; William J. Greenleaf; Christina S. Leslie; Lars M. Steinmetz; Anshul Kundaje; Jesse M. Engreitz

Functional dissection of complex trait variants at single-nucleotide resolution 在单核苷酸分辨率下对复杂性状变异的功能解析

Nature

IF48.5

2026-02-25

OAAI

Layla Siraj; Rodrigo I. Castro; Hannah B. Dewey; Susan Kales; John C. Butts; Thanh Thanh L. Nguyen; Masahiro Kanai; Daniel Berenzy; Kousuke Mouri; Qingbo S. Wang; Petko P. Fiziev; Kristin Tsuo; Zachary R. McCaw; Sager J. Gosai; François Aguet; Ran Cui; Irfahan Kassam; Jeremy McRae; Christopher M. Vockley; Caleb A. Lareau; Sergey Abramov; Alexandr Boystov; Jeff Vierstra; Yukinori Okada; Alexander Gusev; Thouis R. Jones; Eric S. Lander; Pardis C. Sabeti; Hilary K. Finucane; Steven K. Reilly; Jacob C. Ulirsch; Ryan Tewhey

Widespread naturally variable human exons aid genetic interpretation 广泛分布的自然变异人类外显子有助于遗传学解释

Nature Communications

IF15.7

2025-12-16

OAAI

Hannah N. Jacobs; Bram L. Gorissen; Jeremy Guez; Masahiro Kanai; Kavi Gupta; Hilary K. Finucane; Konrad J. Karczewski; Christopher B. Burge

Pan-UK Biobank genome-wide association analyses enhance discovery and resolution of ancestry-enriched effects 全英生物银行全基因组关联分析增强了祖先富集效应的发现和解析

Nature Genetics

IF0

2025-09-18

PREAI

Konrad J. Karczewski; Rahul Gupta; Masahiro Kanai; Wenhan Lu; Kristin Tsuo; Ying Wang; Raymond K. Walters; Patrick Turley; Shawneequa Callier; Nirav N. Shah; Nikolas Baya; Duncan S. Palmer; Jacqueline I. Goldstein; Gopal Sarma; Matthew Solomonson; Nathan Cheng; Sam Bryant; Claire Churchhouse; Caroline M. Cusick; Timothy Poterba; John Compitello; Daniel King; Wei Zhou; Cotton Seed; Hilary K. Finucane; Mark J. Daly; Benjamin M. Neale; Elizabeth G. Atkinson; Alicia R. Martin

Cell-type-specific Alzheimer's disease polygenic risk scores are associated with distinct disease processes in Alzheimer's disease

NATURE COMMUNICATIONS

IF15.7

2023-11-30

OAAI

Yang, Hyun-Sik; Teng, Ling; Kang, Daniel; Menon, Vilas; Ge, Tian; Finucane, Hilary K.; Schultz, Aaron P.; Properzi, Michael; Klein, Hans-Ulrich; Chibnik, Lori B.; Schneider, Julie A.; Bennett, David A.; Hohman, Timothy J.; Mayeux, Richard P.; Johnson, Keith A.; De Jager, Philip L.; Sperling, Reisa A.

Improving fine-mapping by modeling infinitesimal effects 通过对无穷小效应建模来改善精细映射

NATURE GENETICS

IF31.8

2023-11-30

OAAI

Cui, Ran; Elzur, Roy A.; Kanai, Masahiro; Ulirsch, Jacob C.; Weissbrod, Omer; Daly, Mark J.; Neale, Benjamin M.; Fan, Zhou; Finucane, Hilary K.

eQTL Catalogue 2023: New datasets, X chromosome QTLs, and improved detection and visualisation of transcript-level QTLs

PLOS GENETICS

IF3.7

2023-09-18

OAAI

Kerimov, Nurlan; Tambets, Ralf; Hayhurst, James D.; Rahu, Ida; Kolberg, Peep; Raudvere, Uku; Kuzmin, Ivan; Chowdhary, Anshika; Vija, Andreas; Teras, Hans J.; Kanai, Masahiro; Ulirsch, Jacob; Ryten, Mina; Hardy, John; Guelfi, Sebastian; Trabzuni, Daniah; Kim-Hellmuth, Sarah; Rayner, William; Finucane, Hilary; Peterson, Hedi; Mosaku, Abayomi; Parkinson, Helen; Alasoo, Kaur

Leveraging polygenic enrichments of gene features to predict genes underlying complex traits and diseases 利用基因特征的多基因富集来预测复杂性状和疾病背后的基因

NATURE GENETICS

IF31.8

2023-07-13

OAAI

Weeks, Elle M. M.; Ulirsch, Jacob C. C.; Cheng, Nathan Y. Y.; Trippe, Brian L. L.; Fine, Rebecca S. S.; Miao, Jenkai; Patwardhan, Tejal A. A.; Kanai, Masahiro; Nasser, Joseph; Fulco, Charles P. P.; Tashman, Katherine C. C.; Aguet, Francois; Li, Taibo; Ordovas-Montanes, Jose; Smillie, Christopher S. S.; Biton, Moshe; Shalek, Alex K. K.; Ananthakrishnan, Ashwin N. N.; Xavier, Ramnik J. J.; Regev, Aviv; Gupta, Rajat M. M.; Lage, Kasper; Ardlie, Kristin G. G.; Hirschhorn, Joel N. N.; Lander, Eric S. S.; Engreitz, Jesse M. M.; Finucane, Hilary K. K.

FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity FALCON系统地询问游离脂肪酸生物学并鉴定出一种新的脂毒性介质

CELL METABOLISM

IF30.9

2023-05-01

OAAI

Wieder, Nicolas; Fried, Juliana Coraor; Kim, Choah; Sidhom, Eriene-Heidi; Brown, Matthew R.; Marshall, Jamie L.; Arevalo, Carlos; Dvela-Levitt, Moran; Kost-Alimova, Maria; Sieber, Jonas; Gabriel, Katlyn R.; Pacheco, Julian; Clish, Clary; Abbasi, Hamdah Shafqat; Singh, Shantanu; Rutter, Justine C.; Therrien, Martine; Yoon, Haejin; Lai, Zon Weng; Baublis, Aaron; Subramanian, Renuka; Devkota, Ranjan; Small, Jonnell; Sreekanth, Vedagopuram; Han, Myeonghoon; Lim, Donghyun; Carpenter, Anne E.; Flannick, Jason; Finucane, Hilary; Haigis, Marcia C.; Claussnitzer, Melina; Sheu, Eric; Stevens, Beth; Wagner, Bridget K.; Choudhary, Amit; Shaw, Jillian L.; Pablo, Juan Lorenzo; Greka, Anna

Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants 超过一百万参与者的冠状动脉疾病风险变异和基因的发现和系统表征

NATURE GENETICS

IF31.8

2022-12-06

200

OAAI

Aragam, Krishna G.; Jiang, Tao; Goel, Anuj; Kanoni, Stavroula; Wolford, Brooke N.; Atri, Deepak S.; Weeks, Elle M.; Wang, Minxian; Hindy, George; Zhou, Wei; Grace, Christopher; Roselli, Carolina; Marston, Nicholas A.; Kamanu, Frederick K.; Surakka, Ida; Venegas, Loreto Munoz; Sherliker, Paul; Koyama, Satoshi; Ishigaki, Kazuyoshi; Asvold, Bjorn O.; Brown, Michael R.; Brumpton, Ben; de Vries, Paul S.; Giannakopoulou, Olga; Giardoglou, Panagiota; Gudbjartsson, Daniel F.; Gueldener, Ulrich; Haider, Syed M. Ijlal; Helgadottir, Anna; Ibrahim, Maysson; Kastrati, Adnan; Kessler, Thorsten; Kyriakou, Theodosios; Konopka, Tomasz; Li, Ling; Ma, Lijiang; Meitinger, Thomas; Mucha, Soeren; Munz, Matthias; Murgia, Federico; Nielsen, Jonas B.; Noethen, Markus M.; Pang, Shichao; Reinberger, Tobias; Schnitzler, Gavin; Smedley, Damian; Thorleifsson, Gudmar; von Scheidt, Moritz; Ulirsch, Jacob C.; Arnar, David O.; Burtt, Noel P.; Costanzo, Maria C.; Flannick, Jason; Ito, Kaoru; Jang, Dong-Keun; Kamatani, Yoichiro; Khera, Amit V.; Komuro, Issei; Kullo, Iftikhar J.; Lotta, Luca A.; Nelson, Christopher P.; Roberts, Robert; Thorgeirsson, Gudmundur; Thorsteinsdottir, Unnur; Webb, Thomas R.; Baras, Aris; Bjoerkegren, Johan L. M.; Boerwinkle, Eric; Dedoussis, George; Holm, Hilma; Hveem, Kristian; Melander, Olle; Morrison, Alanna C.; Orho-Melander, Marju; Rallidis, Loukianos S.; Ruusalepp, Arno; Sabatine, Marc S.; Stefansson, Kari; Zalloua, Pierre; Ellinor, Patrick T.; Farrall, Martin; Danesh, John; Ruff, Christian T.; Finucane, Hilary K.; Hopewell, Jemma C.; Clarke, Robert; Gupta, Rajat M.; Erdmann, Jeanette; Samani, Nilesh J.; Schunkert, Heribert; Watkins, Hugh; Willer, Cristen J.; Deloukas, Panos; Kathiresan, Sekar; Butterworth, Adam S.

Global Biobank Meta-analysis Initiative: Powering genetic discovery across human disease 全球生物银行荟萃分析倡议: 推动人类疾病的基因发现

CELL GENOMICS

IF9

2022-10-01

126

OAAI

Zhou, Wei; Kanai, Masahiro; Wu, Kuan-Han H.; Rasheed, Humaira; Tsuo, Kristin; Hirbo, Jibril B.; Wang, Ying; Bhattacharya, Arjun; Zhao, Huiling; Namba, Shinichi; Surakka, Ida; Wolford, Brooke N.; Lo Faro, Valeria; Lopera-Maya, Esteban A.; Lall, Kristi; Fave, Marie-Julie; Partanen, Juulia J.; Chapman, Sine ad B.; Karjalainen, Juha; Kurki, Mitja; Maasha, Mutaamba; Brumpton, Ben M.; Chavan, Sameer; Chen, Tzu-Ting; Daya, Michelle; Ding, Yi; Feng, Yen-Chen A.; Guare, Lindsay A.; Gignoux, Christopher R.; Graham, Sarah E.; Hornsby, Whitney E.; Ingold, Nathan; Ismail, Said I.; Johnson, Ruth; Laisk, Triin; Lin, Kuang; Lv, Jun; Millwood, Iona Y.; Moreno-Grau, Sonia; Nam, Kisung; Palta, Priit; Pandit, Anita; Preuss, Michael H.; Saad, Chadi; Setia-Verma, Shefali; Thorsteinsdottir, Unnur; Uzunovic, Jasmina; Verma, Anurag; Zawistowski, Matthew; Zhong, Xue; Afifi, Nahla; Al-Dabhani, Kawthar M.; Al Thani, Asma; Bradford, Yuki; Campbell, Archie; Crooks, Kristy; de Bock, Geertruida H.; Damrauer, Scott M.; Douville, Nicholas J.; Finer, Sarah; Fritsche, Lars G.; Fthenou, Eleni; Gonzalez-Arroyo, Gilberto; Griffiths, Christopher J.; Guo, Yu; Hunt, Karen A.; Ioannidis, Alexander; Jansonius, Nomdo M.; Konuma, Takahiro; Lee, Ming Ta Michael; Lopez-Pineda, Arturo; Matsuda, Yuta; Marioni, Riccardo E.; Moatamed, Babak; Nava-Aguilar, Marco A.; Numakura, Kensuke; Patil, Snehal; Rafaels, Nicholas; Richmond, Anne; Rojas-Munoz, Agustin; Shortt, Jonathan A.; Straub, Peter; Tao, Ran; Vanderwerff, Brett; Vernekar, Manvi; Veturi, Yogasudha; Barnes, Kathleen C.; Boezen, Marike; Chen, Zhengming; Chen, Chia-Yen; Cho, Judy; Smith, George Davey; Finucane, Hilary K.; Franke, Lude; Gamazon, Eric R.; Ganna, Andrea; Gaunt, Tom R.; Ge, Tian; Huang, Hailiang; Huffman, Jennifer; Katsanis, Nicholas; Koskela, Jukka T.; Lajonchere, Clara; Law, Matthew H.; Li, Liming; Lindgren, Cecilia M.; Loos, Ruth J. F.; MacGregor, Stuart; Matsuda, Koichi; Olsen, Catherine M.; Porteous, David J.; Shavit, Jordan A.; Snieder, Harold; Takano, Tomohiro; Trembath, Richard C.; Vonk, Judith M.; Whiteman, David C.; Wicks, Stephen J.; Wijmenga, Cisca; Wright, John; Zheng, Jie; Zhou, Xiang; Awadalla, Philip; Boehnke, Michael; Bustamante, Carlos D.; Cox, Nancy J.; Fatumo, Segun; Geschwind, Daniel H.; Hayward, Caroline; Hveem, Kristian; Kenny, Eimear E.; Lee, Seunggeun; Lin, Yen-Feng; Mbarek, Hamdi; Magi, Reedik; Martin, Hilary C.; Medland, Sarah E.; Okada, Yukinori; Palotie, Aarno, V; Pasaniuc, Bogdan; Rader, Daniel J.; Ritchie, Marylyn D.; Sanna, Serena; Smoller, Jordan W.; Stefansson, Kari; van Heel, David A.; Walters, Robin G.; Zollner, Sebastian; Martin, Alicia R.; Willer, Cristen J.; Daly, Mark J.; Neale, Benjamin M.

Genome-wide pleiotropy analysis of coronary artery disease and pneumonia identifies shared immune pathways

SCIENCE ADVANCES

IF12.5

2022-04-22

OAAI

Yu, Zhi; Zekavat, Seyedeh M.; Haidermota, Sara; Bernardo, Rachel; MacDonald, Bryan T.; Libby, Peter; Finucane, Hilary K.; Natarajan, Pradeep

Leveraging fine-mapping and multipopulation training data to improve cross-population polygenic risk scores

NATURE GENETICS

IF31.8

2022-04-07

OAAI

Weissbrod, Omer; Kanai, Masahiro; Shi, Huwenbo; Gazal, Steven; Peyrot, Wouter J.; Khera, Amit, V; Okada, Yukinori; Martin, Alicia R.; Finucane, Hilary K.; Price, Alkes L.

Misuse of the term 'trans-ethnic' in genomics research

NATURE GENETICS

IF31.8

2021-11-05

PREAI

Kamariza, Mireille; Crawford, Lorin; Jones, David; Finucane, Hilary

Direct characterization of cis-regulatory elements and functional dissection of complex genetic associations using HCR-FlowFISH 使用hcr-flowfish直接表征顺式调节元件和复杂遗传关联的功能解剖

NATURE GENETICS

IF31.8

2021-07-29

OAAI

Reilly, Steven K.; Gosai, Sager J.; Gutierrez, Alan; Mackay-Smith, Ava; Ulirsch, Jacob C.; Kanai, Masahiro; Mouri, Kousuke; Berenzy, Daniel; Kales, Susan; Butler, Gina M.; Gladden-Young, Adrianne; Bhuiyan, Redwan M.; Stitzel, Michael L.; Finucane, Hilary K.; Sabeti, Pardis C.; Tewhey, Ryan

Tractor uses local ancestry to enable the inclusion of admixed individuals in GWAS and to boost power

NATURE GENETICS

IF31.8

2021-01-18

121

OAAI

Atkinson, Elizabeth G.; Maihofer, Adam X.; Kanai, Masahiro; Martin, Alicia R.; Karczewski, Konrad J.; Santoro, Marcos L.; Ulirsch, Jacob C.; Kamatani, Yoichiro; Okada, Yukinori; Finucane, Hilary K.; Koenen, Karestan C.; Nievergelt, Caroline M.; Daly, Mark J.; Neale, Benjamin M.

Functionally informed fine-mapping and polygenic localization of complex trait heritability 复杂性状遗传力的功能信息精细定位和多基因定位

NATURE GENETICS

IF31.8

2020-11-16

149

OAAI

Weissbrod, Omer; Hormozdiari, Farhad; Benner, Christian; Cui, Ran; Ulirsch, Jacob; Gazal, Steven; Schoech, Armin P.; van de Geijn, Bryce; Reshef, Yakir; Marquez-Luna, Carla; O'Connor, Luke; Pirinen, Matti; Finucane, Hilary K.; Price, Alkes L.

Prioritizing disease and trait causal variants at the TNFAIP3 locus using functional and genomic features 使用功能和基因组特征对TNFAIP3基因座上的疾病和性状因果变异进行优先排序

NATURE COMMUNICATIONS

IF15.7

2020-03-06

OAAI

Ray, John P.; de Boer, Carl G.; Fulco, Charles P.; Lareau, Caleb A.; Kanai, Masahiro; Ulirsch, Jacob C.; Tewhey, Ryan; Ludwig, Leif S.; Reilly, Steven K.; Bergman, Drew T.; Engreitz, Jesse M.; Issner, Robbyn; Finucane, Hilary K.; Lander, Eric S.; Regev, Aviv; Hacohen, Nir

Genes with High Network Connectivity Are Enriched for Disease Heritability (vol 104, pg 896, 2019)

AMERICAN JOURNAL OF HUMAN GENETICS

IF8.1

2019-12-01

OAAI

Kim, Samuel S.; Dai, Chengzhen; Hormozdiari, Farhad; van de Geijn, Bryce; Gazal, Steven; Park, Yongjin; O'Connor, Luke; Amariuta, Tiffany; Loh, Po-Ru; Finucane, Hilary; Raychaudhuri, Soumya; Price, Alkes L.

Annotations capturing cell type-specific TF binding explain a large fraction of disease heritability

HUMAN MOLECULAR GENETICS

IF3.2

2019-10-09

OAAI

van de Geijn, Bryce; Finucane, Hilary; Gazal, Steven; Hormozdiari, Farhad; Amariuta, Tiffany; Liu, Xuanyao; Gusev, Alexander; Loh, Po-Ru; Reshef, Yakir; Kichaev, Gleb; Raychauduri, Soumya; Price, Alkes L.

研究方向