Robert L. Kortum

uniformed services university of the health sciences

H指数:26

被引数:2,424

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HRAS promotes mutant NRAS–driven transformation with codon and allele specificity

HRAS通过密码子和等位基因特异性促进突变NRAS驱动的转化

Science Signaling

IF6.6

2026-09-080

PRE

SOS1 inhibition suppresses the emergence of osimertinib resistance to generate a durable response in EGFR-mutant lung cancer

SOS1抑制可抑制奥希替尼耐药性的产生，从而在EGFR突变型肺癌中产生持久的疗效。

SCIENCE SIGNALING

IF6.6

2025-11-250

PRE

Wild-type RAS signaling is an essential therapeutic target in RAS-mutated cancers

野生型RAS信号传导是RAS突变型癌症中的一种关键治疗靶点。

Science Signaling

IF6.6

2025-09-160

PRE

Divergent proteogenomic gene expression is driven by microenvironment across tumor types

不同的蛋白质基因组基因表达是由不同肿瘤类型的微环境驱动的

CANCER RESEARCH

IF16.6

2024-03-220

PRE

Wild-type RAS signaling is an essential therapeutic target in RAS-mutated cancers

CANCER RESEARCH

IF16.6

2024-03-220

PRE

SOS2 modulates the threshold of EGFR signaling to regulate osimertinib efficacy and resistance in lung adenocarcinoma

MOLECULAR ONCOLOGY

IF4.5

2024-01-185

OAAI

SOS1 and KSR1 modulate MEK inhibitor responsiveness to target resistant cell populations based on PI3K and KRAS mutation status

SOS1和KSR1基于PI3K和KRAS突变状态调节MEK抑制剂对靶向耐药细胞群的反应性

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-11-168

OAAI

Wild-type RAS signaling is an essential therapeutic target in RAS-mutated cancers

MOLECULAR CANCER RESEARCH

IF4.7

2023-05-010

PRE

Tumor microenvironment differences between lung cancer subtypes revealed by spatial transcriptomics

空间转录组学揭示的肺癌亚型之间的肿瘤微环境差异

CANCER RESEARCH

IF16.6

2023-04-040

PRE

The molecular scaffold KSR1 regulates the proliferative and oncogenic potential of cells

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27147

OAAI

The molecular scaffold kinase suppressor of Ras 1 (KSR1) regulates adipogenesis

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-2777

OAAI

Kinase suppressor of Ras (KSR) is a scaffold which facilitates mitogen-activated protein kinase activation in vivo

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27277

OAAI

The molecular scaffold kinase suppressor of Ras 1 is a modifier of RasV12-induced and replicative senescence

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-2748

OAAI

Functional Redundancy of Sos1 and Sos2 for Lymphopoiesis and Organismal Homeostasis and Survival

Sos1和Sos2对淋巴细胞生成和机体稳态及生存的功能冗余

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-2047

OAAI

Kinase Suppressor of Ras 1 (KSR1) Regulates PGC1α and Estrogen-Related Receptor α To Promote Oncogenic Ras-Dependent Anchorage-Independent Growth

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-2046

OAAI

Deconstructing Ras Signaling in the Thymus

解构胸腺中的Ras信号

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-2043

OAAI

Caveolin-1 Is Required for Kinase Suppressor of Ras 1 (KSR1)-Mediated Extracellular Signal-Regulated Kinase 1/2 Activation, H-RasV12-Induced Senescence, and Transformation

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-2029

OAAI

Heterogeneity in RAS mutations: One size does not fit all

SCIENCE SIGNALING

IF6.6

2022-08-095

The oncogenic transcription factor FUS-CHOP can undergo nuclear liquid-liquid phase separation

JOURNAL OF CELL SCIENCE

IF3.6

2021-09-0329

Breaking Oncogene Addiction: Getting RTK/RAS-Mutated Cancers off the SOS

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2021-05-0720

PREAI

Robert L. Kortum

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