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L

Lawrence E. Samelson

national institutes of health (nih) - usa

88H指数
238论文数
2.9W被引数
收录论文 102
发表时间
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CD28 shapes T cell receptor signaling by regulating Lck dynamics and ZAP70 activationCD28通过调节Lck动力学和ZAP70激活来塑造T细胞受体信号传导
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2024-12-24
err0
errOAAI
errRaychaudhuri, Kumarkrishna; Rangu, Rohita; Ma, Alison; Alvinez, Neriah; Tran, Andy D.; Pallikkuth, Sandeep; Mcintire, Katherine M.; Garvey, Joseph A.; Yi, Jason; Samelson, Lawrence E.
err分享
err收藏
Generation of antitumor chimeric antigen receptors incorporating T cell signaling motifs
errSCIENCE SIGNALING
IF6.6
err2024-07-23
err1
errOAAI
errBalagopalan, Lakshmi; Moreno, Taylor; Qin, Haiying; Angeles, Benjamin C.; Kondo, Taisuke; Yi, Jason; McIntire, Katherine M.; Alvinez, Neriah; Pallikkuth, Sandeep; Lee, Mariah E.; Yamane, Hidehiro; Tran, Andy D.; Youkharibache, Philippe; Cachau, Raul E.; Taylor, Naomi; Samelson, Lawrence E.
err分享
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Inherited ARPC5 mutations cause an actinopathy impairing cell motility and disrupting cytokine signaling遗传性ARPC5突变导致放线菌病损害细胞运动并破坏细胞因子信号传导
errNATURE COMMUNICATIONS
IF15.7
err2023-06-22
err7
errOAAI
errNunes-Santos, Cristiane J.; Kuehn, HyeSun; Boast, Brigette; Hwang, SuJin; Kuhns, Douglas B.; Stoddard, Jennifer; Niemela, Julie E.; Fink, Danielle L.; Pittaluga, Stefania; Abu-Asab, Mones; Davies, John S.; Barr, Valarie A.; Kawai, Tomoki; Delmonte, Ottavia M.; Bosticardo, Marita; Garofalo, Mary; Carneiro-Sampaio, Magda; Somech, Raz; Gharagozlou, Mohammad; Parvaneh, Nima; Samelson, Lawrence E.; Fleisher, Thomas A.; Puel, Anne; Notarangelo, Luigi D.; Boisson, Bertrand; Casanova, Jean-Laurent; Derfalvi, Beata; Rosenzweig, Sergio D.
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Generation of novel anti-tumor chimeric antigen receptors incorporating downstream T-cell signaling proteins
errJOURNAL OF IMMUNOLOGY
IF3.4
err2023-05-01
err0
errOAAI
errAngeles, Benjamin C.; Moreno, Taylor; Balagopalan, Lakshmi; Yi, Jason; Qin, Haiying; Alvinez, Neriah; Yamane, Hide; Lee, Mariah; Pallikkuth, Sandeep; Tran, Andy; McIntire, Katherine; Taylor, Naomi; Samelson, Lawrence E.
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SLP-76 interaction with PLC-γ1 fine-tunes TCR signal strength for appropriate thymocyte selection, T cell homeostasis, and Ag-specific T cell response
errJOURNAL OF IMMUNOLOGY
IF3.4
err2023-05-01
err0
errOAAI
errStassenko, Elizabeth; Wada, Junya; Lee, Mariah; Li, Wenmei; Balagopalan, Lakshmi; Evans, Christine; Hagenau, Herbert; Awasthi, Parirokh; Chari, Raj; Yamane, Hidehiro; Samelson, Lawrence E.
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Genetic evidence for differential coupling of Syk family kinases to the T-cell receptor: Reconstitution studies in a ZAP-70-deficient jurkat T-Cell line
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-28
err259
errOAAI
errWilliams, BL; Schreiber, KL; Zhang, WG; Wange, RL; Samelson, LE; Leibson, PJ; Abraham, RT
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err收藏
Persistence of cooperatively stabilized signaling clusters drives T-cell activation
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err136
errOAAI
errBunnell, Stephen C.; Singer, Andrew L.; Hong, David I.; Jacque, Berri H.; Jordan, Martha S.; Seminario, Maria-Cristina; Barr, Valarie A.; Koretzky, Gary A.; Samelson, Lawrence E.
err分享
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c-Cbl-mediated regulation of LAT-nucleated signaling complexes
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err112
errOAAI
errBalagopalan, Lakshmi; Barr, Valarie A.; Sommers, Connie L.; Barda-Saad, Mira; Goyal, Amrita; Isakowitz, Matthew S.; Samelson, Lawrence E.
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err收藏
Functional Redundancy of Sos1 and Sos2 for Lymphopoiesis and Organismal Homeostasis and SurvivalSos1和Sos2对淋巴细胞生成和机体稳态及生存的功能冗余
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-20
err47
errOAAI
errBaltanas, Fernando C.; Perez-Andres, Martin; Ginel-Picardo, Alicia; Diaz, David; Jimeno, David; Liceras-Boillos, Pilar; Kortum, Robert L.; Samelson, Lawrence E.; Orfao, Alberto; Santos, Eugenio
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err收藏
Deconstructing Ras Signaling in the Thymus解构胸腺中的Ras信号
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-20
err43
errOAAI
errKortum, Robert L.; Sommers, Connie L.; Pinski, John M.; Alexander, Clayton P.; Merrill, Robert K.; Li, Wenmei; Love, Paul E.; Samelson, Lawrence E.
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Multipoint Binding of the SLP-76 SH2 Domain to ADAP Is Critical for Oligomerization of SLP-76 Signaling Complexes in Stimulated T Cells
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-20
err49
errOAAI
errCoussens, Nathan P.; Hayashi, Ryo; Brown, Patrick H.; Balagopalan, Lakshmi; Balbo, Andrea; Akpan, Itoro; Houtman, Jon C. D.; Barr, Valarie A.; Schuck, Peter; Appella, Ettore; Samelson, Lawrence E.
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In vitro reconstitution reveals cooperative mechanisms of adapter protein-mediated activation of phospholipase C-gamma1 in T cells
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2023-01-01
err1
errOAAI
errWada, Junya; Rathnayake, Udumbara; Jenkins, Lisa; Mohammadi, Moosa; Appella, Ettore; Randazzo, Paul; Samelson, Lawrence
err分享
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In vitro reconstitution reveals cooperative mechanisms of adapter protein-mediated activation of phospholipase C-γ1 in T cells
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2022-03-01
err4
errOAAI
errWada, Junya; Rathnayake, Udumbara; Jenkins, Lisa M.; Singh, Avinash; Mohammadi, Moosa; Appella, Ettore; Randazzo, Paul A.; Samelson, Lawrence E.
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Expression of a TMC6-TMC8-CIB1 heterotrimeric complex in lymphocytes is regulated by each of the components
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2020-11-01
err8
errOAAI
errWu, Chuan-Jin; Li, Xing; Sommers, Connie L.; Kurima, Kiyoto; Huh, Sunmee; Bugos, Grace; Dong, Lijin; Li, Wenmei; Griffith, Andrew J.; Samelson, Lawrence E.
err分享
err收藏
Pak1 Kinase Promotes Activated T Cell Trafficking by Regulating the Expression of L-Selectin andPak1激酶通过调节L-选择素和
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2019-03-05
err4
errOAAI
errDios-Esponera, Ana; Melis, Nicolas; Subramanian, Bhagawat C.; Weigert, Roberto; Samelson, Lawrence E.
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TCR microclusters form spatially segregated domains and sequentially assemble in calcium-dependent kinetic steps
errNATURE COMMUNICATIONS
IF15.7
err2019-01-17
err64
errOAAI
errYi, Jason; Balagopalan, Lakshmi; Nguyen, Tiffany; McIntire, Katherine M.; Samelson, Lawrence E.
err分享
err收藏
Cooperative assembly of a four-molecule signaling complex formed upon T cell antigen receptor activationT细胞抗原受体激活后形成的四分子信号复合物的协同组装
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2018-12-03
err17
errOAAI
errManna, Asit; Zhao, Huaying; Wada, Junya; Balagopalan, Lakshmi; Tagad, Harichandra D.; Appella, Ettore; Schuck, Peter; Samelson, Lawrence E.
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err收藏
Timed Regulation of 3BP2 Induction Is Critical for Sustaining CD8+ T Cell Expansion and Differentiation
errCELL REPORTS
IF6.9
err2018-07-01
err10
errOAAI
errDimitriou, Ioannis D.; Lee, Korris; Akpan, Itoro; Lind, Evan F.; Barr, Valarie A.; Ohashi, Pamela S.; Samelson, Lawrence E.; Rottapel, Robert
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Plasma membrane LAT activation precedes vesicular recruitment defining two phases of early T-cell activation
errNATURE COMMUNICATIONS
IF15.7
err2018-05-22
err33
errOAAI
errBalagopalan, Lakshmi; Yi, Jason; Nguyen, Tiffany; McIntire, Katherine M.; Harned, Adam S.; Narayan, Kedar; Samelson, Lawrence E.
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The Cish SH2 domain is essential for PLC-γ1 regulation in TCR stimulated CD8+ T cells
errSCIENTIFIC REPORTS
IF3.9
err2018-03-28
err22
errOAAI
errGuittard, Geoffrey; Dios-Esponera, Ana; Palmer, Douglas C.; Akpan, Itoro; Barr, Valarie A.; Manna, Asit; Restifo, Nicholas P.; Samelson, Lawrence E.
err分享
err收藏

研究方向

暂无研究方向
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