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Rubén Vidal

indiana university school of medicine
H指数:51
被引数:1.1万

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Phosphorylation at serine 214 correlates with tau seeding activity in an age-dependent manner in two mouse models for tauopathies and is required for tau transsynaptic propagation

在两种tau蛋白病小鼠模型中,丝氨酸214位点的磷酸化与tau蛋白的成核活性呈年龄依赖性相关,并且是tau蛋白跨突触传播所必需的。

2025-09-010
OAAI
Tau depletion diminishes vascular amyloid‐related deficits in a mouse model of cerebral amyloid angiopathy

Tau耗竭减轻了小鼠脑淀粉样血管病模型中血管淀粉样蛋白相关的缺陷。Alzheimers Dement. 21:e70238

2025-05-090
OAAI
γ-Secretase modulator resistance of an aggressive Alzheimer-causing presenilin mutant can be overcome in the heterozygous patient state by a set of advanced compounds (vol 17, 49, 2025)

γ-分泌酶调节剂抵抗性在一种具有攻击性的阿尔茨海默病致病性早衰素突变体中,可以通过一组先进化合物在杂合患者状态下被克服(卷17,49,2025)

2025-04-150
OA
New SNCA mutation and structures of α-synuclein filaments from juvenile-onset synucleinopathy

来自青少年发作的突触核蛋白病的新的SNCA突变和 α-突触核蛋白丝的结构

2023-02-2727
OAAI