Steve Gentleman - Publications, H-index & Citations

Steve Gentleman

Hammersmith Hospital

49H指数

159论文数

1.1W被引数

收录论文 71

发表时间

Novel in situ seeding immunodetection assay uncovers neuronal-driven alpha-synuclein seeding in Parkinson’s disease 一种新型的原位播种免疫检测方法揭示了帕金森病中神经元驱动的α-突触核蛋白播种。

npj Parkinson's Disease

IF0

2025-08-25

OAAI

Maria Otero-Jimenez; Marcelina J. Wojewska; Simona Jogaudaite; David Miller; Sandra Gray-Rodriguez; Grainne C. Geoghegan; Laura Abelleira-Hervas; Tim James Viney; Barbara Sarkany; Djordje Gveric; Steve Gentleman; Javier Alegre-Abarrategui

Type-Specific Single-Neuron Analysis Reveals Mitochondrial DNA Maintenance Failure Affecting Atrophying Pontine Neurons Differentially in Lewy Body Dementia Syndromes 类型特异性单神经元分析揭示路易体痴呆综合征中影响萎缩脑桥神经元的线粒体DNA维持差异失败

Aging Cell

IF7.1

2025-06-06

OAAI

Eloise J. Stephenson; Laura J. Bailey; Stephen Gentleman; Helen Tuppen; Istvan Bodi; Claire Troakes; Christopher M. Morris; Tony M. Carr; Sarah Guthrie

Stereological analysis of cholinergic neurons within bilateral pedunculopontine nuclei in health and when affected by Parkinson's disease 胆碱能神经元在双侧脚桥核中的体视学分析，以及帕金森病影响下的情况

BRAIN PATHOLOGY

IF6.2

2025-04-15

PREAI

Puneet Kumar Sharma; Steve Gentleman; David Trevor Dexter; Ilse Sanet Pienaar

Neuropathological stages of neuronal, astrocytic and oligodendrocytic alpha-synuclein pathology in Parkinson's disease 帕金森氏病中神经元，星形胶质细胞和少突胶质细胞 α-突触核蛋白病理学的神经病理学阶段

ACTA NEUROPATHOLOGICA COMMUNICATIONS

IF5.7

2025-02-11

OAAI

Otero-Jimenez, Maria; Wojewska, Marcelina J.; Binding, Lawrence P.; Jogaudaite, Simona; Gray-Rodriguez, Sandra; Young, Alexandra L.; Gentleman, Steve; Alegre-Abarrategui, Javier

Cardiovascular risk and obesity impact loss of grey matter volume earlier in males than females

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

IF7.5

2024-11-27

OAAI

Nowell, Joseph; Gentleman, Steve; Edison, Paul

Biomarker-Based Approach to α-Synucleinopathies: Lessons from Neuropathology 基于生物标志物的 α-突触核蛋白病方法: 神经病理学的教训

MOVEMENT DISORDERS

IF7.6

2024-10-03

OAAI

Kovacs, Gabor G.; Grinberg, Lea T.; Halliday, Glenda; Alafuzoff, Irina; Dugger, Brittany N.; Murayama, Shigeo; Forrest, Shelley L.; Martinez-Valbuena, Ivan; Tanaka, Hidetomo; Kon, Tomoya; Yoshida, Koji; Jaunmuktane, Zane; Spina, Salvatore; Nelson, Peter T.; Gentleman, Steve; Alegre-Abarrategui, Javier; Serrano, Geidy E.; Paes, Vitor Ribeiro; Takao, Masaki; Wakabayashi, Koichi; Uchihara, Toshiki; Yoshida, Mari; Saito, Yuko; Kofler, Julia; Rodriguez, Roberta Diehl; Gelpi, Ellen; Attems, Johannes; Crary, John F.; Seeley, William W.; Duda, John E.; Keene, C. Dirk; Woulfe, John; Munoz, David; Smith, Colin; Lee, Edward B.; Neumann, Manuela; White, Charles L.; Mckee, Ann C.; Thal, Dietmar R.; Jellinger, Kurt; Ghetti, Bernardino; Mackenzie, Ian R. A.; Dickson, Dennis W.; Beach, Thomas G.

Do Tau Deposition and Glucose Metabolism Dissociate in Alzheimer's Disease Trajectory?Tau沉积和葡萄糖代谢在阿尔茨海默病轨迹中解离吗？

JOURNAL OF ALZHEIMERS DISEASE

IF3.1

2024-09-24

PREAI

Nowell, Joseph; Raza, Sanara; Livingston, Nicholas R.; Sivanathan, Shayndhan; Gentleman, Steve; Edison, Paul

Combined Neuroinflammation and Amyloid PET Markers in Predicting Disease Progression in Cognitively Impaired Subjects 神经炎症和淀粉样蛋白PET标志物联合预测认知受损受试者的疾病进展

JOURNAL OF ALZHEIMERS DISEASE

IF3.1

2024-07-13

PREAI

Leng, Fangda; Hinz, Rainer; Gentleman, Steve; Dani, Melanie; Brooks, David J.; Edison, Paul

Associations of amyloid-β oligomers and plaques with neuropathology in the AppNL-G-F mouse

BRAIN COMMUNICATIONS

IF4.5

2024-06-25

OAAI

Tang, Jiabin; Huang, Helen; Muirhead, Robert C. J.; Zhou, Yue; Li, Junheng; DeFelice, John; Kopanitsa, Maksym, V; Serneels, Lutgarde; Davey, Karen; Tilley, Bension S.; Gentleman, Steve; Matthews, Paul M.

Differential methylation analysis in neuropathologically confirmed dementia with Lewy bodies

COMMUNICATIONS BIOLOGY

IF5.1

2024-01-05

OAAI

Reho, Paolo; Saez-Atienzar, Sara; Ruffo, Paola; Solaiman, Sultana; Shah, Zalak; Chia, Ruth; Kaivola, Karri; Traynor, Bryan J.; Tilley, Bension S.; Gentleman, Steve M.; Hodges, Angela K.; Aarsland, Dag; Monuki, Edwin S.; Newell, Kathy L.; Woltjer, Randy; Albert, Marilyn S.; Dawson, Ted M.; Rosenthal, Liana S.; Troncoso, Juan C.; Pletnikova, Olga; Serrano, Geidy E.; Beach, Thomas G.; Easwaran, Hariharan P.; Scholz, Sonja W.

Linking environmental risk factors with epigenetic mechanisms in Parkinson's disease

NPJ PARKINSONS DISEASE

IF8.2

2023-08-25

OAAI

Tsalenchuk, Maria; Gentleman, Steve M.; Marzi, Sarah J.

Glycogen Synthase Kinase 3 Inhibition Promotes Lysosomal Biogenesis and Autophagic Degradation of the Amyloid-β Precursor Protein

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-20

152

OAAI

Parr, Callum; Carzaniga, Raffaela; Gentleman, Steve M.; Van Leuven, Fred; Walter, Jochen; Sastre, Magdalena

Glycogen Synthase Kinase 3 Inhibition Promotes Lysosomal Biogenesis and Autophagic Degradation of the Amyloid-β Precursor Protein (vol 32, pg 4410, 2012)

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-17

OAAI

Parr, Callum; Carzaniga, Raffaela; Gentleman, Steve M.; Van Leuven, Fred; Walter, Jochen; Sastre, Magdalena

Different MAPT haplotypes influence expression of total MAPT in postmortem brain tissue

ACTA NEUROPATHOLOGICA COMMUNICATIONS

IF5.7

2023-03-11

OAAI

Tauber, Christina V.; Schwarz, Sigrid C.; Roesler, Thomas W.; Arzberger, Thomas; Gentleman, Steve; Windl, Otto; Krumbiegel, Mandy; Reis, Andre; Ruf, Viktoria C.; Herms, Jochen; Hoeglinger, Guenter U.

Neuroinflammation is independently associated with brain network dysfunction in Alzheimer's disease 神经炎症与阿尔茨海默病的脑网络功能障碍独立相关

MOLECULAR PSYCHIATRY

IF10.1

2022-12-06

OAAI

Leng, Fangda; Hinz, Rainer; Gentleman, Steve; Hampshire, Adam; Dani, Melanie; Brooks, David J.; Edison, Paul

Common signatures of differential microRNA expression in Parkinson's and Alzheimer's disease brains

BRAIN COMMUNICATIONS

IF4.5

2022-10-28

OAAI

Dobricic, Valerija; Schilling, Marcel; Farkas, Ildiko; Gveric, Djordje O.; Ohlei, Olena; Schulz, Jessica; Middleton, Lefkos; Gentleman, Steve M.; Parkkinen, Laura; Bertram, Lars; Lill, Christina M.

Mitochondrial dysfunction is a key pathological driver of early stage Parkinson's 线粒体功能障碍是早期帕金森病的关键病理驱动因素

ACTA NEUROPATHOLOGICA COMMUNICATIONS

IF5.7

2022-09-08

OAAI

Toomey, Christina E.; Heywood, Wendy E.; Evans, James R.; Lachica, Joanne; Pressey, Sarah N.; Foti, Sandrine C.; Al Shahrani, Mesfer; D'Sa, Karishma; Hargreaves, Iain P.; Heales, Simon; Orford, Michael; Troakes, Claire; Attems, Johannes; Gelpi, Ellen; Palkovits, Miklos; Lashley, Tammaryn; Gentleman, Steve M.; Revesz, Tamas; Mills, Kevin; Gandhi, Sonia

Multisystem screening reveals SARS-CoV-2 in neurons of the myenteric plexus and in megakaryocytes

JOURNAL OF PATHOLOGY

IF5.2

2022-03-31

OAAI

Gray-Rodriguez, Sandra; Jensen, Melanie P.; Otero-Jimenez, Maria; Hanley, Brian; Swann, Olivia C.; Ward, Patrick A.; Salguero, Francisco J.; Querido, Nadira; Farkas, Ildiko; Velentza-Almpani, Elisavet; Weir, Justin; Barclay, Wendy S.; Carroll, Miles W.; Jaunmuktane, Zane; Brandner, Sebastian; Pohl, Ute; Allinson, Kieren; Thom, Maria; Troakes, Claire; Al-Sarraj, Safa; Sastre, Magdalena; Gveric, Djordje; Gentleman, Steve; Roufosse, Candice; Osborn, Michael; Alegre-Abarrategui, Javier

Relationship between astrocyte reactivity, using novel 11C-BU99008 PET, and glucose metabolism, grey matter volume and amyloid load in cognitively impaired individuals

MOLECULAR PSYCHIATRY

IF10.1

2022-02-07

OAAI

Livingston, Nicholas R.; Calsolaro, Valeria; Hinz, Rainer; Nowell, Joseph; Raza, Sanara; Gentleman, Steve; Tyacke, Robin J.; Myers, Jim; Venkataraman, Ashwin V.; Perneczky, Robert; Gunn, Roger N.; Rabiner, Eugenii A.; Parker, Christine A.; Murphy, Philip S.; Wren, Paul B.; Nutt, David J.; Matthews, Paul M.; Edison, Paul

Diverse human astrocyte and microglial transcriptional responses to Alzheimer's pathology 不同的人类星形胶质细胞和小胶质细胞对阿尔茨海默氏病的转录反应

ACTA NEUROPATHOLOGICA

IF9.3

2021-11-12

OAAI

Smith, Amy M.; Davey, Karen; Tsartsalis, Stergios; Khozoie, Combiz; Fancy, Nurun; Tang, See Swee; Liaptsi, Eirini; Weinert, Maria; McGarry, Aisling; Muirhead, Robert C. J.; Gentleman, Steve; Owen, David R.; Matthews, Paul M.

研究方向