Ksenia V. Kastanenka - Publications, H-index & Citations

Ksenia V. Kastanenka

Mass General Brigham and Harvard Medical School

17H指数

52论文数

3.4K被引数

收录论文 24

发表时间

Compartment-specific analysis reveals disrupted astrocytic calcium transients in anesthetized Alzheimer's disease mice 亚室特异性分析揭示了麻醉阿尔茨海默病小鼠中星形胶质细胞钙瞬变的紊乱

JOURNAL OF ALZHEIMERS DISEASE

IF3.1

2026-06-30

PREAI

Md Joynal Abedin; Yee Fun Lee; Melinda Zhang; Alyssa N Russ; Dmitry Gerashchenko; Brian J. Bacskai; Ksenia V. Kastanenka

Materials Today

IF22

2026-06-13

PREAI

Hyejin Chang; Homan Kang; Seung-Ki Lee; Jaehong Lim; Ksenia V. Kastanenka; Satoshi Kashiwagi; Bong-Hyun Jun

Zolpidem restores sleep and decreases amyloid in a mouse model 唑吡坦恢复睡眠并减少小鼠模型中的淀粉样蛋白

alzheimer's & dementia

IF0

2026-03-11

OAAI

Lu Yu; Shinya Yokomizo; Tri H. Doan; Qiuchen Zhao; Akshatha Ganne; Meenakshisundaram Balasubramaniam; Ksenia V. Kastanenka

The role of astrocytes in Alzheimer's disease: Pathophysiology, biomarkers, and therapeutic potential 星形胶质细胞在阿尔茨海默病中的作用：病理生理学、生物标志物和治疗潜力

Journal of Alzheimer’s Disease

IF0

2026-01-13

PREAI

Md Joynal Abedin; Ksenia V. Kastanenka

Transplantation of GABAergic Interneuron Progenitors Restores Cortical Circuit Function in an Alzheimer's Disease Mouse Model GABAergic interneuron前体细胞移植恢复了阿尔茨海默病小鼠模型中的皮层回路功能

ADVANCED SCIENCE

IF14.1

2025-11-01

OAAI

Yokomizo, Shinya; Maci, Megi; Stafford, April M.; Miller, Morgan R.; Perle, Stephen J.; Inagaki, Shuzo; Takahashi, Shusaku; Brown-harding, Heather; Liang, Linda; Lovely, Alex; Algamal, Moustafa; Gillani, Rebecca L.; Zwang, Theodore J.; Richardson, Douglas; Naegele, Janice R.; Vogt, Daniel; Kastanenka, Ksenia V.

Protective exercise responses in the dentate gyrus of Alzheimer’s disease mouse model revealed with single-nucleus RNA-sequencing 阿尔茨海默病小鼠模型齿状回中保护性运动反应的单核RNA测序揭示

Nature Neuroscience

IF20

2025-06-12

PREAI

Joana F. da Rocha; Michelle L. Lance; Renhao Luo; Pius Schlachter; Luis Moreira; Mohamed Ariff Iqbal; Paula Kuhn; Robert S. Gardner; Sophia Valaris; Mohammad R. Islam; Gabriele M. Gassner; Sofia Mazuera; Kaela Healy; Sanjana Shastri; Nathaniel B. Hibbert; Kristen V. Moran-Figueroa; Erin B. Haley; Ryan D. Pfeiffer; Sema Aygar; Ksenia V. Kastanenka; Logan Brase; Oscar Harari; Bruno A. Benitez; Nathan R. Tucker; Christiane D. Wrann

Optogenetic targeting of cortical astrocytes selectively improves NREM sleep in an Alzheimer's disease mouse model 皮质星形胶质细胞的光遗传学靶向选择性改善阿尔茨海默病小鼠模型中的NREM睡眠

SCIENTIFIC REPORTS

IF3.9

2024-10-04

OAAI

Zhao, Qiuchen; Yokomizo, Shinya; Perle, Stephen J.; Lee, Yee Fun; Zhou, Heng; Miller, Morgan R.; Li, Hanyan; Gerashchenko, Dmitry; Gomperts, Stephen N.; Bacskai, Brian J.; Kastanenka, Ksenia V.

NB-02 Protects Neurons and Astrocytes from Oligomeric Amyloid-β-Mediated Damage

JOURNAL OF ALZHEIMERS DISEASE

IF3.1

2024-05-14

PREAI

Miller, Morgan R.; Lariviere, Lavender; Pagnier, Guillaume J.; Aygar, Sema; Wieckiewicz, Natalia; Maesako, Masato; Bacskai, Brian J.; Kastanenka, Ksenia V.

OPTOGENETIC RESCUE OF SLEEP SLOWS ALZHEIMER'S PROGRESSION IN A MOUSE MODEL

SLEEP

IF4.9

2024-04-20

PREAI

Kastanenka, Ksenia

Sleep restoration by optogenetic targeting of GABAergic neurons reprograms microglia and ameliorates pathological phenotypes in an Alzheimer's disease model 通过gaba能神经元的光遗传学靶向恢复睡眠在阿尔茨海默病模型中重新编程小胶质细胞并改善病理表型

MOLECULAR NEURODEGENERATION

IF17.5

2023-12-01

OAAI

Zhao, Qiuchen; Maci, Megi; Miller, Morgan R.; Zhou, Heng; Zhang, Fang; Algamal, Moustafa; Lee, Yee Fun; Hou, Steven S.; Perle, Stephen J.; Le, Hoang; Russ, Alyssa N.; Lo, Eng H.; Gerashchenko, Dmitry; Gomperts, Stephen N.; Bacskai, Brian J.; Kastanenka, Ksenia V.

Building transformers from neurons and astrocytes

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-08-14

OAAI

Kozachkov, Leo; Kastanenka, Ksenia V.; Krotov, Dmitry

Optogenetic targeting of astrocytes restores slow brain rhythm function and slows Alzheimer's disease pathology 星形胶质细胞的光遗传学靶向恢复缓慢的脑节律功能并减缓阿尔茨海默氏病的病理

SCIENTIFIC REPORTS

IF3.9

2023-08-11

OAAI

Lee, Yee Fun; Russ, Alyssa N.; Zhao, Qiuchen; Perle, Stephen J.; Maci, Megi; Miller, Morgan R.; Hou, Steven S.; Algamal, Moustafa; Zhao, Zhuoyang; Li, Hanyan; Gelwan, Noah; Liu, Zhe; Gomperts, Stephen N.; Araque, Alfonso; Galea, Elena; Bacskai, Brian J.; Kastanenka, Ksenia V.

Calcium sensor Yellow Cameleon 3.6 as a tool to support the calcium hypothesis of Alzheimer's disease 钙传感器黄色Cameleon 3.6作为支持阿尔茨海默病钙假说的工具

ALZHEIMERS & DEMENTIA

IF11.1

2023-05-08

OAAI

Miller, Morgan R.; Lee, Yee Fun; Kastanenka, Ksenia V.

Reduced excitatory neuron activity and interneuron-type-specific deficits in a mouse model of Alzheimer's disease

COMMUNICATIONS BIOLOGY

IF5.1

2022-12-02

OAAI

Algamal, Moustafa; Russ, Alyssa N. N.; Miller, Morgan R. R.; Hou, Steven S. S.; Maci, Megi; Munting, Leon P. P.; Zhao, Qiuchen; Gerashchenko, Dmitry; Bacskai, Brian J. J.; Kastanenka, Ksenia V. V.

Low frequency visual stimulation enhances slow wave activity without disrupting the sleep pattern in mice

SCIENTIFIC REPORTS

IF3.9

2022-07-19

OAAI

Thankachan, Stephen; Yang, Chun; Kastanenka, Ksenia, V; Bacskai, Brian J.; Gerashchenko, Dmitry

Slow Wave Sleep Is a Promising Intervention Target for Alzheimer's Disease 慢波睡眠是阿尔茨海默病的有希望的干预目标

FRONTIERS IN NEUROSCIENCE

IF3.2

2020-06-30

OAAI

Lee, Yee Fun; Gerashchenko, Dmitry; Timofeev, Igor; Bacskai, Brian J.; Kastanenka, Ksenia V.

Frequency-dependent exacerbation of Alzheimer's disease neuropathophysiology

SCIENTIFIC REPORTS

IF3.9

2019-06-20

OAAI

Kastanenka, Ksenia, V; Calvo-Rodriguez, Maria; Hou, Steven S.; Zhou, Heng; Takeda, Shuko; Arbel-Ornath, Michal; Lariviere, Amanda; Lee, Yee Fun; Kim, Alex; Hawkes, Jonathan M.; Logan, Robert; Feng, Danielle; Chen, Xiqun; Gomperts, Stephen N.; Bacskai, Brian J.

A roadmap to integrate astrocytes into Systems Neuroscience

GLIA

IF5.1

2019-05-06

OAAI

Kastanenka, Ksenia V.; Moreno-Bote, Ruben; De Pitta, Maurizio; Perea, Gertrudis; Eraso-Pichot, Abel; Masgrau, Roser; Poskanzer, Kira E.; Galea, Elena

CRISPR/Cas9 Mediated Disruption of the Swedish APP Allele as a Therapeutic Approach for Early-Onset Alzheimer's Disease

MOLECULAR THERAPY-NUCLEIC ACIDS

IF0

2018-06-01

129

OAAI

Gyorgy, Bence; Loov, Camilla; Zaborowski, Mikolaj P.; Takeda, Shuko; Kleinstiver, Benjamin P.; Commins, Caitlin; Kastanenka, Ksenia; Mu, Dakai; Volak, Adrienn; Giedraitis, Vilmantas; Lannfelt, Lars; Maguire, Casey A.; Joung, J. Keith; Hyman, Bradley T.; Breakefield, Xandra O.; Ingelsson, Martin

An acute functional screen identifies an effective antibody targeting amyloid-β oligomers based on calcium imaging

SCIENTIFIC REPORTS

IF3.9

2018-03-15

OAAI

Wang, Xueying; Kastanenka, Ksenia V.; Arbel-Ornath, Michal; Commins, Caitlin; Kuzuya, Akira; Lariviere, Amanda J.; Krafft, Grant A.; Hefti, Franz; Jerecic, Jasna; Bacskai, Brian J.

研究方向