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M

Manuel Schweighauser

Medical Research Council Laboratory of Molecular Biology
H指数:18
被引数:3,661

个人简介

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教育背景

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工作经历

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荣誉奖项

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Cryo-EM structures of amyloid-β filaments with the Arctic mutation (E22G) from human and mouse brains

人类和小鼠大脑中具有北极突变 (E22G) 的淀粉样 β 丝的cryo-em结构

ACTA NEUROPATHOLOGICA
IF9.3
2023-01-0730
OAAI
Yang, Yang; Zhang, Wenjuan; Murzin, Alexey G.; Schweighauser, Manuel; Huang, Melissa; Lovestam, Sofia; Peak-Chew, Sew Y.; Saito, Takashi; Saido, Takaomi C.; Macdonald, Jennifer; Lavenir, Isabelle; Ghetti, Bernardino; Graff, Caroline; Kumar, Amit; Nordberg, Agneta; Goedert, Michel; Scheres, Sjors H. W.
Structures of α-synuclein filaments from human brains with Lewy pathology

具有Lewy病理学的人脑 α-突触核蛋白细丝的结构

Nature
IF48.5
2022-09-150
PREAI
Yang Yang; Yang Shi; Manuel Schweighauser; Xianjun Zhang; Abhay Kotecha; Alexey G. Murzin; Holly J. Garringer; Patrick W. Cullinane; Yuko Saito; Tatiana Foroud; Thomas T. Warner; Kazuko Hasegawa; Ruben Vidal; Shigeo Murayama; Tamas Revesz; Bernardino Ghetti; Masato Hasegawa; Tammaryn Lashley; Sjors H. W. Scheres; Michel Goedert
Signatures of glial activity can be detected in the CSF proteome
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2022-06-0613
OA
Eninger, Timo; Mueller, Stephan A.; Bacioglu, Mehtap; Schweighauser, Manuel; Lambert, Marius; Maia, Luis F.; Neher, Jonas J.; Hornfeck, Sarah M.; Obermueller, Ulrike; Kleinberger, Gernot; Haass, Christian; Kahle, Philipp J.; Staufenbiel, Matthias; Ping, Lingyan; Duong, Duc M.; Levey, Allan, I; Seyfried, Nicholas T.; Lichtenthaler, Stefan F.; Jucker, Mathias; Kaeser, Stephan A.
Age-dependent formation of TMEM106B amyloid filaments in human brains
Nature
IF48.5
2022-03-280
OAAI
Manuel Schweighauser; Diana Arseni; Mehtap Bacioglu; Melissa Huang; Sofia Lövestam; Yang Shi; Yang Yang; Wenjuan Zhang; Abhay Kotecha; Holly J. Garringer; Ruben Vidal; Grace I. Hallinan; Kathy L. Newell; Airi Tarutani; Shigeo Murayama; Masayuki Miyazaki; Yuko Saito; Mari Yoshida; Kazuko Hasegawa; Tammaryn Lashley; Tamas Revesz; Gabor G. Kovacs; John van Swieten; Masaki Takao; Masato Hasegawa; Bernardino Ghetti; Maria Grazia Spillantini; Benjamin Ryskeldi-Falcon; Alexey G. Murzin; Michel Goedert; Sjors H. W. Scheres
Microglial inclusions and neurofilament light chain release follow neuronal α-synuclein lesions in long-term brain slice cultures

在长期脑片培养中，神经元 α-突触核蛋白损伤后小胶质细胞内含物和神经丝轻链释放

MOLECULAR NEURODEGENERATION
IF17.5
2021-08-1120
OAAI
Barth, Melanie; Bacioglu, Mehtap; Schwarz, Niklas; Novotny, Renata; Brandes, Janine; Welzer, Marc; Mazzitelli, Sonia; Haesler, Lisa M.; Schweighauser, Manuel; Wuttke, Thomas, V; Kronenberg-Versteeg, Deborah; Fog, Karina; Ambjorn, Malene; Alik, Ania; Melki, Ronald; Kahle, Philipp J.; Shimshek, Derya R.; Koch, Henner; Jucker, Mathias; Tanrioever, Gaye
Structures of α-synuclein filaments from multiple system atrophy

来自多系统萎缩的 α-突触核蛋白细丝的结构

Nature
IF48.5
2020-05-270
PREAI
Manuel Schweighauser; Yang Shi; Airi Tarutani; Fuyuki Kametani; Alexey G. Murzin; Bernardino Ghetti; Tomoyasu Matsubara; Taisuke Tomita; Takashi Ando; Kazuko Hasegawa; Shigeo Murayama; Mari Yoshida; Masato Hasegawa; Sjors H. W. Scheres; Michel Goedert

研究方向

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M
Michel Goedert
H 指数:146论文数:574被引数:9.2万
S
Sjors H. W. Scheres
H 指数:84论文数:367被引数:4.9万
B
Bernardino Ghetti
H 指数:121论文数:916被引数:6.8万
M
Mehtap Bacioglu
H 指数:10论文数:22被引数:1,081
P
Philipp J. Kahle
H 指数:63论文数:173被引数:1.5万
M
Mathias Jucker
H 指数:93论文数:401被引数:3.8万
D
Derya R. Shimshek
H 指数:37论文数:82被引数:4,973
H
Holly J. Garringer
H 指数:32论文数:95被引数:9,172
A
Alexey G. Murzin
H 指数:59论文数:204被引数:2.6万
L
Luı́s F. Maia
H 指数:26论文数:76被引数:4,728