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M

Margaret A. Brimble

the university of auckland

52H指数
1.0K论文数
1.6W被引数
收录论文 272
发表时间
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Thia-Michael Stapling of Allenamide-Incorporated α-Helical Antimicrobial Peptides含烯酰胺基团的α-螺旋抗菌肽的硫-Michael加成环化反应
errThe Journal of Organic Chemistry
IF3.6
err2026-07-02
err0
PREAI
errTae-Ung Na; Shannon Macdonald; Polly Chuanrong Sun; Margaret A. Brimble; Thomas K. Proft; Catherine J. Tsai; Alan J. Cameron
err分享
err收藏
Elucidation of the Conformational Rate Processes of the Macrocyclic Lactone (–)-Nonenolide Through Variable Temperature NMR, Quantum Mechanics, and Molecular Dynamics通过变温NMR、量子力学和分子动力学阐明大环内酯（–）-壬烯内酯的构象速率过程
errEuropean Journal of Organic Chemistry
IF2.7
err2026-04-10
err0
errOAAI
errIngso Limbu; Liam R. Hunt; Daniel P. Furkert; Margaret A. Brimble; Mary J. Garson; Elizabeth H. Krenske
err分享
err收藏
Introducing CLipPA Lipid Chemodiversity to Enzymatically Truncated Polymyxin B: A Soft Drug Strategy to Combat Gram-Negative Pathogens
errrsc med. chem.
IF0
err2026-02-07
err0
PREAI
errTae-Ung Na; Yann Hermant; Andrew Siow; Jeremy George Owen; Susanna Chan; Gavin Frank Painter; Cameron C Hanna; Zillah Daysh; Beatrix L Goggin; Jane R. Allison; Veronika Sander; Alan J Davidson; Georgia Campbell; Scott A. Ferguson; Gregory M Cook; Paul Harris; Margaret A Brimble; Alan James Cameron
err分享
err收藏
Synthesis of the Antifungal and Antiviral Cyclic Lipodepsipeptides Verlamelins A and B抗真菌和抗病毒环脂肽类化合物Verlamelins A和B的合成
errJournal of Organic Chemistry
IF3.6
err2026-02-01
err0
PREAI
errPalpal-latoc, Dennise; Hauk, Bernhard N.; Rajchakit, Urawadee; Lin, Yongqi; Yang, Sung-Hyun; Stubbing, Louise A.; Li, Freda F.; Cameron, Alan J.; Brimble, Margaret A.
err分享
err收藏
Design; synthesis and biological activity of potential retrometabolic polymyxins via thiol–ene chemistry设计；通过硫醇-烯化学合成并研究潜在后代谢多粘菌素的生物活性
errChem. Commun.
IF0
err2025-12-04
err0
PREAI
errCatherine Smith; Andrew Siow; Renata Kowalczyk; Scott A. Ferguson; Matigan J. B. Smith; Gregory M. Cook; Veronika Sander; Alan J. Davidson; Margaret A. Brimble; Paul W. R. Harris
err分享
err收藏
Broad-Spectrum Peptidomimetic Inhibitors of Norovirus and Coronavirus 3C-like Proteases
errACS INFECTIOUS DISEASES
IF3.8
err2025-12-01
err0
PREAI
errBrimble, Margaret A.; Stubbing, Louise A.; Hermant, Yann O.; Yang, Sung-Hyun; Hubert, Jonathan G.; Pearl, Esperanza S.; Mcsweeney, Alice M.; Young, Vivienne L.; Campbell, Ashley C.; Opel-Reading, Helen K.; McKenzie-Goldsmith, Geena M.; Putha, Lohitha; Mortuza, Roman; Wang, Hong; Hurst, Brett L.; Julander, Justin; Harris, Lawrence D.; Krause, Kurt L.; Ward, Vernon K.
err分享
err收藏
Progress in peptide and protein therapeutics: Challenges and strategies肽和蛋白质治疗领域的进展：挑战与策略
errActa Pharmaceutica Sinica B
IF14.6
err2025-10-25
err0
errOAAI
errMengyang Liu; Darren Svirskis; Thomas Proft; Jacelyn Loh; Naibo Yin; Hao Li; Danhui Li; Yongzhi Zhou; Shuo Chen; Lizhuo Song; Guanyu Chen; Wei-Yue Lu; Zhiwen Zhang; Zhou Zhou; Lian Li; Yuan Huang; Craig Bunt; Guiju Sun; Paul W.R. Harris; Margaret A. Brimble; Jingyuan Wen
err分享
err收藏
Beyond the 2+2 Pharmacophore Electronic and Hydrophobic Effects Control the Activity of Cationic Amphiphilic Antimicrobial 2,5-Diketopiperazines除了2 2药效团之外，电子和疏水作用还控制阳离子两亲性抗菌剂2，5-二酮哌嗪的活性
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2025-10-01
err0
PREAI
errSiu, Christy; Siew, Tashia; Li, Freda F.; Mros, Sonya; Cleary, Caitlin S. B.; Ferguson, Scott A.; Cook, Gregory M.; Cahill, Patrick; Brimble, Margaret A.; Svenson, Johan; Rennison, David
err分享
err收藏
Spiroketal natural products isolated from traditional Chinese medicine: isolation; biological activity; biosynthesis; and synthesis从传统中药中分离的螺旋酮类天然产物：分离；生物活性；生物合成；以及合成
errNat. Prod. Rep.
IF10.6
err2025-07-21
err0
PREAI
errEilidh G. Young; Freda F. Li; Margaret A. Brimble
err分享
err收藏
Enhancing the Oral Bioavailability of Glutathione Using Innovative Analogue Approaches通过创新类似物方法提高谷胱甘肽的口服生物利用度
errPHARMACEUTICS
IF5.5
err2025-03-18
err0
errOAAI
errYin, Naibo; Harris, Paul W. R.; Liu, Mengyang; Sun, Jianguo; Chen, Guanyu; Wen, Jingyuan; Brimble, Margaret A.
err分享
err收藏
Development and pharmacological characterization of novel multi- calcitonin gene-related peptide and pituitary adenylate cyclase-activating peptide receptor antagonists新型多降钙素基因相关肽和垂体腺苷酸环化酶激活肽受体拮抗剂的开发和药理学表征
errHEADACHE
IF4
err2025-02-25
err0
errOAAI
errTasma, Zoe; Siow, Andrew; Harris, Paul W. R.; Brimble, Margaret A.; Hay, Debbie L.; Walker, Christopher S.
err分享
err收藏
Total Synthesis of (-)-Cordycicadin D and 3,4-trans-Cordycicadins A and B: Entry to the 3,4-trans-Fused Cordycicadin Framework
errANGEWANDTE CHEMIE-INTERNATIONAL EDITION
IF16.9
err2024-12-02
err0
errOAAI
errHunt, Liam R.; Grant, Phillip S.; Shimokura, Grace K.; Furkert, Daniel P.; Brimble, Margaret A.
err分享
err收藏
A Stable Dehydratase Complex Catalyzes the Formation of Dehydrated Amino Acids in a Class V Lanthipeptide
errACS CHEMICAL BIOLOGY
IF3.8
err2024-11-25
err0
PREAI
errRandall, George T.; Grant-Mackie, Emily S.; Chunkath, Shayhan; Williams, Elyse T.; Middleditch, Martin J.; Tao, Meifeng; Harris, Paul W. R.; Brimble, Margaret A.; Bashiri, Ghader
err分享
err收藏
Activity and cryo-EM structure of the polymerase domain of the human norovirus ProPol precursor
errJOURNAL OF VIROLOGY
IF3.8
err2024-11-19
err0
errOAAI
errMcSweeney, Alice M.; Eruera, Alice-Roza; McKenzie-Goldsmith, Geena M.; Bouwer, James C.; Brown, Simon H. J.; Stubbing, Louise A.; Hubert, Jonathan G.; Shrestha, Rinu; Sparrow, Kevin J.; Brimble, Margaret A.; Harris, Lawrence D.; Evans, Gary B.; Bostina, Mihnea; Krause, Kurt L.; Ward, Vernon K.
err分享
err收藏
Synthesis of the Spirocyclic Imine Fragment of Portimines Using a γ-Hydroxymethyl-α,β-butenolide Dienophile in a Diastereoselective Diels-Alder Reaction
errACS OMEGA
IF4.3
err2024-10-31
err0
errOAAI
errKuang, Ze; Ding, Xiao-Bo; Li, Freda F.; Brimble, Margaret A.
err分享
err收藏
Identification of Chemical Scaffolds That Inhibit the Mycobacterium tuberculosis Respiratory Complex Succinate Dehydrogenase抑制结核分枝杆菌呼吸复合琥珀酸脱氢酶的化学支架的鉴定
errACS INFECTIOUS DISEASES
IF3.8
err2024-09-13
err1
PREAI
errAdolph, Cara; Hards, Kiel; Williams, Zoe C.; Cheung, Chen-Yi; Keighley, Laura M.; Jowsey, William J.; Kyte, Matson; Inaoka, Daniel Ken; Kita, Kiyoshi; Mackenzie, Jared S.; Steyn, Adrie J. C.; Li, Zhengqiu; Yan, Ming; Tian, Guo-Bao; Zhang, Tianyu; Ding, Xiaobo; Furkert, Daniel P.; Brimble, Margaret A.; Hickey, Anthony J. R.; McNeil, Matthew B.; Cook, Gregory M.
err分享
err收藏
Allenamides as a Powerful Tool to Incorporate Diversity: Thia-Michael Lipidation of Semisynthetic Peptides and Access to β-Keto Amides
errANGEWANDTE CHEMIE-INTERNATIONAL EDITION
IF16.9
err2024-08-22
err1
errOAAI
errNa, Tae-Ung; Sander, Veronika; Davidson, Alan J.; Lin, Rolland; Hermant, Yann O.; Hardie Boys, Madeleine T.; Pletzer, Daniel; Campbell, Georgia; Ferguson, Scott A.; Cook, Gregory M.; Allison, Jane R.; Brimble, Margaret A.; Northrop, Brian H.; Cameron, Alan J.
err分享
err收藏
Use of a Cyclic α-Alkylidene-β-Diketone as a Cleavable Linker Strategy for Antibody-Drug Conjugates
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2024-08-15
err0
PREAI
errTong, Juliana T. W.; Sarwar, Makhdoom; Ahangarpour, Marzieh; Hume, Paul A.; Williams, Geoffrey M.; Brimble, Margaret A.; Kavianinia, Iman
err分享
err收藏
The Antimicrobial Peptide Capitellacin: Chemical Synthesis of Analogues to Probe the Role of Disulphide Bridges and Their Replacement with Vinyl Sulphides
errANTIBIOTICS-BASEL
IF4.6
err2024-07-02
err1
errOAAI
errShepperson, Oscar A.; Harris, Paul W. R.; Brimble, Margaret A.; Cameron, Alan J.
err分享
err收藏
Late-Stage Desulfurization Enables Rapid and Efficient Solid-Phase Synthesis of Cathepsin-Cleavable Linkers for Antibody-Drug Conjugates
errBIOCONJUGATE CHEMISTRY
IF3.9
err2024-06-14
err1
PREAI
errAhangarpour, Marzieh; Brimble, Margaret A.; Kavianinia, Iman
err分享
err收藏

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