未登录 Ugi-Type Reaction Enables Access to Fused Imidazole Derivatives for DNA-Encoded Library Technology Ugi型反应为DNA编码库技术提供杂环咪唑衍生物的合成途径 Guo, Hao; Li, Zitao; Wang, Gaonan; Zhang, Biyu; Wang, Mengxue; Liu, Lu; Satz, Alexander L.; Su, Wenji; Kuai, Letian; Zhang, Qi 分享 收藏
Optimization of a DNA encoded library derived autotaxin inhibitor hit to a potent in vivo LPA lowering quinazolinone compound with a non-zinc binding mode 基于DNA编码库筛选的自主生长因子抑制剂先导化合物的优化，获得了一种具有非锌结合模式的强效体内溶血磷脂酸降低的喹唑啉酮类化合物。 Martin, Rainer E.; Satz, Alexander L.; Kuratli, Christoph; Hunziker, Daniel; Mattei, Patrizio; Hert, Jerome; Ullmer, Christoph; Rudolph, Markus G.; Alker, Andre M.; Hochstrasser, Remo; Marx, Andreas; Binder, Martin; Muller, Stephan 分享 收藏
DNA-Compatible Huisgen [3+2] Cycloaddition of In Situ Formed Nitrile Oxides with Alkenes or Alkynes to Synthesize Isoxazolines or Isoxazoles Wang, Gaonan; Zhang, Xiaona; Zhu, Hui; Shi, Xiaodong; Wen, Zhuo; Zhang, Qi; Satz, Alexander L.; Su, Wenji; Kuai, Letian; Dai, Dongcheng 分享 收藏
Optimization of a Novel DEL Hit That Binds in the Cbl-b SH2 Domain and Blocks Substrate Binding Liang, Jun; Lambrecht, Michael J.; Arenzana, Teresita L.; Aubert-Nicol, Samuel; Bao, Linda; Broccatelli, Fabio; Cai, Jianping; Eidenschenk, Celine; Everett, Christine; Garner, Thomas; Gruber, Felix; Haghshenas, Pouyan; Huestis, Malcolm P.; Hsu, Peter L.; Kou, Ponien; Jakalian, Araz; Larouche-Gauthier, Robin; Leclerc, Jean-Philippe; Leung, Dennis H.; Martin, Aaron; Murray, Jeremy; Prangley, Madeleine; Rutz, Sascha; Kakiuchi-Kiyota, Satoko; Satz, Alexander Lee; Skelton, Nicholas J.; Steffek, Micah; Stoffler, Daniel; Sudhamsu, Jawahar; Tan, Sophia; Wang, Jian; Wang, Shouliang; Wang, Qiuyue; Wendorff, Timothy J.; Wichert, Moreno; Yadav, Arun; Yu, Christine; Wang, Xiaojing 分享 收藏
DNA-Compatible Cyclization Reaction to Access 1,3,4-Oxadiazoles and 1,2,4-Triazoles Wang, Gaonan; Tan, Yu; Zou, Hanzhi; Sui, Xihang; Wang, Zhanlong; Satz, Alexander L.; Kuai, Letian; Su, Wenji; Zhang, Qi 分享 收藏
DNA-Encoded Macrocyclic Peptide Libraries Enable the Discovery of a Neutral MDM2-p53 Inhibitor Silvestri, Anthony P.; Zhang, Qi; Ping, Yan; Muir, Erik W.; Zhao, Jingsi; Chakka, Sai Kumar; Wang, Gaonan; Bray, Walter M.; Chen, Wenhua; Fribourgh, Jennifer L.; Tripathi, Sarvind; He, Yunyun; Rubin, Seth M.; Satz, Alexander L.; Pye, Cameron R.; Kuai, Letian; Su, Wenji; Schwochert, Joshua A. 分享 收藏
Assessment of AI-Based Protein Structure Prediction for the NLRP3 Target Yin, Jian; Lei, Junkun; Yu, Jialin; Cui, Weiren; Satz, Alexander L.; Zhou, Yifan; Feng, Hua; Deng, Jason; Su, Wenji; Kuai, Letian 分享 收藏
Discovery of a Highly Selective BET BD2 Inhibitor from a DNA-Encoded Library Technology Screening Hit Rianjongdee, Francesco; Atkinson, Stephen J.; Chung, Chun-Wa; Grandi, Paola; Gray, James R. J.; Kaushansky, Laura J.; Medeiros, Patricia; Messenger, Cassie; Phillipou, Alex; Preston, Alex; Prinjha, Rab K.; Rioja, Inmaculada; Satz, Alexander L.; Taylor, Simon; Wall, Ian D.; Watson, Robert J.; Yao, Gang; Demont, Emmanuel H. 分享 收藏
Triaging of DNA-Encoded Library Selection Results by High-Throughput Resynthesis of DNA-Conjugate and Affinity Selection Mass Spectrometry Su, Wenji; Ge, Rui; Ding, Duanchen; Chen, Wenhua; Wang, Wenqing; Yan, Hao; Wang, Weikun; Yuan, Youlang; Liu, Huan; Zhang, Meng; Zhang, Jiyuan; Shu, Qisheng; Satz, Alexander L.; Kuai, Letian 分享 收藏
Synthesis of 1,2-Amino Alcohols by Photoredox-Mediated Decarboxylative Coupling of α-Amino Acids and DNA-Conjugated Carbonyls Wen, Huanan; Ge, Rui; Qu, Yi; Sun, Jialin; Shi, Xiaodong; Cui, Weiren; Yan, Hao; Zhang, Qi; An, Yulong; Su, Wenji; Yang, Hongfang; Kuai, Letian; Satz, Alexander L.; Peng, Xuanjia 分享 收藏
DNA-Compatible Copper-Catalyzed Oxidative Amidation of Aldehydes with Non-Nucleophilic Arylamines Li, Ke; Qu, Yi; An, Yulong; Breinlinger, Eric; Webster, Matthew P.; Wen, Huanan; Ding, Duanchen; Zhao, Meng; Shi, Xiaodong; Wang, Jiangong; Su, Wenji; Cui, Weiren; Satz, Alexander L.; Yang, Hongfang; Kuai, Letian; Little, Andrew; Peng, Xuanjia 分享 收藏
Copper-Mediated DNA-Compatible One-Pot Click Reactions of Alkynes with Aryl Borates and TMS-N3 Qu, Yi; Wen, Huanan; Ge, Rui; Xu, Yanfen; Gao, Hong; Shi, Xiaodong; Wang, Jiangong; Cui, Weiren; Su, Wenji; Yang, Hongfang; Kuai, Letian; Satz, Alexander L.; Peng, Xuanjia 分享 收藏
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DNA-Encoded Library-Derived DDR1 Inhibitor Prevents Fibrosis and Renal Function Loss in a Genetic Mouse Model of Alport Syndrome Richter, Hans; Satz, Alexander L.; Bedoucha, Marc; Buettelmann, Bernd; Petersen, Ann C.; Harmeier, Anja; Hermosillo, Ricardo; Hochstrasser, Remo; Burger, Dominique; Gsell, Bernard; Gasser, Rodolfo; Huber, Sylwia; Hug, Melanie N.; Kocer, Buelent; Kuhn, Bernd; Ritter, Martin; Rudolph, Markus G.; Weibel, Franziska; Molina-David, Judith; Kim, Jin-Ju; Santos, Javier Varona; Stihle, Martine; Georges, Guy J.; Bonfil, R. Daniel; Fridman, Rafael; Uhles, Sabine; Moll, Solange; Faul, Christian; Fornoni, Alessia; Prunotto, Marco 分享 收藏
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DNA Compatible Multistep Synthesis and Applications to DNA Encoded Libraries (vol 26, pg 1623, 2015) Satz, Alexander Lee; Cai, Jianping; Chen, Yi; Goodnow, Robert; Gruber, Felix; Kowalczyk, Agnieszka; Petersen, Ann; Naderi-Oboodi, Goli; Orzechowski, Lucja; Strebel, Quentin 分享 收藏
Discovery and Characterization of a Class of Pyrazole Inhibitors of Bacterial Undecaprenyl Pyrophosphate Synthase Concha, Nestor; Huang, Jianzhong; Bai, Xiaopeng; Benowitz, Andrew; Brady, Pat; Grady, LaShadric C.; Kryn, Luz Helena; Holmes, David; Ingraham, Karen; Jin, Qi; Kaushansky, Laura Pothier; McCloskey, Lynn; Messer, Jeffrey A.; O'Keefe, Heather; Patel, Amish; Satz, Alexander L.; Sinnamon, Robert H.; Schneck, Jessica; Skinner, Steve R.; Summerfield, Jennifer; Taylor, Amy; Taylor, J. David; Evindar, Ghotas; Stavenger, Robert A. 分享 收藏
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Discovery, SAR, and X-ray Binding Mode Study of BCATm Inhibitors from a Novel DNA-Encoded Library Deng, Hongfeng; Zhou, Jingye; Sundersingh, Flora S.; Summerfield, Jennifer; Somers, Don; Messer, Jeffrey A.; Satz, Alexander L.; Ancellin, Nicolas; Arico-Muendel, Christopher C.; Bedard, Katie L. (Sargent); Beljean, Arthur; Belyanskaya, Svetlana L.; Bingham, Ryan; Smith, Sarah E.; Boursier, Eric; Carter, Paul; Centrella, Paolo A.; Clark, Matthew A.; Chung, Chun-wa; Davie, Christopher P.; Delorey, Jennifer L.; Ding, Yun; Franklin, G. Joseph; Grady, LaShadric C.; Herry, Kenny; Hobbs, Clare; Kollmann, Christopher S.; Morgan, Barry A.; Kaushansky, Laura J. (Pothier); Zhou, Quan 分享 收藏
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