Yilei Guo

China Pharmaceutical University

H指数:8

被引数:187

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Aryl hydrocarbon receptor deficiency triggers the activation of γδT17 cells to exacerbate autoimmune inflammation

芳基烃受体缺陷触发γδT17细胞的活化以加剧自身免疫性炎症

Science Advances

IF12.5

2026-07-030

Estrogen receptor β deficiency increases the susceptibility to ulcerative colitis by inducing mitochondrial fission and consequently accelerating senescence of colonic epithelial cells

雌激素受体β缺陷通过诱导线粒体分裂并进而加速结肠上皮细胞衰老，增加了对溃疡性结肠炎的易感性。

Redox Biology

IF11.9

2025-11-050

OAAI

Norisoboldine restrains γδT17 cell activation and consequently alleviates psoriasis-like dermatitis in mice by selectively down-regulating glutaminolysis to decrease the level of α-ketoglutarate

诺异波巴 Staple 抑制 γδT17 细胞活化，并通过选择性下调谷氨酰胺分解以降低 α-酮戊二酸水平，从而在 mice 中缓解银屑病样皮炎。

Journal of Advanced Research

IF13

2025-10-240

OAAI

Bergenin inhibits γδT17 cell activation to alleviate ulcerative colitis by down-regulating fatty acid oxidation via targeting miR-124–3p

Bergenin通过靶向miR-124–3p下调脂肪酸氧化，抑制γδT17细胞活化以缓解溃疡性结肠炎。

Phytomedicine

IF8.3

2025-10-030

PRE

7-Ketodeoxycholic Acid Promotes Colonic Mucosal Healing by Inducing Calcium Release from Endoplasmic Reticulum via the TGR5-IP3R Pathway

7-Ketodeoxycholic Acid 通过 TGR5-IP3R 通路诱导内质网钙释放促进结肠黏膜愈合

Advanced Science

IF14.1

2025-09-150

OAAI

α7nAChR activation promotes the generation of Treg cells by enhancing the dephosphorylation of Foxo1 via the IP3R/Ca2+/calcineurin pathway

α7nAChR的激活通过IP3R/Ca2+/calcineurin通路增强Foxo1的去磷酸化，从而促进Treg细胞的生成。

Biochemical Pharmacology

IF5.6

2025-08-290

PRE

Intestinal Butyrate Ameliorates Rheumatoid Arthritis Through Promoting the Expression of Cortistatin in Ileum via HDAC3-Vitamin D Receptor Pathway

肠道丁酸盐通过促进回肠中通过HDAC3-维生素D受体通路促进皮质素的表达来改善类风湿性关节炎。

IMMUNOLOGY

IF5

2025-04-300

PRE

Facilitation of mucosal healing by estrogen receptor b in ulcerative colitis through suppression of branched-chain amino acid transport and subsequent triggering of autophagy in colonic epithelial cells

雌激素受体β通过抑制支链氨基酸转运和随后的触发结肠上皮细胞自噬，促进溃疡性结肠炎的黏膜愈合。

ACTA PHARMACEUTICA SINICA B

IF14.6

2025-01-010

OAAI

Bergenin attenuates triptolide-caused premature ovarian failure in mice based on the antioxidant activity

REPRODUCTIVE TOXICOLOGY

IF2.8

2024-06-015

PRE

Estrogen receptor β activation alleviates inflammatory bowel disease by suppressing NLRP3-dependent IL-1β production in macrophages via downregulation of intracellular calcium level

雌激素受体β激活通过下调巨噬细胞内钙离子水平，抑制NLRP3依赖的IL-1β产生，从而缓解炎症性肠病。

JOURNAL OF ADVANCED RESEARCH

IF13

2024-06-018

OAAI

Arctigenin promotes mucosal healing in ulcerative colitis through facilitating focal adhesion assembly and colonic epithelial cell migration via targeting focal adhesion kinase

INTERNATIONAL IMMUNOPHARMACOLOGY

IF4.7

2024-02-012

PRE

Mume Fructus (Prunus mume Sieb. et Zucc.) extract accelerates colonic mucosal healing of mice with colitis induced by dextran sulfate sodium through potentiation of cPLA2-mediated lysophosphatidylcholine synthesis

PHYTOMEDICINE

IF8.3

2023-10-012

PRE

Mitochondrial fusion induced by transforming growth factor-β1 serves as a switch that governs the metabolic reprogramming during differentiation of regulatory T cells

REDOX BIOLOGY

IF11.9

2023-06-0112

Cholinergic dysfunction-induced insufficient activation of alpha7 nicotinic acetylcholine receptor drives the development of rheumatoid arthritis through promoting protein citrullination via the SP3/PAD4 pathway

ACTA PHARMACEUTICA SINICA B

IF14.6

2023-04-015

OAAI

The neuropeptide cortistatin attenuates Th17 cell response through inhibition of glycolysis via GHSR1

INTERNATIONAL IMMUNOPHARMACOLOGY

IF4.7

2022-07-012

PRE

Tetrandrine attenuates intestinal epithelial barrier defects caused by colitis through promoting the expression of Occludin via the AhR-miR-429 pathway

粉防己碱通过AhR-miR-429途径促进Occludin的表达减轻结肠炎引起的肠上皮屏障缺陷

FASEB JOURNAL

IF4.2

2021-04-0322

PRE

Yilei Guo

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