Changjie Wu

southern medical university - china

H指数:16

被引数:980

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Targeting miR-4653-3p/SLC25A51/SIRT3 axis to induce synthetic lethality in ARID1A-deficient colorectal cancer via blockade of DNA repair

靶向miR-4653-3p/SLC25A51/SIRT3轴阻断DNA修复诱导ARID1A-deficient结直肠癌合成致死率

Journal of Translational Medicine

IF7.5

2026-02-040

OAAI

ARID1A deficiency activates OSM-STAT3 axis in endometrial cancer, creating vulnerability to JAK/STAT3 inhibition

ARID1A缺陷激活子宫内膜癌中的OSM-STAT3轴，使其对JAK/STAT3抑制产生易感性

International Journal of Biological Sciences

IF10

2026-01-010

PRE

FUT3 mediated GRP78 fucosylation promotes colorectal cancer survival and proliferation under glucose restriction via PERK/ATF4/STC2 axis

FUT3介导的GRP78岩藻糖基化通过PERK/ATF4/STC2轴促进葡萄糖限制条件下结直肠癌的生存和增殖

npj Precision Oncology

IF8

2025-12-140

OAAI

Disulfiram activates autophagy via proteasome inhibition and c-Fos/beclin-1 upregulation, synergizing with chloroquine

二硫代氨基甲酸通过蛋白酶体抑制和c-Fos/beclin-1上调激活自噬，并与氯喹协同作用

Cell Death Discovery

IF7

2025-12-120

OAAI

MAP4 phosphorylation induced by ARID1A loss sensitizes colorectal cancer cells to EMP

ARID1A缺失诱导的MAP4磷酸化使结直肠癌细胞对EMP敏感

Cell Death & Disease

IF9.6

2025-12-080

ARID1A loss enhances sensitivity to c-MET inhibition by dual targeting of GPX4 and iron homeostasis, inducing ferroptosis

ARID1A缺失通过双重靶向GPX4和铁稳态增强对c-MET抑制的敏感性，诱导铁死亡。

CELL DEATH AND DIFFERENTIATION

IF15.4

2025-05-140

ARID1A loss sensitizes colorectal cancer cells to floxuridine

ARID1A缺失使结直肠癌细胞对氟尿苷敏感

NEOPLASIA

IF7.7

2024-12-010

PRE

Deficiency of SDHC promotes metastasis by reprogramming fatty acid metabolism in colorectal cancer

SDHC缺乏通过重编程脂肪酸代谢促进结直肠癌转移

JOURNAL OF TRANSLATIONAL MEDICINE

IF7.5

2024-06-061

OAAI

Therapeutic targeting of ARID1A-deficient cancer cells with RITA (Reactivating p53 and inducing tumor apoptosis)

CELL DEATH & DISEASE

IF9.6

2024-05-294

OAAI

Adipose-derived stem cells promote glycolysis and peritoneal metastasis via TGF-β1/SMAD3/ANGPTL4 axis in colorectal cancer

脂肪干细胞通过TGF-β1/SMAD3/ANGPTL4轴促进结直肠癌糖酵解和腹膜转移

CELLULAR AND MOLECULAR LIFE SCIENCES

IF6.2

2024-04-217

OAAI

LIMK1 m6A-RNA methylation recognized by YTHDC2 induces 5-FU chemoresistance in colorectal cancer via endoplasmic reticulum stress and stress granule formation

CANCER LETTERS

IF10.1

2023-11-0112

PRE

METTL14-dependent maturation of pri-miR-17 regulates mitochondrial homeostasis and induces chemoresistance in colorectal cancer

pri-miR-17的METTL14-dependent成熟调节线粒体稳态并诱导结直肠癌的化学抗性

CELL DEATH & DISEASE

IF9.6

2023-02-2127

OAAI

A pan-cancer analysis of thioredoxin-interacting protein as an immunological and prognostic biomarker

硫氧还蛋白相互作用蛋白作为免疫学和预后生物标志物的泛癌症分析

CANCER CELL INTERNATIONAL

IF6

2022-07-177

OAAI

Tumor-suppressive function of EZH2 is through inhibiting glutaminase

CELL DEATH & DISEASE

IF9.6

2021-10-209

OAAI

Synthetic lethality of RB1 and aurora A is driven by stathmin-mediated disruption of microtubule dynamics

NATURE COMMUNICATIONS

IF15.7

2020-10-0939

OAAI

Cancer-associated fibroblasts-derived exosomal miR-17-5p promotes colorectal cancer aggressive phenotype by initiating a RUNX3/MYC/TGF-β1 positive feedback loop

癌症相关成纤维细胞来源的外泌体miR-17-5p通过启动RUNX3/MYC/TGF-β1正反馈回路促进结直肠癌侵袭性表型

CANCER LETTERS

IF10.1

2020-10-0173

PREAI

CTCF promotes colorectal cancer cell proliferation and chemotherapy resistance to 5-FU via the P53-Hedgehog axis

AGING-US

IF3.9

2020-07-2029

OAAI

Class I histone deacetylase inhibition is synthetic lethal with BRCA1 deficiency in breast cancer cells

ACTA PHARMACEUTICA SINICA B

IF14.6

2020-04-0126

OAAI

PTEN deficiency confers colorectal cancer cell resistance to dual inhibitors of FLT3 and aurora kinase A

CANCER LETTERS

IF10.1

2018-11-0114

PREAI

Targeting AURKA-CDC25C axis to induce synthetic lethality in ARID1A-deficient colorectal cancer cells

NATURE COMMUNICATIONS

IF15.7

2018-08-1099

OAAI

Changjie Wu

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