Xintong Zhang

Peking Union Medical College and Chinese Academy of Medical Sciences

H指数:14

被引数:787

个人简介

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Construction of novel enone-aloperine derivatives and their distinct mechanistic insights into PD-L1 suppression in a reversible covalent manner

新型烯酮-阿洛平衍生物的构建及其通过可逆共价方式抑制PD-L1的差异性机制洞察

Acta Pharmaceutica Sinica B

IF14.6

2026-07-240

Emerging insights into lineage plasticity in pancreatic cancer initiation, progression, and therapy resistance

新兴的对胰腺癌起始、进展和疗法抵抗中线系塑性的认识

Developmental Cell

IF8.7

2025-09-220

OAAI

High-cis astaxanthin nano lipid carrier: Preparation and bioavailability analysis

高顺式虾青素纳米脂质载体：制备与生物利用度分析

FOOD BIOSCIENCE

IF5.9

2025-06-010

PRE

Risk factors for failing endotracheal extubation in neurocritical patients: a retrospective cohort study

神经危重症患者拔管失败的风险因素：一项回顾性队列研究

FRONTIERS IN NEUROLOGY

IF2.8

2025-03-260

Elimination of antimicrobial resistance in reclaimed water by UV/NaClO: Simultaneous removal of ampicillin, blaNDM-1-carrying super-resistant bacteria and blaNDM-1 genes

JOURNAL OF WATER PROCESS ENGINEERING

IF6.7

2025-03-010

PRE

Engineering and Development of a Novel Bispecific Antibody Targeting both TL1A and α4β7 for the Treatment of IBD

JOURNAL OF CROHNS & COLITIS

IF8.7

2025-01-220

PRE

P1114 Engineering and Development of a Novel Bispecific Antibody Targeting IL-23 and TL1A

JOURNAL OF CROHNS & COLITIS

IF8.7

2025-01-220

PRE

Novel berberine derivatives as adjuvants in the battle against Acinetobacter baumannii : A promising strategy for combating multi-drug resistance

CHINESE CHEMICAL LETTERS

IF8.9

2024-10-011

PRE

Electrical Conductivity Characteristic of Polyimide under Long-Term Combined Electron Irradiation and Thermal Cycle in Vacuum

ACS APPLIED MATERIALS & INTERFACES

IF8.2

2024-08-150

PRE

Macrophage-hitchhiking interleukin-10 plasmid DNA delivery system modulates rheumatoid arthritis microenvironment via the re-polarization of macrophages

巨噬细胞搭便车interleukin-10质粒DNA递送系统通过巨噬细胞的重新极化调节类风湿关节炎微环境

NANO TODAY

IF10.9

2024-02-012

PRE

Versatile flexible micelles integrating mucosal penetration and intestinal targeting for effectively oral delivery of paclitaxel

ACTA PHARMACEUTICA SINICA B

IF14.6

2023-08-017

OAAI

An EGCG-mediated self-assembled micellar complex acts as a bioactive drug carrier

FOOD CHEMISTRY

IF9.8

2023-08-011

PRE

Research Advances in Nucleic Acid Delivery System for Rheumatoid Arthritis Therapy

PHARMACEUTICS

IF5.5

2023-04-133

OAAI

N-acetyl-L-cysteine alleviated the oxidative stress-induced inflammation and necroptosis caused by excessive NiCl2 in primary spleen lymphocytes

FRONTIERS IN IMMUNOLOGY

IF5.9

2023-04-062

OAAI

Palmatine Derivatives as Potential Antiplatelet Aggregation Agentsvia Protein Kinase G/Vasodilator-Stimulated Phosphoprotein andPhosphatidylinositol 3-Kinase/Akt Phosphorylation

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2022-05-1311

PRE

Capture and Identification of Dual Specificity Mitogen-Activated Protein Kinase Kinase 7 as a Direct Proteomic Target of Berberine to Affect the c-JunN-Terminal Kinase Pathway

CCS CHEMISTRY

IF9.2

2022-05-0112

Clofazimine derivatives as potent broad-spectrum antiviral agents with dual-target mechanism

氯法齐明衍生物作为具有双重靶向机制的有效广谱抗病毒药物

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2022-04-019

OAAI

Sequential Delivery of Quercetin and Paclitaxel for the Fibrotic Tumor Microenvironment Remodeling and Chemotherapy Potentiation via a Dual-Targeting Hybrid Micelle-in-Liposome System

槲皮素和紫杉醇通过双靶向混合胶束脂质体系统顺序递送对纤维化肿瘤微环境重塑和化疗增强作用

ACS APPLIED MATERIALS & INTERFACES

IF8.2

2022-02-1728

PRE

Effective oral delivery of Exenatide-Zn2+complex through distal ileum-targeted double layers nanocarriers modified with deoxycholic acid and glycocholic acid in diabetes therapy

BIOMATERIALS

IF12.9

2021-08-0121

PREAI

The influence of the gut microbiota on the bioavailability of oral drugs

肠道菌群对口服药物生物利用度的影响

ACTA PHARMACEUTICA SINICA B

IF14.6

2021-07-01123

OAAI

Xintong Zhang

个人简介

教育背景

工作经历

荣誉奖项

研究方向