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SGLT2 inhibition protects kidney function by SAM-dependent epigenetic repression of inflammatory genes under metabolic stress SGLT2抑制剂通过SAM依赖的表观遗传抑制代谢应激下的炎症基因来保护肾功能。 Maekawa, Hiroshi; Zhou, Yalu; Aoi, Yuki; Fain, Margaret E.; Kaminski, Dorian S.; Kong, Hyewon; Sebo, Zachary L.; Chakrabarty, Ram P.; Howard, Benjamin C.; Andersen, Grant; Marcheva, Biliana; Gao, Peng; Kapitsinou, Pinelopi; Bass, Joseph; Shilatifard, Ali; Chandel, Navdeep S.; Quaggin, Susan E. 分享 收藏
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Control of circadian muscle glucose metabolism through the BMAL1-HIF axis in obesity 通过BMAL1-HIF轴对肥胖症中肌肉葡萄糖代谢的节律性控制 Chaikin, Claire A.; Thakkar, Abhishek, V; Steffeck, Adam W. T.; Pfrender, Eric M.; Hung, Kaitlyn; Zhu, Pei; Waldeck, Nathan J.; Nozawa, Rino; Song, Weimin; Futtner, Christopher R.; Quattrocelli, Mattia; Bass, Joseph; Ben-Sahra, Issam; Peek, Clara B. 分享 收藏
Misaligned feeding uncouples daily rhythms within brown adipose tissue and between peripheral clocks 未对齐的喂养会断开棕色脂肪组织内和周围时钟之间的每日节律 Acosta-Rodriguez, Victoria A.; Rijo-Ferreira, Filipa; van Rosmalen, Laura; Izumo, Mariko; Park, Noheon; Joseph, Chryshanthi; Hepler, Chelsea; Thorne, Anneke K.; Stubblefield, Jeremy; Bass, Joseph; Green, Carla B.; Takahashi, Joseph S. 分享 收藏
Mitochondria regulate proliferation in adult cardiac myocytes Waypa, Gregory B.; Smith, Kimberly A.; Mungai, Paul T.; Dudley, Vincent J.; Helmin, Kathryn A.; Singer, Benjamin D.; Peek, Clara Bien; Bass, Joseph; Nelson, Lauren; Shah, Sanjiv J.; Ofman, Gaston; Wasserstrom, J. Andrew; Muller, William A.; V. Misharin, Alexander; Budinger, G. R. Scott; Abdala-Valencia, Hiam; Chandel, Navdeep S.; Dokic, Danijela; Bartom, Elizabeth; Zhang, Shuang; Tatekoshi, Yuki; Mahmoodzadeh, Amir; Ardehali, Hossein; Thorp, Edward B.; Schumacker, Paul T. 分享 收藏
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Repression of latent NF-κB enhancers by PDX1 regulates β cell functional heterogeneity Weidemann, Benjamin J.; Marcheva, Biliana; Kobayashi, Mikoto; Omura, Chiaki; Newman, Marsha, V; Kobayashi, Yumiko; Waldeck, Nathan J.; Perelis, Mark; Lantier, Louise; McGuinness, Owen P.; Ramsey, Kathryn Moynihan; Stein, Roland W.; Bass, Joseph 分享 收藏
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When a calorie is not just a calorie: Diet quality and timing as mediators of metabolism and healthy aging Mihaylova, Maria M.; Chaix, Amandine; Delibegovic, Mirela; Ramsey, Jon J.; Bass, Joseph; Melkani, Girish; Singh, Rajat; Chen, Zheng; Ja, William W.; Shirasu-Hiza, Michele; Latimer, Mary N.; Mattison, Julie A.; Thalacker-Mercer, Anna E.; Dixit, Vishwa Deep; Panda, Satchidananda; Lamming, Dudley W. 分享 收藏
Gastric bypass alters diurnal feeding behavior and reprograms the hepatic clock to regulate endogenous glucose flux Ye, Yuanchao; Abu El Haija, Marwa; Obeid, Reine; Herz, Hussein; Tian, Liping; Linden, Benjamin; Chu, Yi; Guo, Deng Fu; Levine, Daniel C. .; Cedernaes, Jonathan; Rahmouni, Kamal; Bass, Joseph; Mokadem, Mohamad 分享 收藏
Leptin Deficiency and Beta-Cell Dysfunction Underlie Type 2 Diabetes in Compound Akt Knockout Mice Chen, William S.; Peng, Xiao-Ding; Wang, Yong; Xu, Pei-Zhang; Chen, Mei-Ling; Luo, Yongmei; Jeon, Sang-Min; Coleman, Kevin; Haschek, Wanda M.; Bass, Joseph; Philipson, Louis H.; Hay, Nissim 分享 收藏
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mTOR regulation of metabolism limits LPS-induced monocyte inflammatory and procoagulant responses mTOR调节代谢限制LPS诱导的单核细胞炎症和促凝血反应 Lund, Nina C.; Kayode, Yetunde; McReynolds, Melanie R.; Clemmer, Deanna C.; Hudson, Hannah; Clerc, Isabelle; Hong, Hee-Kyung; Brenchley, Jason M.; Bass, Joseph; D'Aquila, Richard T.; Taylor, Harry E. 分享 收藏
Impact of circadian time of dosing on cardiomyocyte-autonomous effects of glucocorticoids Wintzinger, Michelle; Panta, Manoj; Miz, Karen; Prabakaran, Ashok D.; Durumutla, Hima Bindu; Sargent, Michelle; Peek, Clara Bien; Bass, Joseph; Molkentin, Jeffery D.; Quattrocelli, Mattia 分享 收藏
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P2Y1 purinergic receptor identified as a diabetes target in a small-molecule screen to reverse circadian β-cell failure Marcheva, Biliana; Weidemann, Benjamin J.; Taguchi, Akihiko; Perelis, Mark; Ramsey, Kathryn Moynihan; Newman, Marsha, V; Kobayashi, Yumiko; Omura, Chiaki; Fox, Jocelyn E. Manning; Lin, Haopeng; Macdonald, Patrick E.; Bass, Joseph 分享 收藏
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NADH inhibition of SIRT1 links energy state to transcription during time-restricted feeding NADH抑制SIRT1在时间限制的喂养过程中将能量状态与转录联系起来 Levine, Daniel C.; Kuo, Hsin-Yu; Hong, Hee-Kyung; Cedernaes, Jonathan; Hepler, Chelsea; Wright, Alexandra G.; Sommars, Meredith A.; Kobayashi, Yumiko; Marcheva, Biliana; Gao, Peng; Ilkayeva, Olga R.; Omura, Chiaki; Ramsey, Kathryn M.; Newgard, Christopher B.; Barish, Grant D.; Peek, Clara Bien; Chandel, Navdeep S.; Mrksich, Milan; Bass, Joseph 分享 收藏
Understanding Circadian Mechanisms of Sudden Cardiac Death: A Report From the National Heart, Lung, and Blood Institute Workshop, Part 2: Population and Clinical Considerations Delisle, Brian P.; George, Alfred L.; Nerbonne, Jeanne M.; Bass, Joseph T.; Ripplinger, Crystal M.; Jain, Mukesh K.; Hermanstyne, Tracey O.; Young, Martin E.; Kannankeril, Prince J.; Duffy, Jeanne F.; Goldhaber, Joshua I.; Hall, Martica H.; Somers, Virend K.; Smolensky, Michael H.; Garnett, Christine E.; Anafi, Ron C.; Scheer, Frank A. J. L.; Shivkumar, Kalyanam; Shea, Steven A.; Balijepalli, Ravi C. 分享 收藏
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