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任思强 (Siqiang Ren)

southern medical university高层次引进人才

H指数:17

被引数:945

个人简介

南方医科大学2020年高层次引进人才。2013年取得南京医科大学博士学位，2014年至2020年先后在美国纪念斯隆凯特琳癌症中心和罗格斯大学医学院开展博士后研究。课题组主要借助病毒介导的神经环路示踪、离体多通道全细胞膜片钳、在体钙成像和光遗传学等技术，研究大脑神经环路网络的结构以及生理病理功能。

教育背景

2013.12
南京医科大学博士学位

工作经历

2020.01 – 至今
南方医科大学
高层次引进人才
2014.01 – 至今
美国纪念斯隆凯特琳癌症中心
博士后
2020.12
罗格斯大学医学院
博士后

荣誉奖项

江苏省优秀博士毕业论文（2014）｜江苏省
干细胞计划学者奖学金（2015）｜纪念斯隆凯特琳癌症中心、洛克菲勒大学和康奈尔大学医学院三医研究所

Newborn neurons compete with neuronal ensembles to moderate behavioral responses to stress

新生神经元与神经元集合竞争以调节对压力的行为反应

IF6.9

2026-08-200

OAAI

Effects of FGF4/HIF-1α axis-mediated neuronal glycolysis on neuropathic pain

FGF4/HIF-1α轴介导的神经元糖酵解对神经病理性疼痛的影响

The Journal of Headache and Pain

IF7.9

2026-04-200

OAAI

The axon initial segment-associated microglia regulate neuronal activity and visual perception

轴突初始节段相关的小胶质细胞调节神经元活动和视觉感知

IF25.9

2026-01-280

OAAI

Microglial TREM2 deficiency causes E/I imbalance and triggers ASD-like behaviors by altering potassium channel Kv1.3 activation

小胶质细胞TREM2缺陷通过改变钾离子通道Kv1.3的激活，导致兴奋/抑制失衡并引发类似自闭症的行为。

Neurobiology of Disease

IF5.6

2025-11-080

OAAI

Swimming exercise alleviates peripheral neuropathic pain by downregulating FTO and promoting m6A methylation of miR-183

游泳运动通过下调FTO并促进miR-183的m6A甲基化来缓解外周神经病理性疼痛

The Journal of Headache and Pain

IF7.9

2025-10-310

OAAI

Gain of bipolar disorder-related lncRNA AP1AR-DT in mice induces depressive and anxiety-like behaviors by reducing Negr1-mediated excitatory synaptic transmission

IF8.3

2024-11-180

OAAI

The prevalence and factors associated with neck and low back pain in patients with stroke: insights from the CHARLS

中风患者颈部和腰背痛的患病率和相关因素: 来自CHARLS的见解

BMC PUBLIC HEALTH

IF3.6

2024-08-300

OAAI

Hippocampal excitation-inhibition balance underlies the 5-HT2C receptor in modulating depressive behaviours

IF11.7

2024-05-031

PRE

A kidney-brain neural circuit drives progressive kidney damage and heart failure

肾-脑神经回路驱动进行性肾损伤和心力衰竭

Signal Transduction and Targeted Therapy

IF52.7

2023-05-120

OAAI

Electroacupuncture alleviated depression-like behaviors in ventromedial prefrontal cortex of chronic unpredictable mild stress-induced rats: Increasing synaptic transmission and phosphorylating dopamine transporter

CNS NEUROSCIENCE & THERAPEUTICS

IF5

2023-04-0111

OA

Functional investigation of SLC1A2 variants associated with epilepsy

CELL DEATH & DISEASE

IF9.6

2022-12-217

OAAI

TNF-α-mediated reduction in inhibitory neurotransmission precedes sporadic Alzheimer's disease pathology in young Trem2R47H rats

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2021-01-0124

OAAI

Resveratrol mediates mechanical allodynia through modulating inflammatory response via the TREM2-autophagy axis in SNI rat model

白藜芦醇通过TREM2-autophagy轴调节炎症反应介导SNI大鼠机械性异常性疼痛

JOURNAL OF NEUROINFLAMMATION

IF10.1

2020-10-2154

OAAI

Microglia TREM2R47H Alzheimer-linked variant enhances excitatory transmission and reduces LTP via increased TNF-α levels

IF0

2020-06-2432

OAAI

Precise Long-Range Microcircuit-to-Microcircuit Communication Connects the Frontal and Sensory Cortices in the Mammalian Brain

精确的远程微电路到微电路通信连接哺乳动物大脑中的额叶和感觉皮层

IF15

2019-10-0118

OAAI

TBR2 coordinates neurogenesis expansion and precise microcircuit organization via Protocadherin 19 in the mammalian cortex

NATURE COMMUNICATIONS

IF15.7

2019-09-0255

OAAI

Amyloid β causes excitation/inhibition imbalance through dopamine receptor 1-dependent disruption of fast-spiking GABAergic input in anterior cingulate cortex

SCIENTIFIC REPORTS

IF3.9

2018-01-1052

OAAI

Distinct Roles of PKCι/λ and PKMζ in the Initiation and Maintenance of Hippocampal Long-Term Potentiation and Memory

IF6.9

2016-08-0143

OAAI

Vascular Influence on Ventral Telencephalic Progenitors and Neocortical Interneuron Production

DEVELOPMENTAL CELL

IF8.7

2016-03-0167

OAAI

PKCλ is critical in AMPA receptor phosphorylation and synaptic incorporation during LTP

IF8.3

2013-03-19109

OA

研究方向

大脑皮层单个神经元起始的神经网络结构和功能TREM2及小胶质细胞的生理病理功能杏仁核内微环路的结构和功能神经环路和网络病毒介导的环路示踪多通道全细胞记录TREM2小胶质细胞杏仁核Neural circuits and networksVirus-mediated circuit tracingMultiple-channel whole-cell recordingMicrogliaAmygdalaSiqiang Ren#Wen Yao#Marc D TambiniTao YinKelly A NorrisLuciano D’Adamio*Si-Qiang RenZhizhong LiSusan LinMatteo BergamiSong-Hai Shi*前额-感觉皮层微环路通信长距离神经连接Xiaohui LvXin-Jun ZhangZhongfu ShenTanay GhoshAnjin XianyuPeng GaoYang YuQiangqiang ZhangMatthias GroszerSong-Hai Shi大脑皮层神经发生与微环路组织Shaoli Wang#Tao Sheng#Siqiang RenTian TianWei Lu*海马长期增强记忆PKCι/λPKMζJing-Zhi YanXiao-Yan ZhangYun-Fei BuWei-Wei PanWen YaoPKCλ在AMPA受体磷酸化和突触整合中的作用Jing-Zhi Yan#Zhuo Xu#Si-Qiang Ren#Bin HuShan-Hui WangSu-Yi Liu蛋白激酶C通过间接触发钙/钙调蛋白依赖性蛋白激酶II自磷酸化促进N-甲基-D-天冬氨酸受体运输研究课题与基金

H 指数:15论文数:52被引数:817

H 指数:42论文数:197被引数:6,480

H 指数:18论文数:114被引数:1,471

H 指数:38论文数:74被引数:7,549

H 指数:35论文数:442被引数:7,534

H 指数:18论文数:47被引数:769

H 指数:24论文数:97被引数:2,110

Xue‐Qiang Wang

H 指数:41论文数:231被引数:5,137

Luciano D'adamio

H 指数:52论文数:144被引数:8,970

Xin‐Jun Zhang

H 指数:18论文数:36被引数:1,796