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A CRISPR-Activation CROP-seq Screen Identifies HMGN1 as a Dosage-Sensitive Regulator of Heart Defects in Down Syndrome CRISPR激活CROP-seq筛选确定了HMGN1是唐氏综合征中心脏缺陷的剂量敏感调节因子 Ranade, Sanjeev; Li, Feiya; Whalen, Sean; Angelo, Pelonero; Ye, Lin; Huang, Yu; Brand, Abigail; Nishino, Tomohiro; Costa, Mauro; Mital, Rahul; Boileau, Ryan; Koback, Frances; Padmanabhan, Arun; Merriman, Alexander; Wallace, Langley; Nguyen, Annie; Poulis, Nikolaus; Gifford, Casey; Pollard, Katherine; Srivastava, Deepak 分享 收藏
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A genome-wide CRISPR screen identifies BRD4 as a regulator of cardiomyocyte differentiation Padmanabhan, Arun; de Soysa, T. Yvanka; Pelonero, Angelo; Sapp, Valerie; Shah, Parisha P.; Wang, Qiaohong; Li, Li; Lee, Clara Youngna; Sadagopan, Nandhini; Nishino, Tomohiro; Ye, Lin; Yang, Rachel; Karnay, Ashley; Poleshko, Andrey; Bolar, Nikhita; Linares-Saldana, Ricardo; Ranade, Sanjeev S.; Alexanian, Michael; Morton, Sarah U.; Jain, Mohit; Haldar, Saptarsi M.; Srivastava, Deepak; Jain, Rajan 分享 收藏
Single-cell multimodal analyses reveal epigenomic and transcriptomic basis for birth defects in maternal diabetes Nishino, Tomohiro; Ranade, Sanjeev S.; Pelonero, Angelo; van Soldt, Benjamin J.; Ye, Lin; Alexanian, Michael; Koback, Frances; Huang, Yu; Wallace, Langley Grace; Sadagopan, Nandhini; Lam, Adrienne; Zholudeva, Lyandysha V.; Li, Feiya; Padmanabhan, Arun; Thomas, Reuben; van Bemmel, Joke G.; Gifford, Casey A.; Costa, Mauro W.; Srivastava, Deepak 分享 收藏
A Mesp1-dependent developmental breakpoint in transcriptional and epigenomic specification of early cardiac precursors Krup, Alexis Leigh; Winchester, Sarah A. B.; Ranade, Sanjeev S.; Agrawal, Ayushi; Devine, W. Patrick; Sinha, Tanvi; Choudhary, Krishna; Dominguez, Martin H.; Thomas, Reuben; Black, Brian L.; Srivastava, Deepak; Bruneau, Benoit G. 分享 收藏
Mechanically activated ion channel PIEZO1 is required for lymphatic valve formation Nonomura, Keiko; Lukacs, Viktor; Sweet, Daniel T.; Goddard, Lauren M.; Kanie, Akemi; Whitwam, Tess; Ranade, Sanjeev S.; Fujimori, Toshihiko; Kahn, Mark L.; Patapoutian, Ardem 分享 收藏
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Piezo1 in Smooth Muscle Cells Is Involved in Hypertension-Dependent Arterial Remodeling 平滑肌细胞中的Piezo1参与高血压依赖性动脉重塑 Retailleau, Kevin; Duprat, Fabrice; Arhatte, Malika; Ranade, Sanjeev Sumant; Peyronnet, Remi; Martins, Joana Raquel; Jodar, Martine; Moro, Celine; Offermanns, Stefan; Feng, Yuanyi; Demolombe, Sophie; Patel, Amanda; Honore, Eric 分享 收藏
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Piezo1, a mechanically activated ion channel, is required for vascular development in mice Piezo1是一种机械激活的离子通道，是小鼠血管发育所必需的。 Ranade, Sanjeev S.; Qiu, Zhaozhu; Woo, Seung-Hyun; Hur, Sung Sik; Murthy, Swetha E.; Cahalan, Stuart M.; Xu, Jie; Mathur, Jayanti; Bandell, Michael; Coste, Bertrand; Li, Yi-Shuan J.; Chien, Shu; Patapoutian, Ardem 分享 收藏
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