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Antibody responses in blood and saliva post COVID-19 bivalent booster do not reveal an Omicron BA.4/BA.5-specific response Baker Jr, Ryan; Lawlor, Rebecca; Smith, Maeve; Price, Jessica; Eaton, Ashley; Lover, Andrew; Alfandari, Dominique; Reinhart, Peter; Arcaro, Kathleen F.; Osborne, Barbara A. 分享 收藏
Potent α-Synuclein Aggregation Inhibitors, Identified by High-Throughput Screening, Mainly Target the Monomeric State Kurnik, Martin; Sahin, Cagla; Andersen, Camilla Bertel; Lorenzen, Nikolai; Giehm, Lise; Mohammad-Beigi, Hossein; Jessen, Christian Moestrup; Pedersen, Jan Skov; Christiansen, Gunna; Petersen, Steen Vang; Staal, Roland; Krishnamurthy, Girija; Pitts, Keith; Reinhart, Peter H.; Mulder, Frans A. A.; Mente, Scot; Hirst, Warren D.; Otzen, Daniel E. 分享 收藏
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Identification of anti-inflammatory targets for Huntington's disease using a brain slice-based screening assay Reinhart, Peter H. p; Kaltenbach, Linda S.; Essrich, Christian; Dunn, Denise E.; Eudailey, Joshua A.; DeMarco, C. Todd; Turmel, Gregory J.; Whaley, Jennifer C.; Wood, Andrew; Cho, Seongeun; Lo, Donald C. 分享 收藏
Inhibition of c-Jun kinase provides neuroprotection in a model of Alzheimer's disease Braithwaite, Steven P.; Schmid, Ralf S.; He, Dong Ning; Sung, Mei-Li A.; Cho, Seongeon; Resnick, Lynn; Monaghan, Michael M.; Hirst, Warren D.; Essrich, Christian; Reinhart, Peter H.; Lo, Donald C. 分享 收藏
Low Resolution Structure of a Membrane-Permeabilizing Oligomer of α-Synuclein: the Basis for a High-Throughput Screening of Compounds against α-Synuclein Aggregation Giehm, Lise; Vestergaard, Bente; Oliveira, Cristiano; Pedersen, Jan S.; Svergun, Dmitri I.; Pitts, Keith; Krishnamurthy, Girija; Staal, Roland; Reinhart, Peter; Otzen, Daniel E. 分享 收藏
Di-substituted pyridinyl aminohydantoins as potent and highly selective human β-secretase (BACE1) inhibitors Malamas, Michael S.; Barnes, Keith; Johnson, Matthew; Hui, Yu; Zhou, Ping; Turner, Jim; Hu, Yun; Wagner, Erik; Fan, Kristi; Chopra, Rajiv; Olland, Andrea; Bard, Jonathan; Pangalos, Menelas; Reinhart, Peter; Robichaud, Albert J. 分享 收藏
Dimebon™ is neuroprotective in a model of Parkinson's disease Staal, R. G. W.; Kubek, K.; Sung, A.; Lin, Q.; DenBleyker, M.; Monaghan, M.; Martone, R.; Robichaud, A. J.; Haydar, S. N.; Pangalos, M.; Reinhart, P. H.; Hirst, W. D. 分享 收藏
Modeling synucleinopathies: intracellular delivery of alpha-synuclein oligomers via protein transfection results in intracellular alpha-synuclein inclusions Martone, R.; Meehan, J.; Xu, J. Z.; Mercado, M. L.; Staal, R.; Hubbell, A.; Kubek, K.; Nawoschik, S.; Das, I.; Shih, H.; Dunlop, J.; Pangalos, M.; Reinhart, P. 分享 收藏
Begacestat (GSI-953): A Novel, Selective Thiophene Sulfonamide Inhibitor of Amyloid Precursor Protein γ-Secretase for the Treatment of Alzheimer's Disease Martone, Robert L.; Zhou, Hua; Atchison, Kevin; Comery, Thomas; Xu, Jane Z.; Huang, Xinyi; Gong, Xioahai; Jin, Mei; Kreft, Anthony; Harrison, Boyd; Mayer, Scott C.; Aschmies, Suzan; Gonzales, Cathleen; Zaleska, Margaret M.; Riddell, David R.; Wagner, Erik; Lu, Peimin; Sun, Shaiu-Ching; Sonnenberg-Reines, June; Oganesian, Aram; Adkins, Karissa; Leach, Michael W.; Clarke, David W.; Huryn, Donna; Abou-Gharbia, Magid; Magolda, Ronald; Bard, Jonathan; Frick, Glen; Raje, Sangeeta; Forlow, S. Bradley; Balliet, Carrie; Burczynski, Michael E.; Reinhart, Peter H.; Wan, Hong I.; Pangalos, Menelas N.; Jacobsen, J. Steven 分享 收藏
Investigation of leucine-rich repeat kinase 2 Anand, Vasanti S.; Reichling, Laurie J.; Lipinski, Kerri; Stochaj, Wayne; Duan, Weili; Kelleher, Kerry; Pungaliya, Pooja; Brown, Eugene L.; Reinhart, Peter H.; Somberg, Richard; Hirst, Warren D.; Riddle, Steven M.; Braithwaite, Steven P. 分享 收藏
Discovery of Begacestat, a Notch-1-Sparing γ-Secretase Inhibitor for the Treatment of Alzheimer's Disease Mayer, Scott C.; Kreft, Anthony F.; Harrison, Boyd; Abou-Gharbia, Magid; Antane, Madelene; Aschmies, Suzan; Atchison, Kevin; Chlenov, Michael; Cole, Derek C.; Comery, Thomas; Diamantidis, George; Ellingboe, John; Fan, Kristi; Galante, Rocco; Gonzales, Cathleen; Ho, Douglas M.; Hoke, Molly E.; Hu, Yun; Huryn, Donna; Jain, Uday; Jin, Mei; Kremer, Kenneth; Kubrak, Dennis; Lin, Melissa; Lu, Peimin; Magolda, Ron; Martone, Robert; Moore, William; Oganesian, Aram; Pangalos, Menelas N.; Porte, Alex; Reinhart, Peter; Resnick, Lynn; Riddell, David R.; Sonnenberg-Reines, June; Stock, Joseph R.; Sun, Shaiu-Ching; Wagner, Erik; Wang, Ting; Woller, Kevin; Xu, Zheng; Zaleska, Margaret M.; Zeldis, Joseph; Zhang, Minsheng; Zhou, Hua; Jacobsen, J. Steven 分享 收藏
Enhanced clearance of Aβ in brain by sustaining the plasmin proteolysis cascade Jacobsen, J. Steven; Comery, Thomas A.; Martone, Robert L.; Elokdah, Hassan; Crandall, David L.; Oganesian, Aram; Aschmies, Suzan; Kirksey, Yolanda; Gonzales, Cathleen; Xu, Jane; Zhou, Hua; Atchison, Kevin; Wagner, Erik; Zaleska, Margaret M.; Das, Indranil; Arias, Robert L.; Bard, Jonathan; Riddell, David; Gardell, Stephen J.; Abou-Gharbia, Magid; Robichaud, Albert; Magolda, Ronald; Vlasuk, George P.; Bjornsson, Thorir; Reinhart, Peter H.; Pangalos, Menelas N. 分享 收藏
Binding of rapamycin analogs to channels and FKBP52 contributes their neuroprotective activities Ruan, Benfang; Pong, Kevin; Jow, Flora; Bowlby, Mark; Crozier, Robert A.; Liu, Danni; Liang, Shi; Chen, Yi; Mercado, Mary Lynn; Feng, Xidong; Bennettt, Frann; von Schack, David; McDonald, Leonard; Zaleska, Margaret M.; Wood, Andrew; Reinhart, Peter H.; Magolda, Ronald L.; Skotnicki, Jerauld; Pangalos, Menelas N.; Koehn, Frank E.; Carter, Guy T.; Abou-Gharbia, Magid; Graziani, Edmund I. 分享 收藏
Early-onset behavioral and synaptic deficits in a mouse model of Alzheimer's disease 阿尔茨海默氏病小鼠模型的早发行为和突触缺陷 Jacobsen, JS; Wu, CC; Redwine, JM; Comery, TA; Arias, R; Bowlby, M; Martone, R; Morrison, JH; Pangalos, MN; Reinhart, PH; Bloom, FE 分享 收藏
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