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C

Charles A. Brearley

instituto de quimica fisica blas cabrera

41H指数
125论文数
5.7K被引数
收录论文 69
发表时间
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The Diphosphoinositol Polyphosphate Phosphohydrolase 1 family binds IP8 in catalytically-productive twist-boat and chair conformations and associates in a ligand-dependent manner二磷酸肌醇多磷酸磷酸水解酶1家族以催化活性扭曲-船式和椅式构象结合IP8，并以配体依赖方式发生关联
errInternational Journal of Biological Macromolecules
IF8.5
err2026-06-01
err0
PREAI
errCasas-Florez, David; Whitfield, Hayley; Perez-Canadillas, Jose M.; Monterroso, Begona; Riley, Andrew M.; Monino, Maria A. Marquez; Shipton, Megan L.; Sanz-Aparicio, Julia; Brearley, Charles A.; Potter, Barry V. L.; Gonzalez, Beatriz
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Rethinking the maximum inclusion levels of exogenous phytase for enhanced turkey production performance重新审视外源性植酸酶的最大添加量以提升火鸡生产性能
errArchives of Animal Nutrition
IF1.5
err2026-05-01
err0
PREAI
errPirgozliev, Vasil R.; Mansbridge, Stephen C.; Whiting, Isobel M.; Rose, Stephen P.; Brearley, Charles A.; Bedford, Michael R.
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The intracellular inositol (pyro)phosphate receptor AtSPX1 reciprocally binds to P1BS DNA细胞内肌醇（焦）磷酸受体AtSPX1与P1BS DNA发生相互结合
errNature Communications
IF15.7
err2026-02-24
err0
errOAAI
errHayley L. Whitfield; Megan Gilmartin; Andrew M. Riley; Megan L. Shipton; Barry V. L. Potter; Andrew M. Hemmings; Charles A. Brearley
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A minimum catalytic unit for synthesis of InsP6 and 5-PP-InsP5 in Arabidopsis拟南芥中合成InsP6和5-PP-InsP5所需的最小催化单元
errBIOCHEMICAL JOURNAL
IF4.3
err2025-12-01
err0
errOAAI
errWhitfield, Hayley L.; Sprigg, Colleen; Riley, Andrew M.; Potter, Barry V. L.; Kuo, Hui-Fen; Brearley, Charles A.
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Phosphorus-specific, liquid chromatography inductively coupled plasma mass spectrometry for analysis of inositol phosphate and inositol pyrophosphate metabolism
errBIOCHEMICAL JOURNAL
IF4.3
err2025-11-01
err0
errOAAI
errSprigg, Colleen; Whitfield, Hayley L.; Leftwich, Philip T.; Kuo, Hui-Fen; Chiou, Tzyy-Jen; Saiardi, Adolfo; Shipton, Megan L.; Riley, Andrew M.; Potter, Barry V. L.; Scholey, Dawn; Burton, Emily; Bedford, Mike R.; Brearley, Charles A.
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Effects of phytase supplementation on energy and nutrient availability, and phytate degradation in turkeys植酸酶补充对火鸡能量和营养素利用率以及植酸降解的影响
errPoultry Science
IF4.2
err2025-05-16
err0
errOAAI
errV. Pirgozliev; S.C. Mansbridge; E.S. Watts; I.M. Whiting; S.P. Rose; C.A. Brearley; M.R. Bedford
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The inositol phosphate signalling network in physiology and disease生理学和疾病中的肌醇磷酸信号网络
errTRENDS IN BIOCHEMICAL SCIENCES
IF11
err2024-11-01
err1
errOAAI
errKim, Seyun; Bhandari, Rashna; Brearley, Charles A.; Saiardi, Adolfo
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Elucidation of Spartina dimethylsulfoniopropionate synthesis genes enables engineering of stress tolerant plants
errNATURE COMMUNICATIONS
IF15.7
err2024-10-09
err0
errOAAI
errPayet, Rocky D.; Bilham, Lorelei J.; Kabir, Shah Md Tamim; Monaco, Serena; Norcott, Ash R.; Allen, Mellieha G. E.; Zhu, Xiao-Yu; Davy, Anthony J.; Brearley, Charles A.; Todd, Jonathan D.; Miller, J. Benjamin
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Optimized barley phytase gene expression by focused FIND-IT screening for mutations in cis-acting regulatory elements通过聚焦的FIND-IT筛选顺式作用调控元件中的突变来优化大麦植酸酶基因表达
errFRONTIERS IN PLANT SCIENCE
IF4.8
err2024-03-01
err2
errOAAI
errMadsen, Claus Krogh; Brearley, Charles Alistair; Harholt, Jesper; Brinch-Pedersen, Henrik
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Substrate promiscuity of inositol 1,4,5-trisphosphate kinase driven by structurally-modified ligands and active site plasticity
errNATURE COMMUNICATIONS
IF15.7
err2024-02-19
err2
errOAAI
errMarquez-Monino, Maria Angeles; Ortega-Garcia, Raquel; Whitfield, Hayley; Riley, Andrew M.; Infantes, Lourdes; Garrett, Shane W.; Shipton, Megan L.; Brearley, Charles A.; Potter, Barry V. L.; Gonzalez, Beatriz
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LC-ICP-MS analysis of inositol phosphate isomers in soil offers improved sensitivity and fine-scale mapping of inositol phosphate distribution
errMETHODS IN ECOLOGY AND EVOLUTION
IF6.2
err2024-02-04
err2
errOAAI
errCarroll, Joseph J.; Sprigg, Colleen; Chilvers, Graham; Delso, Ignacio; Barker, Megan; Cox, Filipa; Johnson, David; Brearley, Charles A.
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Diversification in the inositol tris/tetrakisphosphate kinase (ITPK) family: crystal structure and enzymology of the outlier AtITPK4
errBIOCHEMICAL JOURNAL
IF4.3
err2023-03-29
err6
errOAAI
errWhitfield, Hayley L.; He, Sining; Gu, Yinghong; Sprigg, Colleen; Kuo, Hui -Fen; Chiou, Tzyy-Jen; Riley, Andrew M.; Potter, Barry V. L.; Hemmings, Andrew M.; Brearley, Charles A.
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Rapeseed meal processing and dietary enzymes modulate excreta inositol phosphate profile, nutrient availability, and production performance of broiler chickens
errPOULTRY SCIENCE
IF4.2
err2022-10-01
err4
errOAAI
errPirgozliev, V. R.; Mansbridge, S. C.; Kendal, T.; Watts, E. S.; Rose, S. P.; Brearley, C. A.; Bedford, M. R.
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Structure of a cereal purple acid phytase provides new insights to phytate degradation in plants谷物紫色酸性植酸酶的结构为植物中植酸盐的降解提供了新的见解
errPLANT COMMUNICATIONS
IF11.6
err2022-03-01
err6
errOAAI
errFaba-Rodriguez, Raquel; Gu, Yinghong; Salmon, Melissa; Dionisio, Giuseppe; Brinch-Pedersen, Henrik; Brearley, Charles A.; Hemmings, Andrew M.
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Allosteric Site on SHIP2 Identified Through Fluorescent Ligand Screening and Crystallography: A Potential New Target for Intervention
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2021-03-16
err5
errOAAI
errWhitfield, Hayley; Hemmings, Andrew M.; Mills, Stephen J.; Baker, Kendall; White, Gaye; Rushworth, Stuart; Riley, Andrew M.; Potter, Barry V. L.; Brearley, Charles A.
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Improved sensitivity, accuracy and prediction provided by a high-performance liquid chromatography screen for the isolation of phytase-harbouring organisms from environmental samples
errMICROBIAL BIOTECHNOLOGY
IF5.2
err2020-12-21
err5
errOAAI
errRix, Gregory D.; Todd, Jonathan D.; Neal, Andrew L.; Brearley, Charles A.
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Snapshots during the catalytic cycle of a histidine acid phytase reveal an induced-fit structural mechanism
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2020-12-01
err11
errOAAI
errAcquistapace, Isabella M.; Zietek, Monika A.; Li, Arthur W. H.; Salmon, Melissa; Kuhn, Imke; Bedford, Mike R.; Brearley, Charles A.; Hemmings, Andrew M.
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An ATP-responsive metabolic cassette comprised of inositol tris/tetrakisphosphate kinase 1 (ITPK1) and inositol pentakisphosphate 2-kinase (IPK1) buffers diphosphosphoinositol phosphate levels
errBIOCHEMICAL JOURNAL
IF4.3
err2020-07-24
err35
errOAAI
errWhitfield, Hayley; White, Gaye; Sprigg, Colleen; Riley, Andrew M.; Potter, Barry V. L.; Hemmings, Andrew M.; Brearley, Charles A.
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Both D- and L-Glucose Polyphosphates Mimic D-myo-Inositol 1,4,5-Trisphosphate: New Synthetic Agonists and Partial Agonists at the Ins(1,4,5)P3 Receptor
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2020-04-14
err9
errOAAI
errShipton, Megan L.; Riley, Andrew M.; Rossi, Ana M.; Brearley, Charles A.; Taylor, Colin W.; Potter, Barry V. L.
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Regioisomeric Family of Novel Fluorescent Substrates for SHIP2
errACS MEDICINAL CHEMISTRY LETTERS
IF4
err2019-10-18
err1
errOAAI
errWhite, Gaye; Prior, Christopher; Mills, Stephen J.; Baker, Kendall; Whitfield, Hayley; Riley, Andrew M.; Oganesyan, Vasily S.; Potter, Barry V. L.; Brearley, Charles A.
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研究方向

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合作学者
合作期刊
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Glenn D. Prestwich
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