Steven O. Smith - Publications, H-index & Citations

Steven O. Smith

stony brook university

71H指数

225论文数

1.6W被引数

收录论文 88

发表时间

Molecular and functional characterization of the retinitis pigmentosa G90V mutation in a conformationally stabilized rhodopsin background 在构象稳定视杆蛋白背景下的色素性视网膜炎G90V突变的分子和功能表征

International Journal of Biological Macromolecules

IF8.5

2025-10-04

OAAI

Pol Fernandez-Gonzalez; Sylwia Jencz; Steven O. Smith; Philip J. Reeves; Pere Garriga

Aβ40 Fibril Assembly on Human Cerebral Smooth Muscle Cells Impairs Cell Viability Aβ40 纤维在人类脑平滑肌细胞上的组装损害细胞活力

BIOCHEMISTRY

IF3

2025-01-06

PREAI

Irizarry, Brandon; Davis, Judianne; Rajpoot, Jitika; Zhu, Xiaoyue; Xu, Feng; Smith, Steven O.; Van Nostrand, William E.

Author Correction: Cerebral vascular amyloid seeds drive amyloid β-protein fibril assembly with a distinct anti-parallel structure (vol 1 ,6089 ,2024)

NATURE COMMUNICATIONS

IF15.7

2024-07-19

OAAI

Xu, Feng; Fu, Ziao; Dass, Sharmila; Kotarba, AnnMarie E.; Davis, Judianne; Smith, Steven O.; Van Nostrand, William E.

An electrostatic cluster guides Aβ40 fibril formation in sporadic and Dutch-type cerebral amyloid angiopathy

JOURNAL OF STRUCTURAL BIOLOGY

IF5.1

2024-06-01

OAAI

Fu, Ziao; Crooks, Elliot J.; Irizarry, Brandon A.; Zhu, Xiaoyue; Chowdhury, Saikat; Van Nostrand, William E.; Smith, Steven O.

Constitutive activation and oncogenicity are mediated by loss of helical structure at the cytosolic boundary of thrombopoietin receptor mutant dimers

ELIFE

IF0

2023-06-20

OAAI

Defour, Jean-Philippe; Leroy, Emilie; Dass, Sharmila; Balligand, Thomas; Levy, Gabriel; Brett, Ian C.; Papadopoulos, Nicolas; Mouton, Celine; Genet, Lidvine; Pecquet, Christian; Staerk, Judith; Smith, Steven O.; Constantinescu, Stefan N.; Kay, Lewis E.

Impact of Aβ40 and Aβ42 Fibrils on the Transcriptome of Primary Astrocytes and Microglia

BIOMEDICINES

IF3.9

2022-11-19

OAAI

Zhu, Xiaoyue; Schrader, Joseph M.; Irizarry, Brandon A.; Smith, Steven O.; Van Nostrand, William E.

Magic angle spinning NMR of G protein-coupled receptors G蛋白偶联受体的魔角旋转核磁共振

Progress in Nuclear Magnetic Resonance Spectroscopy

IF8.2

2022-02-01

OAAI

Chandler, Bianca; Todd, Lauren; Smith, Steven O.

Deconstructing the transmembrane core of class A G protein-coupled receptors

TRENDS IN BIOCHEMICAL SCIENCES

IF11

2021-12-01

OAAI

Smith, Steven O.

Human cerebral vascular amyloid contains both antiparallel and parallel in-register Aβ40 fibrils

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2021-11-01

OAAI

Irizarry, Brandon A.; Davis, Judianne; Zhu, Xiaoyue; Boon, Baayla D. C.; Rozemuller, Annemieke J. M.; Van Nostrand, William E.; Smith, Steven O.

Copper stabilizes antiparallel ?-sheet fibrils of the amyloid?40 (A?40)-Iowa variant

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2020-07-01

OAAI

Crooks, Elliot J.; Irizarry, Brandon A.; Ziliox, Martine; Kawakami, Toru; Victor, Tiffany; Xu, Feng; Hojo, Hironobu; Chiu, Kelley; Simmerling, Carlos; Van Nostrand, William E.; Smith, Steven O.; Miller, Lisa M.

Influence of the familial Alzheimer's disease-associated T43I mutation on the transmembrane structure and -secretase processing of the C99 peptide

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2019-04-01

OAAI

Tang, Tzu-Chun; Kienlen-Campard, Pascal; Hu, Yi; Perrin, Florian; Opsomer, Remi; Octave, Jean-Noel; Constantinescu, Stefan N.; Smith, Steven O.

The S505A thrombopoietin receptor mutation in childhood hereditary thrombocytosis and essential thrombocythemia is S505N: single letter amino acid code matters

LEUKEMIA

IF13.4

2019-01-11

PREAI

Defour, Jean-Philippe; Levy, Gabriel; Leroy, Emilie; Smith, Steven O.; Constantinescu, Stefan N.

β-Sheet Structure within the Extracellular Domain of C99 Regulates Amyloidogenic Processing

SCIENTIFIC REPORTS

IF3.9

2017-12-07

OAAI

Hu, Yi; Kienlen-Campard, Pascal; Tang, Tzu-Chun; Perrin, Florian; Opsomer, Remi; Decock, Marie; Pan, Xiaoshu; Octave, Jean-Noel; Constantinescu, Stefan N.; Smith, Steven O.

G Protein-Coupled Receptors Contain Two Conserved Packing Clusters

BIOPHYSICAL JOURNAL

IF3.1

2017-06-01

OAAI

Sanchez-Reyes, Omar B.; Cooke, Aidan L. G.; Tranter, Dale B.; Rashid, Dawood; Eilers, Markus; Reeves, Philip J.; Smith, Steven O.

Cerebral vascular amyloid seeds drive amyloid β-protein fibril assembly with a distinct anti-parallel structure

NATURE COMMUNICATIONS

IF15.7

2016-11-21

OAAI

Xu, Feng; Fu, Ziao; Dass, Sharmila; Kotarba, AnnMarie E.; Davis, Judianne; Smith, Steven O.; Van Nostrand, William E.

Retinal orientation and interactions in rhodopsin reveal a two-stage trigger mechanism for activation

NATURE COMMUNICATIONS

IF15.7

2016-09-02

OAAI

Kimata, Naoki; Pope, Andreyah; Eilers, Markus; Opefi, Chikwado A.; Ziliox, Martine; Hirshfeld, Amiram; Zaitseva, Ekaterina; Vogel, Reiner; Sheves, Mordechai; Reeves, Philip J.; Smith, Steven O.

Free backbone carbonyls mediate rhodopsin activation 游离主链羰基介导视紫红质活化

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2016-07-04

OAAI

Kimata, Naoki; Pope, Andreyah; Sanchez-Reyes, Omar B.; Eilers, Markus; Opefi, Chikwado A.; Ziliox, Martine; Reeves, Philip J.; Smith, Steven O.

Glycines from the APP GXXXG/GXXXA Transmembrane Motifs Promote Formation of Pathogenic Aβ Oligomers in Cells

FRONTIERS IN AGING NEUROSCIENCE

IF4.5

2016-05-10

OAAI

Decock, Marie; Stanga, Serena; Octave, Jean-Noel; Dewachter, Ilse; Smith, Steven O.; Constantinescu, Stefan N.; Kienlen-Campard, Pascal

His499 Regulates Dimerization and Prevents Oncogenic Activation by Asparagine Mutations of the Human Thrombopoietin Receptor

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2016-02-01

OAAI

Leroy, Emilie; Defour, Jean-Philippe; Sato, Takeshi; Dass, Sharmila; Gryshkova, Vitalina; Shwe, Myat M.; Staerk, Judith; Constantinescu, Stefan N.; Smith, Steven O.

Presenilin Transmembrane Domain 8 Conserved AXXXAXXXG Motifs Are Required for the Activity of the γ-Secretase Complex

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2015-03-01

OAAI

Marinangeli, Claudia; Tasiaux, Bernadette; Opsomer, Remi; Hage, Salim; Sodero, Alejandro O.; Dewachter, Ilse; Octave, Jean Noel; Smith, Steven O.; Constantinescu, Stefan N.; Kienlen-Campard, Pascal

研究方向