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J

Janet E. Deane

University of Cambridge
H指数:29
被引数:2,792
浏览量:0

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Herpes simplex virus pUL56 abolishes neuronal activity by removing voltage-gated ion channels from the plasma membrane

单纯疱疹病毒pUL56通过从细胞膜中移除电压门控离子通道来抑制神经元活动

Science Advances
IF12.5
2026-01-010
PRE
Daniel A Nash; Henry G. Barrow; Robin Antrobus; Alex S. Nicholson; John Suberu; Harvey E. Johnston; Martin O.P. Potts; Marta A. Almeida; Valeria Lulla; Colin M. Crump; Anton James Enright; Michael P. Weekes; Janet Elwyn Deane; Stephen C. Graham
Optimization of lytic herpes simplex virus infection in human induced pluripotent stem cell-derived cortical neurones

优化溶菌性单纯疱疹病毒在人诱导多能干细胞来源的大脑皮层神经元中的感染

Journal of General Virology
IF4.3
2026-01-010
PRE
Nash, Daniel A.; Nicholson, Alex S.; Barrow, Henry G.; Connor, Viv; Crump, Colin M.; Deane, Janet E.; Graham, Stephen C.
Alphaherpesvirus pUL21 homologues use non-canonical sequences to compete with cellular adaptors for protein phosphatase 1 binding

α疱疹病毒pUL21同源物利用非经典序列与细胞适配器竞争蛋白磷酸酶1的结合。

Journal of Biological Chemistry
IF3.9
2025-11-120
OAAI
Holly Monkhouse; Daniela S. Carter-Lopez; Tomasz H. Benedyk; Janet E. Deane; Stephen C. Graham
Linking glycosphingolipid metabolism to disease-related changes in the plasma membrane proteome
BIOCHEMICAL SOCIETY TRANSACTIONS
IF4.3
2024-12-061
OAAI
Monkhouse, Holly; Deane, Janet E.
Zika viruses encode 5′ upstream open reading frames affecting infection of human brain cells
NATURE COMMUNICATIONS
IF15.7
2024-10-120
OAAI
Lefevre, Charlotte; Cook, Georgia M.; Dinan, Adam M.; Torii, Shiho; Stewart, Hazel; Gibbons, George; Nicholson, Alex S.; Echavarria-Consuegra, Liliana; Meredith, Luke W.; Lulla, Valeria; Mcgovern, Naomi; Kenyon, Julia C.; Goodfellow, Ian; Deane, Janet E.; Graham, Stephen C.; Lakatos, Andras; Lambrechts, Louis; Brierley, Ian; Irigoyen, Nerea
The structure of a Plasmodium vivax Tryptophan Rich Antigen domain suggests a lipid binding function for a pan-Plasmodium multi-gene family
NATURE COMMUNICATIONS
IF15.7
2023-09-142
OAAI
Kundu, Prasun; Naskar, Deboki; Mckie, Shannon J.; Dass, Sheena; Kanjee, Usheer; Introini, Viola; Ferreira, Marcelo U.; Cicuta, Pietro; Duraisingh, Manoj; Deane, Janet E.; Rayner, Julian C.
Altered plasma membrane abundance of the sulfatide-binding protein NF155 links glycosphingolipid imbalances to demyelination
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2023-03-301
OAAI
McKie, Shannon J.; Nicholson, Alex S.; Smith, Emily; Fawke, Stuart; Caroe, Eve R.; Williamson, James C.; Butt, Benjamin G.; Kolarova, Denisa; Peterka, Ondrej; Holcapek, Michal; Lehner, Paul J.; Graham, Stephen C.; Deane, Janet E.
Determinants of receptor tyrosine phosphatase homophilic adhesion: Structural comparison of PTPRK and PTPRM extracellular domains
JOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
2023-01-012
OAAI
Hay, Iain M.; Shamin, Maria; Caroe, Eve R.; Mohanned, Ahmed S. A.; Svergun, Dmitri I.; Jeffries, Cy M.; Graham, Stephen C.; Sharpe, Hayley J.; Deane, Janet E.
Herpes simplex virus 1 protein pUL21 alters ceramide metabolism by activating the interorganelle transport protein CERT

单纯疱疹病毒1蛋白pUL21通过激活细胞器间转运蛋白CERT改变神经酰胺代谢

JOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
2022-11-0113
OAAI
Benedyk, Tomasz H.; Connor, Viv; Caroe, Eve R.; Shamin, Maria; Svergun, Dmitri I.; Deane, Janet E.; Jeffries, Cy M.; Crump, Colin M.; Graham, Stephen C.
Molecular mechanism of Afadin substrate recruitment to the receptor phosphatase PTPRK via its pseudophosphatase domain

Afadin底物通过其假磷酸酶结构域募集到受体磷酸酶PTPRK的分子机制

ELIFE
IF0
2022-10-202
OA
Hay, Iain M.; Mulholland, Katie E.; Lai, Tiffany; Graham, Stephen C.; Sharpe, Hayley J.; Deane, Janet E.
The crystal structure of vaccinia virus protein E2 and perspectives on the prediction of novel viral protein folds
JOURNAL OF GENERAL VIROLOGY
IF4.3
2022-01-216
OAAI
Gao, William N. D.; Gao, Chen; Deane, Janet E.; Carpentier, David C. J.; Smith, Geoffrey L.; Graham, Stephen C.
pUL21 is a viral phosphatase adaptor that promotes herpes simplex virus replication and spread (vol 17, e1009824, 2021)
PLOS PATHOGENS
IF4.9
2022-01-060
OAAI
Benedyk, Tomasz H.; Muenzner, Julia; Connor, Viv; Han, Yue; Brown, Katherine; Wijesinghe, Kaveesha J.; Zhuang, Yunhui; Colaco, Susanna; Stoll, Guido A.; Tutt, Owen S.; Svobodova, Stanislava; Svergun, Dmitri I.; Bryant, Neil A.; Deane, Janet E.; Firth, Andrew E.; Jeffries, Cy M.; Crump, Colin M.; Graham, Stephen C.
pUL21 is a viral phosphatase adaptor that promotes herpes simplex virus replication and spread
PLOS PATHOGENS
IF4.9
2021-08-1618
OAAI
Benedyk, Tomasz H.; Muenzner, Julia; Connor, Viv; Han, Yue; Brown, Katherine; Wijesinghe, Kaveesha J.; Zhuang, Yunhui; Colaco, Susanna; Stoll, Guido A.; Tutt, Owen S.; Svobodova, Stanislava; Svergun, Dmitri I.; Bryant, Neil A.; Deane, Janet E.; Firth, Andrew E.; Jeffries, Cy M.; Crump, Colin M.; Graham, Stephen C.
The Bicyclic Form of galacto-Noeurostegine Is a Potent Inhibitor of β-Galactocerebrosidase
ACS MEDICINAL CHEMISTRY LETTERS
IF4
2020-12-180
OA
Viuff, Agnete; Salamone, Stephane; McLoughlin, Joseph; Deane, Janet E.; Jensen, Henrik H.
The receptor PTPRU is a redox sensitive pseudophosphatase
NATURE COMMUNICATIONS
IF15.7
2020-06-2620
OAAI
Hay, Iain M.; Fearnley, Gareth W.; Rios, Pablo; Koehn, Maja; Sharpe, Hayley J.; Deane, Janet E.
Antagonism of PP2A is an independent and conserved function of HIV-1 Vif and causes cell cycle arrest
ELIFE
IF0
2020-04-1522
OAAI
Marelli, Sara; Williamson, James C.; Protasio, Anna, V; Naamati, Adi; Greenwood, Edward J. D.; Deane, Janet E.; Lehner, Paul J.; Matheson, Nicholas J.
Molecular models should not be published without the corresponding atomic coordinates
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2019-06-043
OAAI
Graham, Stephen C.; Nagar, Bhushan; Prive, Gilbert G.; Deane, Janet E.
The homophilic receptor PTPRK selectively dephosphorylates multiple junctional regulators to promote cell-cell adhesion
ELIFE
IF0
2019-03-2929
OA
Fearnley, Gareth W.; Young, Katherine A.; Edgar, James R.; Antrobus, Robin; Hay, Iain M.; Liang, Wei-Ching; Martinez-Martin, Nadia; Lin, WeiYu; Deane, Janet E.; Sharpe, Hayley J.
TAPBPR mediates peptide dissociation from MHC class I using a leucine lever
ELIFE
IF0
2018-11-2837
OA
Ilca, F. Tudor; Neerincx, Andreas; Hermann, Clemens; Marcu, Ana; Stevanovic, Stefan; Deane, Janet E.; Boyle, Louise H.
The mechanism of glycosphingolipid degradation revealed by a GALC-SapA complex structure
NATURE COMMUNICATIONS
IF15.7
2018-01-1140
OAAI
Hill, Chris H.; Cook, Georgia M.; Spratley, Samantha J.; Fawke, Stuart; Graham, Stephen C.; Deane, Janet E.

研究方向

暂未获取到该数据
S
Stephen C. Graham
H 指数:45论文数:188被引数:6,154
S
Susan M. Lea
H 指数:69论文数:487被引数:1.4万
S
Steven Johnson
H 指数:47论文数:180被引数:7,237
C
Cy M. Jeffries
H 指数:37论文数:166被引数:7,742
D
Dmitri I. Svergun
H 指数:99论文数:829被引数:6.4万
C
Colin M. Crump
H 指数:33论文数:89被引数:3,707
C
Chris H. Hill
H 指数:21论文数:64被引数:1,363
I
Iain M. Hay
H 指数:5论文数:17被引数:211
H
Hayley J. Sharpe
H 指数:17论文数:75被引数:2,768
R
Randy J. Read
H 指数:81论文数:361被引数:12.8万