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H

Hayley J. Sharpe

babraham institute
H指数:17
被引数:2,768
浏览量:0

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Pervanadate-induced oxidation relieves autoinhibition of the protein tyrosine kinase SRC
Science Signaling
IF6.6
2026-01-200
PRE
Katie E. Mulholland; Maxime Bourguet; Nuo Cheng; Oisharja Rahman; Daria Ezeriņa; Leonard A. Daly; Tiffany Lai; Silvia Aldaz Casanova; Therese Featherston; Pau Creixell; Claire E. Eyers; Joris Messens; Patrick A. Eyers; Dominic P. Byrne; Hayley J. Sharpe
Pancreatic CAF-Derived Autotaxin Drives Autocrine CTGF Expression to Modulate Protumorigenic Signaling
MOLECULAR CANCER THERAPEUTICS
IF5.5
2024-11-210
PRE
Volat, Fanny; Medhi, Ragini; Maggs, Lauren Z.; Deken, Marcel A.; Price, Alice; Andrews, Lauren; Clark, Jonathan; Taylor, Diane; Carruthers, Alan; Taylor-Smith, Ewan; Pacheco, Natalia; Rudge, Simon A.; Fraser, Amy; Lopez-Clavijo, Andrea F.; Sousa, Bebiana C.; Johnson, Zoe; Di Conza, Giusy; van der Veen, Lars; Shah, Pritom; Sandig, Hilary; Sharpe, Hayley J.; Farrow, Stuart
PTPRK regulates glycolysis and de novo lipogenesis to promote hepatocyte metabolic reprogramming in obesity
NATURE COMMUNICATIONS
IF15.7
2024-11-040
OAAI
Gilglioni, Eduardo H.; Li, Ao; St-Pierre-Wijckmans, Wadsen; Shen, Tzu-Keng; Perez-Chavez, Israel; Hovhannisyan, Garnik; Lisjak, Michela; Negueruela, Javier; Vandenbempt, Valerie; Bauza-Martinez, Julia; Herranz, Jose M.; Ezerina, Daria; Demine, Stephane; Feng, Zheng; Vignane, Thibaut; Otero Sanchez, Lukas; Lambertucci, Flavia; Prasnicka, Alena; Deviere, Jacques; Hay, David C.; Encinar, Jose A.; Singh, Sumeet Pal; Messens, Joris; Filipovic, Milos R.; Sharpe, Hayley J.; Trepo, Eric; Wu, Wei; Gurzov, Esteban N.
The receptor protein tyrosine phosphatase PTPRK promotes intestinal repair and catalysis-independent tumour suppression
JOURNAL OF CELL SCIENCE
IF3.6
2024-07-220
OAAI
Young, Katherine A.; Wojdyla, Katarzyna; Lai, Tiffany; Mulholland, Katie E.; Casanova, Silvia Aldaz; Antrobus, Robin; Andrews, Simon R.; Biggins, Laura; Mahler-Araujo, Betania; Barton, Philippa R.; Anderson, Keith R.; Fearnley, Gareth W.; Sharpe, Hayley J.
Accelerated waning of the humoral response to COVID-19 vaccines in obesity
NATURE MEDICINE
IF50
2023-05-1138
OAAI
van der Klaauw, Agatha C.; Horner, Emily; Pereyra-Gerber, Pehuen; Agrawal, Utkarsh S.; Foster, William; Spencer, Sarah; Vergese, Bensi; Smith, Miriam; Henning, Elana D.; Ramsay, Isobel A.; Smith, Jack M.; Guillaume, Stephane J.; Sharpe, Hayley M.; Hay, Iain; Thompson, Sam; Innocentin, Silvia H.; Booth, Lucy; Robertson, Chris; McCowan, Colin; Kerr, Steven; Mulroney, Thomas J.; O'Reilly, Martin P.; Gurugama, Thevinya P.; Gurugama, Lihinya A.; Rust, Maria; Ferreira, Alex; Ebrahimi, Soraya; Ceron-Gutierrez, Lourdes; Scotucci, Jacopo; Kronsteiner, Barbara J.; Dunachie, Susanna; Klenerman, Paul J.; Park, Adrian A.; Rubino, Francesco; Lamikanra, Abigail; Stark, Hannah; Kingston, Nathalie; Estcourt, Lise; Harvala, Heli; Roberts, David A.; Doffinger, Rainer J.; Linterman, Michelle; Matheson, Nicholas; Sheikh, Aziz; Farooqi, I. Sadaf; Thaventhiran, James E. D.
ChAdOx1 nCoV-19 vaccination generates spike-specific CD8+ T cells in aged mice

ChAdOx1 nCoV-19疫苗在老年小鼠中产生刺突特异性CD8 T细胞

IMMUNOLOGY AND CELL BIOLOGY
IF3
2023-05-060
OA
Foster, William S.; Newman, Joseph; Thakur, Nazia; Spencer, Alexandra J.; Davies, Sophie; Woods, Danielle; Godfrey, Leila; Ross, Sarah H.; Sharpe, Hayley J.; Richard, Arianne C.; Bailey, Dalan; Lambe, Teresa; Linterman, Michelle A.
Determinants of receptor tyrosine phosphatase homophilic adhesion: Structural comparison of PTPRK and PTPRM extracellular domains
JOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
2023-01-012
OAAI
Hay, Iain M.; Shamin, Maria; Caroe, Eve R.; Mohanned, Ahmed S. A.; Svergun, Dmitri I.; Jeffries, Cy M.; Graham, Stephen C.; Sharpe, Hayley J.; Deane, Janet E.
Tfh cells and the germinal center are required for memory B cell formation & humoral immunity after ChAdOx1 nCoV-19 vaccination
CELL REPORTS MEDICINE
IF10.6
2022-12-0111
OAAI
Foster, William S.; Lee, Jia Le; Thakur, Nazia; Newman, Joseph; Spencer, Alexandra J.; Davies, Sophie; Woods, Danielle; Godfrey, Leila; Hay, Iain M.; Innocentin, Silvia; Yam-Puc, Juan Carlos; Horner, Emily C.; Sharpe, Hayley J.; Thaventhiran, James E.; Bailey, Dalan; Lambe, Teresa; Linterman, Michelle A.
Molecular mechanism of Afadin substrate recruitment to the receptor phosphatase PTPRK via its pseudophosphatase domain

Afadin底物通过其假磷酸酶结构域募集到受体磷酸酶PTPRK的分子机制

ELIFE
IF0
2022-10-202
OA
Hay, Iain M.; Mulholland, Katie E.; Lai, Tiffany; Graham, Stephen C.; Sharpe, Hayley J.; Deane, Janet E.
Protein Tyrosine Pseudophosphatase Signalling Mechanisms
FASEB JOURNAL
IF4.2
2022-05-130
PRE
Sharpe, Hayley J.; Hay, Iain M.; Deane, Janet E.
Mutations in phospholipase C eta-1 (PLCH1) are associated with holoprosencephaly
JOURNAL OF MEDICAL GENETICS
IF3.7
2021-04-053
OAAI
Drissi, Ichrak; Fletcher, Emily; Shaheen, Ranad; Nahorski, Michael; Alhashem, Amal M.; Lisgo, Steve; Fernandez-Jaen, Alberto; Schon, Katherine; Tlili-Graiess, Kalthoum; Smithson, Sarah F.; Lindsay, Susan; Sharpe, Hayley J.; Alkuraya, Fowzan S.; Woods, Geoff
Protein tyrosine phosphatases in cell adhesion

细胞粘附中的蛋白质酪氨酸磷酸酶

BIOCHEMICAL JOURNAL
IF4.3
2021-03-1026
OAAI
Young, Katherine A.; Biggins, Laura; Sharpe, Hayley J.
The receptor PTPRU is a redox sensitive pseudophosphatase
NATURE COMMUNICATIONS
IF15.7
2020-06-2620
OAAI
Hay, Iain M.; Fearnley, Gareth W.; Rios, Pablo; Koehn, Maja; Sharpe, Hayley J.; Deane, Janet E.
The dead phosphatases society: a review of the emerging roles of pseudophosphatases

死亡磷酸酶协会: 对假磷酸酶的新兴作用的回顾

FEBS JOURNAL
IF4.2
2020-06-1625
OAAI
Reiterer, Veronika; Pawlowski, Krzysztof; Desrochers, Guillaume; Pause, Arnim; Sharpe, Hayley J.; Farhan, Hesso
Vismodegib resistant mutations are not selected in multifocal relapses of locally advanced basal cell carcinoma after vismodegib discontinuation
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
IF8
2019-07-150
PREAI
Ighilahriz, M.; Benfodda, M.; Sharpe, H.; Soufir, N.; Mourah, S.; Dumaz, N.; Battistella, M.; Savina, A.; Bouquet, F.; Nikolaev, S.; Basset-Seguin, N.
The homophilic receptor PTPRK selectively dephosphorylates multiple junctional regulators to promote cell-cell adhesion
ELIFE
IF0
2019-03-2929
OA
Fearnley, Gareth W.; Young, Katherine A.; Edgar, James R.; Antrobus, Robin; Hay, Iain M.; Liang, Wei-Ching; Martinez-Martin, Nadia; Lin, WeiYu; Deane, Janet E.; Sharpe, Hayley J.
Grking the Smoothened signal
SCIENCE SIGNALING
IF6.6
2018-02-064
OAAI
Sharpe, Hayley J.; de Sauvage, Frederic J.
A new trick for an old lipid
eLife
IF0
2016-11-250
OAAI
Sharpe, Hayley
Regulation of the oncoprotein Smoothened by small molecules
NATURE CHEMICAL BIOLOGY
IF13.7
2015-03-18114
PREAI
Sharpe, Hayley J.; Wang, Weiru; Hannoush, Rami N.; de Sauvage, Frederic J.
Efficacy of Hedgehog Pathway Inhibitors in Basal Cell Carcinoma
MOLECULAR CANCER THERAPEUTICS
IF5.5
2015-03-0959
PREAI
Basset-Seguin, Nicole; Sharpe, Hayley J.; de Sauvage, Frederic J.

研究方向

暂未获取到该数据
I
Iain M. Hay
H 指数:5论文数:17被引数:211
F
Frédéric J. de Sauvage
H 指数:103论文数:302被引数:4.8万
J
Janet E. Deane
H 指数:29论文数:115被引数:2,792
M
Michelle A. Linterman
H 指数:47论文数:165被引数:1.1万
W
William S. Foster
H 指数:10论文数:40被引数:500
K
Katherine A. Young
H 指数:18论文数:67被引数:1,043
T
Tiffany Lai
H 指数:2论文数:12被引数:79
G
Gareth W. Fearnley
H 指数:13论文数:25被引数:583
L
Leila Godfrey
H 指数:13论文数:32被引数:1,052
S
Silvia Innocentin
H 指数:22论文数:48被引数:2,298