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Susumu Uchiyama

The University of Osaka

53H指数
658论文数
1.2W被引数
收录论文 163
发表时间
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Differentiation of protein aggregates and silicone oil droplets by fluctuation in scattering amplitude using three-dimensional homodyne light detection通过三维同轴光检测散射振幅波动来区分蛋白质聚集物和硅油液滴
errJournal of Pharmaceutical Sciences
IF3.8
err2026-10-04
err0
PREAI
errKentaro Osawa; Hiroyuki Minemura; Risa Shibuya; Tetsuo Torisu; Susumu Uchiyama
err分享
err收藏
Detection of weak metal ion binding to cutinase-like enzyme using native mass spectrometry and electron spin resonance spectroscopy利用原位质谱和电子自旋共振光谱检测类 cutinase 酶与弱金属离子的结合
errBiochimica et Biophysica Acta-Proteins and Proteomics
IF2.3
err2026-09-28
err0
PREAI
errHaruka Kawase; Fumiya Kondo; Atsuji Kodama; Ko Furukawa; Susumu Uchiyama; Masayuki Oda
err分享
err收藏
Molecular determinants of protein foamability and foam stability revealed by hydrogen/deuterium exchange MALDI mass spectrometry通过氢/氘交换MALDI质谱法揭示的蛋白质发泡能力和泡沫稳定性的分子决定因素
errFood Research International
IF8
err2026-08-18
err0
errOAAI
errTetsuo Torisu; Moe Konishi; Susumu Uchiyama
err分享
err收藏
Dynamic Organizational Strategies of Multidomain Glycosyltransferases Revealed by High-Speed AFM and Solution Biophysics多域糖基转移酶的动态组织策略由高速AFM和溶液生物物理学揭示
errInternational Journal of Molecular Sciences
IF4.9
err2026-08-12
err0
errOAAI
errHirokazu Yagi; You-Rong Lin; Yui Kanaoka; Fumiko Umezawa; Akemi Kim; Kotaro Tomuro; Ken Morishima; Atsuji Kodama; Kentaro Ishii; Susumu Uchiyama; Tadashi Satoh; Masaaki Sugiyama; Takayuki Uchihashi; Koichi Kato
err分享
err收藏
Effect of surfactants on agitation-induced submicron and subvisible particles of therapeutic proteins表面活性剂对搅拌诱导的治疗蛋白亚微米和亚可见粒子的影响
errJournal of Pharmaceutical Sciences
IF3.8
err2026-06-17
err0
PREAI
errKosei Shibata; Arni Gambe-Gilbuena; Kimitoshi Takeda; Kentaro Osawa; Susumu Uchiyama; Takaaki Kurinomaru
err分享
err收藏
A system of paired polyether epoxide hydrolases enables a mouldable enzyme for consecutive ring cyclization cascades成对的聚醚环氧化物水解酶系统使可模制的酶能够进行连续的环环化级联反应
errNature Chemistry
IF20.2
err2026-04-16
err0
PREAI
errNana Yabuno; Atsushi Minami; Taro Ozaki; Yuki Owada; Kohei Sawada; Ayaka Arai; Shusuke Sato; Aoi Sugiyama; Takashi Tadokoro; Tomoyasu Aizawa; Takuya Dosen; Tomo Nomai; Takanori Matsumaru; Junyang Liu; Tao Ye; Atsuji Kodama; Susumu Uchiyama; Kowit Hengphasatporn; Yasuteru Shigeta; Tomohide Saio; Katsumi Maenaka; Min Yao; Hiroyuki Kumeta; Hideaki Oikawa; Toyoyuki Ose
err分享
err收藏
Identification of Recombinant Adeno-Associated Virus Serotypes by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry通过基质辅助激光解吸/电离质谱法鉴定重组腺相关病毒血清型
errAnalytical Chemistry
IF6.7
err2026-03-01
err0
errOAAI
errRyoji Nakatsuka; Kenjiro Matsumoto; Yannan Liu; Kimitoshi Takeda; Yasuo Tsunaka; Tetsuo Torisu; Yuki Yamaguchi; Susumu Uchiyama
err分享
err收藏
Shear flow during reciprocal shaking does not disrupt protein films at the solid–liquid interface往复摇动过程中的剪切流不会破坏固液界面处的蛋白质薄膜
errInternational Journal of Pharmaceutics
IF5.2
err2026-02-28
err0
errOAAI
errTetsuo Torisu; Nana Iwamoto; Rio Okada; Naohiro Degura; Susumu Uchiyama; Nozomu Osaka; Shota Kukimoto; Daiki Watanabe; Yutaro Motoori; Susumu Goto
err分享
err收藏
Quantitative Analysis and Predictive Modeling of Nonspecific Adsorption of Recombinant Adeno-Associated Virus onto Solid Surfaces重组腺相关病毒在固体表面非特异性吸附的定量分析与预测建模
errLangmuir
IF3.9
err2026-02-27
err0
errOAAI
errYuki Ueda; Risa Shibuya; Koichi Shibata; Airi Murai; Yasuo Tsunaka; Mitsuko Fukuhara; Susumu Uchiyama
err分享
err收藏
Flow imaging for particle characterization and quantification in biologicals: A perspective from the Japanese Biopharmaceutical Consortium流式成像在生物制品中颗粒表征与定量分析的应用：日本生物制药协会的视角
errJournal of Pharmaceutical Sciences
IF3.8
err2026-02-26
err0
PREAI
errHiroko Shibata; Tim Menzen; Andrea Hawe; Yu Hayashi; Elena Krayukhina; Masato Kiyoshi; Maho Sakurai; Hirokazu Kito; Hiroyuki Suetomo; Kazue Inaba; Tetsuo Torisu; Susumu Uchiyama; Akiko Ishii-Watabe
err分享
err收藏
Key Role of Pro230 in the Hinge Region on the Architecture and Function of IgG1
errJournal of Medicinal Chemistry
IF6.8
err2026-01-29
err0
errOAAI
errYuuki Koseki; Yuki Yamaguchi; Michihiko Aoyama; Kentaro Hiraka; Minoru Tada; Atsuji Kodama; Akinobu Senoo; Akiko Ishii-Watabe; Takayuki Uchihashi; Kazuyoshi Murata; Susumu Uchiyama; Koichi Kato; Saeko Yanaka; Jose M.M. Caaveiro
err分享
err收藏
Experimental determination of extinction coefficients by sedimentation velocity analytical ultracentrifugation for accurate quantification of recombinant adeno-associated virus通过沉降速度分析超速离心法实验测定消光系数，以实现重组腺相关病毒的准确定量
errJournal of Pharmaceutical Sciences
IF3.8
err2026-01-01
err0
errOAAI
errYamaguchi, Yuki; Maruno, Takahiro; Kurinomaru, Takaaki; Shibuya, Risa; Fukuhara, Mitsuko; Tsunaka, Yasuo; Uchiyama, Susumu
err分享
err收藏
Engineered coagulation factor VIII with enhanced secretion and coagulation potential for hemophilia A gene therapy具有增强分泌和凝血功能的工程化凝血因子VIII，用于血友病A基因治疗
errBlood
IF23.1
err2025-11-10
err0
errOAAI
errYuji Kashiwakura; Yuto Nakajima; Kio Horinaka; Tiago J.S. Lopes; Yuma Furuta; Yuki Yamaguchi; Nemekhbayar Baatartsogt; Morisada Hayakawa; Yuko Katakai; Susumu Uchiyama; Osamu Nureki; Keiji Nogami; Tsukasa Ohmori
err分享
err收藏
Effect of temperature on the aggregation of an Fc-fusion protein under agitation温度对搅拌条件下Fc融合蛋白聚集的影响
errEuropean Journal of Pharmaceutical Sciences
IF4.7
err2025-10-10
err0
errOAAI
errZekun Wang; Arni Gambe-Gilbuena; Satoru Unzai; Susumu Uchiyama; Tetsuo Torisu
err分享
err收藏
Molecular basis of IFN-γ-induced STAT3 phosphorylation stimulated by Sendai virus C proteinIFN-γ诱导的STAT3磷酸化的分子机制，该机制由仙台病毒C蛋白刺激引发
errJournal of Biological Chemistry
IF3.9
err2025-09-18
err0
errOAAI
errKosuke Oda; Yuta Hatori; Atsuji Kodama; Susumu Uchiyama; Takashi Oda; Yasuyuki Matoba; Ami Nakano; Kanako Ninomiya; Seira Yoshidomi; Takemasa Sakaguchi
err分享
err收藏
Variation of VP2 stoichiometry and deamidation of VP1 during production and their impacts on the transduction efficiency of AAV vectorsVP2化学计量比的变化和VP1的脱酰胺化在产生过程中的变化及其对AAV载体转导效率的影响
errMolecular Therapy Methods & Clinical Development
IF4.7
err2025-09-01
err0
errOAAI
errTakahiro Maruno; Mitsuko Fukuhara; Yasuo Tsunaka; Aoba Matsushita; Kiichi Hirohata; Karin Bandoh; Megumi Onaka; Risa Shibuya; Yuki Yamaguchi; Haruka Nishiumi; Yoshiki Nagashima; Daisuke Higo; Toshie Kuwahara; Tomoko Ueno; Masaharu Maeda; Guirong Kanai-Bai; Noriko Yamano-Adachi; Tetsuo Torisu; Takeshi Omasa; Susumu Uchiyama
err分享
err收藏
Analytical dissection of minor glycoforms and glycoprotein associations in rAAV preparations by multimodal glycoproteomics通过多模式糖组学对rAAV制剂中的次要糖型及糖蛋白关联进行解析
errAnalytical and Bioanalytical Chemistry
IF3.8
err2025-08-07
err0
PREAI
errAtsushi Kuno; Hiroaki Sakaue; Sachiko Koizumi; Azusa Tomioka; Saho Mizukado; Yuki Yamaguchi; Mitsuko Fukuhara; Yasuo Tsunaka; Hiroyuki Kaji; Susumu Uchiyama
err分享
err收藏
Unfolding of viral protein 1 N-termini facilitates genome ejection from recombinant adeno-associated virus serotype 8重组腺相关病毒血清型8中，病毒蛋白1的N端展开促进了基因组排出。
errMOLECULAR THERAPY METHODS & CLINICAL DEVELOPMENT
IF4.7
err2025-06-01
err0
errOAAI
errYuki Yamaguchi; Saki Shimojo; Tomohiko Ikeda; Mitsuko Fukuhara; Yasuo Tsunaka; Risa Shibuya; Mark Allen Vergara Rocafort; Ryoji Nakatsuka; Kiichi Hirohata; Tetsuo Torisu; Susumu Uchiyama
err分享
err收藏
Hierarchical clustering of therapeutic proteins based on agitation-induced aggregation propensity and its relation to physicochemical parameters
errEUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
IF4.7
err2025-05-01
err0
PREAI
errOkada, Rio; Shibata, Kosei; Shibuya, Risa; Torisu, Tetsuo; Uchiyama, Susumu
err分享
err收藏
Survey and Establishment of Points to Consider for Application of Analytical Techniques to Evaluate Protein Aggregates and Insoluble Particles in Biopharmaceuticals: Experiences in Japan Biopharmaceutical Consortium生物制药中应用分析技术评估蛋白质聚集物和不溶性微粒的注意事项调查与建立：日本生物制药协会的经验
errAAPS JOURNAL
IF3.7
err2025-04-03
err0
errOAAI
errShibata, H; Saitoh, S; Kiyoshi, M; Hayashi, Y; Inaba, K; Katsura, S; Sakurai, M; Komine, Y; Okabe, S; Ohbayashi, N; Kita, Y; Kito, H; Nakano, M; Miyamoto, K; Maruyama, A; Miyahara, Y; Noda, M; Nozawa, Y; Shimbo, K; Kojima, S; Honda, S; Torisu, T; Uchiyama, S; Ishii-Watabe, A
err分享
err收藏

研究方向

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