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M

Mathieu J. F. Crupi

University of Ottawa
H指数:16
被引数:742

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Complementary dual-virus strategy drives synthetic target and cognate T-cell engager expression for endogenous-antigen agnostic immunotherapy
NATURE COMMUNICATIONS
IF15.7
2024-08-230
OAAI
Taha, Zaid; Crupi, Mathieu Joseph Francois; Alluqmani, Nouf; Mackenzie, Duncan; Vallati, Sydney; Whelan, Jack Timothy; Fareez, Faiha; Alwithenani, Akram; Petryk, Julia; Chen, Andrew; Spinelli, Marcus Mathew; Ng, Kristy; Sobh, Judy; de Souza, Christiano Tanese; Bharadwa, Priya Rose; Lee, Timothy Kit Hin; Thomas, Dylan Anthony; Huang, Ben Zhen; Kassas, Omar; Poutou, Joanna; Gilchrist, Victoria Heather; Boulton, Stephen; Thomson, Max; Marius, Ricardo; Hooshyar, Mohsen; Mccomb, Scott; Arulanandam, Rozanne; Ilkow, Carolina Solange; Bell, John Cameron; Diallo, Jean-Simon
PD-L1 promotes oncolytic virus infection via a metabolic shift that inhibits the type I IFN pathway
JOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
2024-06-131
PRE
Hodgins, Jonathan J.; Abou-Hamad, John; O'Dwyer, Colin Edward; Hagerman, Ash; Yakubovich, Edward; Tanese de Souza, Christiano; Marotel, Marie; Buchler, Ariel; Fadel, Saleh; Park, Maria M.; Fong-McMaster, Claire; Crupi, Mathieu F.; Makinson, Olivia Joan; Kurdieh, Reem; Rezaei, Reza; Dhillon, Harkirat Singh; Ilkow, Carolina S.; Bell, John C.; Harper, Mary-Ellen; Rotstein, Benjamin H.; Auer, Rebecca C.; Vanderhyden, Barbara C.; Sabourin, Luc A.; Bourgeois-Daigneault, Marie-Claude; Cook, David P.; Ardolino, Michele
Inhibition of exchange proteins directly activated by cAMP as a strategy for broad-spectrum antiviral development
JOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
2023-06-010
OAAI
Boulton, Stephen; Crupi, Mathieu J. F.; Singh, Siddharth; Carter-Timofte, Madalina E.; Azad, Taha; Organ, Bailey C.; He, Xiaohong; Gill, Rida; Neault, Serge; Jamieson, Taylor; Dave, Jaahnavi; Kurmasheva, Naziia; Austin, Bradley; Petryk, Julia; Singaravelu, Ragunath; Huang, Ben Zhen; Franco, Noah; Babu, Kaaviya; Parks, Robin J.; Ilkow, Carolina S.; Olagnier, David; Bell, John C.
Synthetic virology approaches to improve the safety and efficacy of oncolytic virus therapies
NATURE COMMUNICATIONS
IF15.7
2023-05-2618
OAAI
Azad, Taha; Rezaei, Reza; Singaravelu, Ragunath; Pelin, Adrian; Boulton, Stephen; Petryk, Julia; Onsu, Kemal Alper; Martin, Nikolas T.; Hoskin, Victoria; Ghahremani, Mina; Marotel, Marie; Marius, Ricardo; He, Xiaohong; Crupi, Mathieu J. F.; Hoang, Huy-Dung; Nik-Akhtar, Abolfazl; Ahmadi, Mahsa; Zamani, Nika Kooshki; Golshani, Ashkan; Alain, Tommy; Greer, Peter; Ardolino, Michele; Dickinson, Bryan C.; Tai, Lee-Hwa; Ilkow, Carolina S.; Bell, John C.
Engineering Rapalog-Inducible Genetic Switches Based on Split-T7 Polymerase to Regulate Oncolytic Virus-Driven Production of Tumour-Localized IL-12 for Anti-Cancer Immunotherapy
PHARMACEUTICALS
IF4.8
2023-05-076
OAAI
Martin, Nikolas T.; Crupi, Mathieu J. F.; Taha, Zaid; Poutou, Joanna; Whelan, Jack T.; Vallati, Sydney; Petryk, Julia; Marius, Ricardo; Austin, Bradley; Azad, Taha; Boulanger, Mason; Burgess, Tamara; Sanders, Ilson; Victoor, Camille; Dickinson, Bryan C.; Diallo, Jean-Simon; Ilkow, Carolina S.; Bell, John C.
Fatty acid transport protein inhibition sensitizes breast and ovarian cancers to oncolytic virus therapy via lipid modulation of the tumor microenvironment
FRONTIERS IN IMMUNOLOGY
IF5.9
2023-03-104
OAAI
Surendran, Abera; Jamalkhah, Monire; Poutou, Joanna; Birtch, Rayanna; Lawson, Christine; Dave, Jaahnavi; Crupi, Mathieu J. F.; Mayer, Justin; Taylor, Victoria; Petryk, Julia; de Souza, Christiano Tanese; Moodie, Neil; Billingsley, Jacob Lecompte; Austin, Bradley; Cormack, Nicole; Blamey, Natalie; Rezaei, Reza; McCloskey, Curtis W.; Fekete, Emily E. F.; Birdi, Harsimrat K.; Neault, Serge; Jamieson, Taylor R.; Wylie, Brenna; Tucker, Sarah; Azad, Taha; Vanderhyden, Barbara; Tai, Lee-Hwa; Bell, John C.; Ilkow, Carolina S.
CRISPR-mediated rapid arming of poxvirus vectors enables facile generation of the novel immunotherapeutic STINGPOX
FRONTIERS IN IMMUNOLOGY
IF5.9
2023-01-136
OAAI
Whelan, Jack T.; Singaravelu, Ragunath; Wang, Fuan; Pelin, Adrian; Tamming, Levi A.; Pugliese, Giuseppe; Martin, Nikolas T.; Crupi, Mathieu J. F.; Petryk, Julia; Austin, Bradley; He, Xiaohong; Marius, Ricardo; Duong, Jessie; Jones, Carter; Fekete, Emily E. F.; Alluqmani, Nouf; Chen, Andrew; Boulton, Stephen; Huh, Michael S.; Tang, Matt Y.; Taha, Zaid; Scut, Elena; Diallo, Jean-Simon; Azad, Taha; Lichty, Brian D.; Ilkow, Carolina S.; Bell, John C.
Oncolytic virus driven T-cell-based combination immunotherapy platform for colorectal cancer
FRONTIERS IN IMMUNOLOGY
IF5.9
2022-11-0319
OAAI
Crupi, Mathieu J. F.; Taha, Zaid; Janssen, Thijs J. A.; Petryk, Julia; Boulton, Stephen; Alluqmani, Nouf; Jirovec, Anna; Kassas, Omar; Khan, Sarwat T.; Vallati, Sydney; Lee, Emily; Huang, Ben Zhen; Huh, Michael; Pikor, Larissa; He, Xiaohong; Marius, Ricardo; Austin, Bradley; Duong, Jessie; Pelin, Adrian; Neault, Serge; Azad, Taha; Breitbach, Caroline J.; Stojdl, David F.; Burgess, Michael F.; McComb, Scott; Auer, Rebecca; Diallo, Jean-Simon; Ilkow, Carolina S.; Bell, John Cameron
Identification of FDA-approved bifonazole as a SARS-CoV-2 blocking agent following a bioreporter drug screen

在生物反应器药物筛选后鉴定FDA批准的联苯苄唑作为SARS-CoV-2阻断剂

MOLECULAR THERAPY
IF12
2022-09-016
OAAI
Taha, Zaid; Arulanandam, Rozanne; Maznyi, Glib; Godbout, Elena; Carter-Timofte, Madalina E.; Kurmasheva, Naziia; Reinert, Line S.; Chen, Andrew; Crupi, Mathieu J. F.; Boulton, Stephen; Laroche, Genevieve; Phan, Alexandra; Rezaei, Reza; Alluqmani, Nouf; Jirovec, Anna; Acal, Alexandra; Fekete, Emily E. F.; Singaravelu, Ragunath; Petryk, Julia; Idorn, Manja; Potts, Kyle G.; Todesco, Hayley; John, Cini; Mahoney, Douglas J.; Ilkow, Carolina S.; Giguere, Patrick; Alain, Tommy; Cote, Marceline; Paludan, Soren R.; Olagnier, David; Bell, John C.; Azad, Taha; Diallo, Jean-Simon
Single-dose replicating poxvirus vector-based RBD vaccine drives robust humoral and T cell immune response against SARS-CoV-2 infection
MOLECULAR THERAPY
IF12
2022-05-0119
OAAI
Boulton, Stephen; Poutou, Joanna; Martin, Nikolas T.; Azad, Taha; Singaravelu, Ragunath; Crupi, Mathieu J. F.; Jamieson, Taylor; He, Xiaohong; Marius, Ricardo; Petryk, Julia; de Souza, Christiano Tanese; Austin, Bradley; Taha, Zaid; Whelan, Jack; Khan, Sarwat T.; Pelin, Adrian; Rezaei, Reza; Surendran, Abera; Tucker, Sarah; Fekete, Emily E. F.; Dave, Jaahnavi; Diallo, Jean-Simon; Auer, Rebecca; Angel, Jonathan B.; Cameron, D. William; Cailhier, Jean-Francois; Lapointe, Rejean; Potts, Kyle; Mahoney, Douglas J.; Bell, John C.; Ilkow, Carolina S.
Virally programmed extracellular vesicles sensitize cancer cells to oncolytic virus and small molecule therapy

病毒程序化的细胞外囊泡使癌细胞对溶瘤病毒和小分子疗法敏感

NATURE COMMUNICATIONS
IF15.7
2022-04-0730
OAAI
Wedge, Marie-Eve; Jennings, Victoria A.; Crupi, Mathieu J. F.; Poutou, Joanna; Jamieson, Taylor; Pelin, Adrian; Pugliese, Giuseppe; de Souza, Christiano Tanese; Petryk, Julia; Laight, Brian J.; Boileau, Meaghan; Taha, Zaid; Alluqmani, Nouf; McKay, Hayley E.; Pikor, Larissa; Khan, Sarwat Tahsin; Azad, Taha; Rezaei, Reza; Austin, Bradley; He, Xiaohong; Mansfield, David; Rose, Elaine; Brown, Emily E. F.; Crawford, Natalie; Alkayyal, Almohanad; Surendran, Abera; Singaravelu, Ragunath; Roy, Dominic G.; Migneco, Gemma; McSweeney, Benjamin; Cottee, Mary Lynn; Jacobus, Egon J.; Keller, Brian A.; Yamaguchi, Takafumi N.; Boutros, Paul C.; Geoffrion, Michele; Rayner, Katey J.; Chatterjee, Avijit; Auer, Rebecca C.; Diallo, Jean-Simon; Gibbings, Derrick; tenOever, Benjamin R.; Melcher, Alan; Bell, John C.; Ilkow, Carolina S.
Nanoluciferase complementation-based bioreporter reveals the importance of N-linked glycosylation of SARS-CoV-2 S for viral entry
MOLECULAR THERAPY
IF12
2021-06-0122
OAAI
Azad, Taha; Singaravelu, Ragunath; Taha, Zaid; Jamieson, Taylor R.; Boulton, Stephen; Crupi, Mathieu J. F.; Martin, Nikolas T.; Fekete, Emily E. F.; Poutou, Joanna; Ghahremani, Mina; Pelin, Adrian; Nouri, Kazem; Rezaei, Reza; Marshall, Christopher Boyd; Enomoto, Masahiro; Arulanandam, Rozanne; Alluqmani, Nouf; Samson, Reuben; Gingras, Anne-Claude; Cameron, D. William; Greer, Peter A.; Ilkow, Carolina S.; Diallo, Jean-Simon; Bell, John C.
Implications for SARS-CoV-2 Vaccine Design: Fusion of Spike Glycoprotein Transmembrane Domain to Receptor-Binding Domain Induces Trimerization

SARS-CoV-2疫苗设计的意义: 刺突糖蛋白跨膜结构域与受体结合结构域的融合诱导三聚化

MEMBRANES
IF3.6
2020-08-3020
OAAI
Azad, Taha; Singaravelu, Ragunath; Crupi, Mathieu J. F.; Jamieson, Taylor; Dave, Jaahnavi; Brown, Emily E. F.; Rezaei, Reza; Taha, Zaid; Boulton, Stephen; Martin, Nikolas T.; Surendran, Abera; Poutou, Joanna; Ghahremani, Mina; Nouri, Kazem; Whelan, Jack T.; Duong, Jessie; Tucker, Sarah; Diallo, Jean-Simon; Bell, John C.; Ilkow, Carolina S.

研究方向

暂未获取到该数据
C
Carolina S. Ilkow
H 指数:24论文数:93被引数:2,332
J
John C. Bell
H 指数:84论文数:453被引数:3.0万
J
Jean‐Simon Diallo
H 指数:35论文数:164被引数:4,964
T
Taha Azad
H 指数:22论文数:77被引数:1,673
R
Ragunath Singaravelu
H 指数:25论文数:53被引数:1,740
R
Reza Rezaei
H 指数:21论文数:83被引数:1,534
Z
Zaid Taha
H 指数:12论文数:34被引数:530
J
Julia Petryk
H 指数:12论文数:60被引数:399
L
Lois M. Mulligan
H 指数:47论文数:223被引数:1.1万
S
Stephen Boulton
H 指数:20论文数:48被引数:1,113