Diego A. Oyarzún - Publications, H-index & Citations

Diego A. Oyarzún

University of Edinburgh

28H指数

138论文数

2.9K被引数

收录论文 41

发表时间

A comprehensive pharmacological survey across heterogeneous patient-derived glioblastoma stem cell models 异质性患者源性胶质母细胞瘤干细胞模型的全面药理学调查

iScience

IF4.1

2026-04-27

OAAI

Richard J.R. Elliott; Peter W.K. Nagle; Muhammad Furqan; John C. Dawson; Vanessa Smer-Barreto; Diego A. Oyarzún; Aoife McCarthy; Alison F. Munro; Camilla Drake; Gillian M. Morrison; Steven M. Pollard; Michael Marand; Daniel Ebner; Valerie G. Brunton; Margaret C. Frame; Neil O. Carragher

Signatures of Electron–Hole Hopping in Myoglobin Peroxidase Activity Revealed by Deep Mutational Learning 电子-空穴跳跃在肌红蛋白过氧化物酶活性中的特征，由深度突变学习揭示

ACS Catalysis

IF13.1

2026-03-13

PREAI

Christoph Küng; Alperen Dalkıran; Rosario Vanella; Diego A. Oyarzún; Michael A. Nash

Optimization of regulatory DNA with active learning 基于主动学习的调控DNA优化

Computational and Structural Biotechnology Journal

IF4.1

2025-10-04

OAAI

Yuxin Shen; Grzegorz Kudla; Diego A. Oyarzún

Modeling host–pathway dynamics at the genome scale with machine learning 利用机器学习在基因组规模上模拟宿主-通路动态

Metabolic Engineering

IF6.8

2025-06-17

OAAI

Charlotte Merzbacher; Oisin Mac Aodha; Diego A. Oyarzún

Can protein expression be ‘solved’?Baranowski, C.; Martin, H.G.; Oyarzún, D.A.; Spinner, A.; Desai, B.; Petzold, C.J.; Nikolados, E.M.; Jaaks-Kraatz, S.; Scannell, D.; Sevey, R.; et al. 蛋白质表达能被“解决”吗？Trends Biotechnol. 2025. [Google Scholar] [CrossRef] [PubMed]

Trends in Biotechnology

IF14.9

2025-06-02

OAAI

Catherine Baranowski; Hector Garcia Martin; Diego A. Oyarzún; Aviv Spinner; Bijoy Desai; Christopher J. Petzold; Evangelos-Marios Nikolados; Sebastian Jaaks-Kraatz; Aljaž Gaber; Robert J. Chalkley; Devin Scannell; Rachel Sevey; Michael C. Jewett; Peter J. Kelly; Erika A. DeBenedictis

Tuning ProteinMPNN to reduce protein visibility via MHC Class I through direct preference optimization 通过直接偏好优化调整ProteinMPNN，以减少通过MHC Class I的蛋白质可见性

PROTEIN ENGINEERING DESIGN & SELECTION

IF3.4

2025-03-18

PREAI

Gasser, Hans-Christof; Oyarzun, Diego A.; Alfaro, Javier Antonio; Rajan, Ajitha

Multiscale modelling of bioprocess dynamics and cellular growth

MICROBIAL CELL FACTORIES

IF4.9

2024-11-22

OAAI

Mahnert, Camilo; Oyarzun, Diego A.; Berrios, Julio

A call for caution when using network methods to study multimorbidity: an illustration using data from the Canadian Longitudinal Study on Aging

JOURNAL OF CLINICAL EPIDEMIOLOGY

IF5.2

2024-08-01

PREAI

Griffith, Lauren E.; Brini, Alberto; Muniz-Terrera, Graciela; St John, Philip D.; Stirland, Lucy E.; Mayhew, Alexandra; Oyarzun, Diego; van den Heuvel, Edwin

Integration of graph neural networks and genome-scale metabolic models for predicting gene essentiality

NPJ SYSTEMS BIOLOGY AND APPLICATIONS

IF3.5

2024-03-06

OAAI

Hasibi, Ramin; Michoel, Tom; Oyarzun, Diego A.

Applications of artificial intelligence and machine learning in dynamic pathway engineering

BIOCHEMICAL SOCIETY TRANSACTIONS

IF4.3

2023-09-01

OAAI

Merzbacher, Charlotte; Oyarzun, Diego A.

Bayesian Optimization for Design of Multiscale Biological Circuits 多尺度生物电路设计的贝叶斯优化

ACS SYNTHETIC BIOLOGY

IF3.9

2023-06-20

OAAI

Merzbacher, Charlotte; Mac Aodha, Oisin; Oyarzun, Diego A.

Discovery of senolytics using machine learning 使用机器学习发现senolyics

NATURE COMMUNICATIONS

IF15.7

2023-06-10

OAAI

Smer-Barreto, Vanessa; Quintanilla, Andrea; Elliott, Richard J. R.; Dawson, John C.; Sun, Jiugeng; Campa, Victor M.; Lorente-Macias, Alvaro; Unciti-Broceta, Asier; Carragher, Neil O.; Acosta, Juan Carlos; Oyarzun, Diego A.

Deep learning for optimization of protein expression

CURRENT OPINION IN BIOTECHNOLOGY

IF7

2023-06-01

OAAI

Nikolados, Evangelos-Marios; Oyarzun, Diego A.

P1 Bacteriophage-Enabled Delivery of CRISPR-Cas9 Antimicrobial Activity Against Shigella flexneri P1噬菌体能够传递对福氏志贺氏菌的CRISPR-Cas9抗菌活性

ACS SYNTHETIC BIOLOGY

IF3.9

2023-02-20

OAAI

Huan, Yang W.; Torraca, Vincenzo; Brown, Russell; Fa-arun, Jidapha; Miles, Sydney L.; Oyarzun, Diego A.; Mostowy, Serge; Wang, Baojun

Accuracy and data efficiency in deep learning models of protein expression

NATURE COMMUNICATIONS

IF15.7

2022-12-15

OAAI

Nikolados, Evangelos-Marios; Wongprommoon, Arin; Aodha, Oisin Mac; Cambray, Guillaume; Oyarzun, Diego A.

Microbial polysaccharides: An emerging family of natural biomaterials for cancer therapy and diagnostics 微生物多糖: 用于癌症治疗和诊断的新兴天然生物材料家族

SEMINARS IN CANCER BIOLOGY

IF15.7

2022-11-01

OAAI

Prateeksha; Sharma, Vivek K.; Liu, Xiaowen; Oyarzun, Diego A.; Abdel-Azeem, Ahmed M.; Atanasov, Atanas G.; Hesham, Abd El-Latif; Barik, Saroj K.; Gupta, Vijai Kumar; Singh, Brahma N.

Integrated methylome and phenome study of the circulating proteome reveals markers pertinent to brain health

NATURE COMMUNICATIONS

IF15.7

2022-08-09

OAAI

Gadd, Danni A.; Hillary, Robert F.; McCartney, Daniel L.; Shi, Liu; Stolicyn, Aleks; Robertson, Neil A.; Walker, Rosie M.; McGeachan, Robert, I; Campbell, Archie; Xueyi, Shen; Barbu, Miruna C.; Green, Claire; Morris, Stewart W.; Harris, Mathew A.; Backhouse, Ellen, V; Wardlaw, Joanna M.; Steele, J. Douglas; Oyarzun, Diego A.; Muniz-Terrera, Graciela; Ritchie, Craig; Nevado-Holgado, Alejo; Chandra, Tamir; Hayward, Caroline; Evans, Kathryn L.; Porteous, David J.; Cox, Simon R.; Whalley, Heather C.; McIntosh, Andrew M.; Marioni, Riccardo E.

Stabilization of antithetic control via molecular buffering

JOURNAL OF THE ROYAL SOCIETY INTERFACE

IF3.5

2022-03-09

OAAI

Hancock, Edward J.; Oyarzun, Diego A.

Trade-Offs in Biosensor Optimization for Dynamic Pathway Engineering 动态途径工程的生物传感器优化中的权衡

ACS SYNTHETIC BIOLOGY

IF3.9

2021-12-30

OAAI

Verma, Babita K.; Mannan, Ahmad A.; Zhang, Fuzhong; Oyarzun, Diego A.

Systems level profiling of chemotherapy-induced stress resolution in cancer cells reveals druggable trade-offs

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-04-21

OAAI

Saavedra-Garcia, Paula; Roman-Trufero, Monica; Al-Sadah, Hibah A.; Blighe, Kevin; Lopez-Jimenez, Elena; Christoforou, Marilena; Penfold, Lucy; Capece, Daria; Xiong, Xiaobei; Miao, Yirun; Parzych, Katarzyna; Caputo, Valentina S.; Siskos, Alexandros P.; Encheva, Vesela; Liu, Zijing; Thiel, Denise; Kaiser, Martin F.; Piazza, Paolo; Chaidos, Aristeidis; Karadimitris, Anastasios; Franzoso, Guido; Snijders, Ambrosius P.; Keun, Hector C.; Oyarzun, Diego A.; Barahona, Mauricio; Auner, Holger W.

研究方向