Barbara S. Slusher - Publications, H-index & Citations

Barbara S. Slusher

johns hopkins university

67H指数

584论文数

2.1W被引数

收录论文 228

发表时间

Sex-specific gut mycobiome dysbiosis activates macrophage dectin-1 signaling to drive neurobehavioral deficits in EcoHIV-infected mice 性别特异的肠道真菌菌群失调可激活巨噬细胞Dectin-1信号通路，进而驱动EcoHIV感染小鼠的神经行为缺陷。

brain, behavior, and immunity

IF0

2026-03-11

OAAI

Yannan Li; Shinji Sakamoto; Matthew D. Smith; Yuto Hasegawa; Meixiang Huang; Naigang Li; Manjot Dhaliwal; Tessa Schauermann; Feiyi Xiong; Bin Luo; Hui Li; Qingsheng Li; Peter A. Calabresi; David Volsky; Barbara S. Slusher; Atsushi Kamiya; Xiaolei Zhu

A Star-PEGylation Strategy to Improve Testosterone Pharmacokinetics 星状-PEG化策略以改善睾酮药代动力学

Molecules

IF4.6

2026-03-04

OAAI

Chae Bin Lee; Lukáš Tenora; Ruoning Zhang; Arina Ranjit; Mark C. Markowski; Barbara S. Slusher; Rana Rais

N-acetyl-aspartyl-glutamate connects neuroinflammatory signatures to attention and working memory in people with HIV N-乙酰天冬氨酰谷氨酸将神经炎症特征与艾滋病患者的注意力和工作记忆联系起来

AIDS

IF3.1

2026-02-26

PREAI

Rubin, Leah H.a, b, c, d; Chandra, Atiksha; Alt, Jessee; Dastgheyb, Raha M.a; Romero, Hayleyc; Coughlin, Jennifer M.b, f; Rais, Ranaa, e, g, h; Veenhuis, Rebecca T.a, c; Slusher, Barbara S.a, e, g, h, i, j

CRISPR screen of human pancreatic cancer xenografts identifies a KLF5 proliferation vulnerability through epigenetic modifiers NCAPD2 and MTHFD1 人胰腺癌异种移植物的CRISPR筛选通过表观遗传修饰剂NCAPD2和MTHFD1鉴定KLF5增殖脆弱性

Molecular Cancer

IF33.9

2026-02-10

OAAI

Masahiro Maeda; Kenna Sherman; Weiqiang Zhou; Jiaqi Cheng; Yuta Nihongaki; Adrian Idrizi; Rakel Tryggvadottir; Oscar Camacho; Xingbo Shang; Jimin Min; Michael A. Koldobskiy; Anirban Maitra; Andre Levchenko; Barbara S. Slusher; Hongkai Ji; Andrew P. Feinberg

Discovery of N-Acetyltransferase 8-Like (NAT8L) Inhibitors Based on a N-Acylated (Piperidin-3-ylmethyl)-1; 2; 4-Oxadiazole Scaffold

ACS Medicinal Chemistry Letters

IF4

2026-02-03

PREAI

Md Junayed Nayeen; Ajit G. Thomas; Biswajit Kundu; Evan Carlyle; Niyada Hin; Philana Hin; Arindom Pal; James Paule; Rana Rais; Barbara S. Slusher; Takashi Tsukamoto

An orally bioavailable MrgprX1-positive allosteric modulator alleviates certain neuropathic pain-related behaviors in humanized mice

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2025-12-17

PREAI

Uniyal, Ankit; Hin, Niyada; Zhang, Chi; Xu, Qian; Huang, Qian; Berhane, Ilyas; Thomas, Ajit G.; Maragakis, John; Gori, Sadakatali; Liu, Jing; Zheng, Qin; Cui, Xiang; Peng, Qi; Wan, Jieru; Rais, Rana; Slusher, Barbara S.; Raja, Srinivasa. N.; Dong, Xinzhong; Tsukamoto, Takashi; Guan, Yun

Resilient pathways for drug discovery in challenging times 在挑战时期用于药物发现的韧性路径

Trends in Pharmacological Sciences

IF19.9

2025-11-26

PREAI

Sean Ekins; Barbara S. Slusher

Mass spectrometry-guided discovery of novel GCPII inhibitor scaffolds 质谱指导的新型GCPII抑制剂骨架的发现

Frontiers in Pharmacology

IF4.8

2025-10-15

OAAI

Robyn Wiseman; Ajit G. Thomas; John Janiszewski; Nate Hoxie; Chae Bin Lee; Ying Wu; Takashi Tsukamoto; Lin Ye; Michael Ronzetti; Jonathan H. Shrimp; Davina Adderley; Ganesha Rai; Rana Rais; Jesse Alt; Matthew D. Hall; Xin Hu; Stephen C. Kales; Barbara S. Slusher

Inhibition of Glutamine Metabolism Attenuates Tumor Progression Through Remodeling of the Macrophage Immune Microenvironment 通过重塑巨噬细胞免疫微环境，谷氨酰胺代谢的抑制可缓解肿瘤进展。

Advanced Biology

IF2.6

2025-07-13

OAAI

Tianhe Li; Sepehr Akhtarkhavari; Sumeng Qi; Jiawei Fan; Tu-Yung Chang; Yao-An Shen; JinMing Yang; Barbara S. Slusher; Ie-Ming Shih; Stephanie Gaillard; Tian-Li Wang

The potential of academic drug discovery: successes and challenges 学术药物发现的潜力：成功与挑战

Expert Opinion on Drug Discovery

IF4.9

2025-07-02

PREAI

Matthew Stremlau; Barbara S. Slusher

GCPII as a Therapeutic Target for Inflammatory Bowel Disease (IBD): Expression in Human IBD Versus Preclinical Colitis Models GCPII 作为炎症性肠病（IBD）的治疗靶点：在人类 IBD 与预临床结肠炎模型中的表达

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2025-03-01

PREAI

Zhi, Sabrina; Zhang, Sophia; Pradhan, Manisha; Slusher, Barbara; Peters, Diane

TOWARDS DEVELOPMENT OF TARGETED THERAPEUTICS FOR CHRONIC PAIN IN IBD: ANALGESIC EFFICACY OF AN ORAL GCPII INHIBITOR IN PRECLINICAL VISCERAL PAIN MODELS 靶向治疗炎症性肠病慢性疼痛的药物开发：一种口服GCPII抑制剂在临床前内脏疼痛模型中的镇痛疗效

INFLAMMATORY BOWEL DISEASES

IF4.3

2025-02-28

PREAI

Peters, Diane; Liu, Liansheng; Zhi, Sabrina; Pradhan, Manisha; Li, Qian; Pasricha, Pankaj J.; Slusher, Barbara

JHU-2545 preferentially shields salivary glands and kidneys during PSMA-targeted imaging 在PSMA靶向成像期间，JHU-2545优先屏蔽唾液腺和肾脏

European Journal of Nuclear Medicine and Molecular Imaging

IF7.6

2025-01-02

OAAI

Nedelcovych, Michael T.; Dash, Ranjeet P.; Wu, Ying; Choi, Eun Yong; Lapidus, Rena S.; Majer, Pavel; Jancarik, Andrej; Abou, Diane; Penet, Marie-France; Nikolopoulou, Anastasia; Amor-Coarasa, Alex; Babich, John; Thorek, Daniel L.; Rais, Rana; Kratochwil, Clemens; Slusher, Barbara S.

Pharmacokinetic Evaluation of Neutral Sphinghomyelinase2 (nSMase2) Inhibitor Prodrugs in Mice and Dogs 中性鞘氨醇酶2 (nSMase2) 抑制剂前药在小鼠和狗中的药代动力学评价

PHARMACEUTICS

IF5.5

2024-12-26

OAAI

Ranjit, Arina; Lee, Chae Bin; Tenora, Lukas; Mettu, Vijaya Saradhi; Pal, Arindom; Alt, Jesse; Slusher, Barbara S.; Rais, Rana

Aged fibroblast-derived extracellular vesicles promote angiogenesis in melanoma

CELL REPORTS

IF6.9

2024-09-01

OAAI

Hueser, Laura; Chhabra, Yash; Gololobova, Olesia; Wang, Vania; Liu, Guanshu; Dixit, Agrani; Rocha, Murilo Ramos; Harper, Elizabeth I.; Fane, Mitchell E.; Marino-Bravante, Gloria E.; Zabransky, Daniel J.; Cai, Kathy Q.; Utikal, Jochen; Slusher, Barbara S.; Walston, Jeremy; Lipson, Evan J.; Witwer, Kenneth W.; Weeraratna, Ashani T.

Nuclear GAPDH in cortical microglia mediates cellular stress-induced cognitive inflexibility (Jul, 10.1038/s41380-024-02553-1, 2024)

MOLECULAR PSYCHIATRY

IF10.1

2024-07-01

PREAI

Ramos, Adriana; Ishizuka, Koko; Hayashida, Arisa; Namkung, Ho; Hayes, Lindsay N.; Srivastava, Rupali; Zhang, Manling; Kariya, Taro; Elkins, Noah; Palen, Trexy; Carloni, Elisa; Tsujimura, Tsuyoshi; Calva, Coleman; Ikemoto, Satoshi; Rais, Rana; Slusher, Barbara S.; Niwa, Minae; Saito, Atsushi; Saitoh, Toshiaki; Takimoto, Eiki; Sawa, Akira

TARGETING CTPS1 AND NUCLEOTIDE BIOSYNTHESIS PATHWAYS AS A NOVEL THERAPEUTIC APPROACH IN MYC-AMPLIFIED MEDULLOBLASTOMA

NEURO-ONCOLOGY

IF13.4

2024-06-18

OAAI

Hathaway, Matthew; Jagana, Hawa; Terrones, Isabella; Miyaki, Aya; Hemenway, John; Meechan, Michael; Gadek, Kate; Slusher, Barbara; Evans II, Myron

Development of Novel Tools for Dissection of Central Versus Peripheral Dopamine D2-Like Receptor Signaling in Dysglycemia

DIABETES

IF7.5

2024-06-13

OAAI

Bonifazi, Alessandro; Ellenberger, Michael; Farino, Zachary J.; Aslanoglou, Despoina; Rais, Rana; Pereira, Sandra; Mantilla-Rivas, Jose O.; Boateng, Comfort A.; Eshleman, Amy J.; Janowsky, Aaron; Hahn, Margaret K.; Schwartz, Gary J.; Slusher, Barbara S.; Newman, Amy Hauck; Freyberg, Zachary

Nuclear GAPDH in cortical microglia mediates cellular stress-induced cognitive inflexibility

MOLECULAR PSYCHIATRY

IF10.1

2024-04-13

OAAI

Targeting CTPS1 and nucleotide biosynthesis pathways as a novel therapeutic approach in MYC-amplified medulloblastoma

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Hathaway, Matthew; Jagana, Hawa; Meechan, Michael; Hemenway, John; Gadek, Kate E.; Miyaki, Aya; Terrones, Isabella; Slusher, Barbara; Pattwell, Siobhan; Vitanza, Nicholas; Evans, Myron K.

研究方向