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D

Diego Esposito

the francis crick institute

H指数:20

被引数:1,717

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RING E3 ligase TRIM8 is structurally selective for UBE2N-mediated ubiquitination

RING E3连接酶TRIM8在结构上对UBE2N介导的泛素化具有选择性

Journal of Biological Chemistry

IF3.9

2026-10-140

OAAI

Structure and mechanism of the HECT ligase HECTD3

HECT泛素连接酶HECTD3的结构与机制

Nature Communications

IF15.7

2026-02-140

OAAI

Covalent fragment screening to inhibit the E3 ligase activity of bacterial NEL enzymes SspH1 and SspH2

共价片段筛选以抑制细菌NEL酶SspH1和SspH2的E3连接酶活性

RSC Chem. Biol.

IF3.1

2025-10-290

OAAI

Conformational dynamics of the bacterial E3 ligase SspH1

细菌E3连接酶SspH1的构象动力学

Journal of Biological Chemistry

IF3.9

2025-09-010

OAAI

Identification of RING E3 pseudoligases in the TRIM protein family

TRIM蛋白家族中RING E3伪连接酶的鉴定

NATURE COMMUNICATIONS

IF15.7

2025-04-110

OA

Discovery and optimisation of a covalent ligand for TRIM25 and its application to targeted protein ubiquitination

TRIM25共价配体的发现与优化及其在靶向蛋白泛素化中的应用

CHEMICAL SCIENCE

IF7.4

2025-01-010

OA

Divergent self-association properties of paralogous proteins TRIM2 and TRIM3 regulate their E3 ligase activity

NATURE COMMUNICATIONS

IF15.7

2022-12-087

OAAI

Characterisation of HOIP RBR E3 ligase conformational dynamics using integrative modelling

SCIENTIFIC REPORTS

IF3.9

2022-09-082

OAAI

Does it take two to tango? RING domain self-association and activity in TRIM E3 ubiquitin ligases

BIOCHEMICAL SOCIETY TRANSACTIONS

IF4.3

2020-11-1039

OAAI

Characterisation of class VI TRIM RING domains: linking RING activity to C-terminal domain identity

LIFE SCIENCE ALLIANCE

IF2.9

2019-04-2627

OAAI

Structure-function analyses of the bacterial zinc metalloprotease effector protein GtgA uncover key residues required for deactivating NF-B

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2018-09-0131

OAAI

Dynamic Allostery in PLCγ1 and Its Modulation by a Cancer Mutation Revealed by MD Simulation and NMR

BIOPHYSICAL JOURNAL

IF3.1

2018-07-0110

OAAI

Structural basis for the glycosyltransferase activity of the Salmonella effector SseK3

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2018-04-0146

OAAI

Determinants of E2-ubiquitin conjugate recognition by RBR E3 ligases

SCIENTIFIC REPORTS

IF3.9

2018-01-0817

OAAI

Structural determinants of TRIM protein function

BIOCHEMICAL SOCIETY TRANSACTIONS

IF4.3

2017-02-15160

PREAI

Functional role of TRIM E3 ligase oligomerization and regulation of catalytic activity

IF8.3

2016-05-06142

OAAI

Evaluating the conformation of recombinant domain I of β2-glycoprotein I and its interaction with human monoclonal antibodies

MOLECULAR IMMUNOLOGY

IF3

2011-10-0113

OAAI

Rac Regulates Its Effector Phospholipase Cγ2 through Interaction with a Split Pleckstrin Homology Domain

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2008-10-0157

OAAI

Biophysical and cell-based evidence for differential interactions between the death domains of CD95/Fas and FADD

CELL DEATH AND DIFFERENTIATION

IF15.4

2007-06-2913

OAAI

Characterization of a bicyclic peptide neuropilin-1 (NP-1) antagonist (EG3287) reveals importance of vascular endothelial growth factor Exon 8 for NP-1 binding and role of NP-1 in KDR signaling

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2006-05-01144

OAAI