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Patrick Aouad

Discovery Oncology

H指数:11

被引数:436

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Preclinical models of breast cancer metastasis: strengths, limitations, and clinical relevance

乳腺癌转移的术前模型：优势、局限性与临床相关性

npj Breast Cancer

IF7.6

2026-03-140

OAAI

ERα dysfunction caused by ESR1 mutations and therapeutic pressure promotes lineage plasticity in ER+ breast cancer

由ESR1突变和疗法压力导致的ERα功能失调促进了ER阳性乳腺癌的谱系可塑性

IF28.5

2025-01-130

PRE

Transcriptomics-based drug screening in 3D ex vivo patientderived breast cancer model and patient biopsy for personalized therapy

CANCER RESEARCH

IF16.6

2024-05-020

PRE

Epithelial-mesenchymal plasticity determines estrogen receptor positive breast cancer dormancy and epithelial reconversion drives recurrence

上皮-间质可塑性决定雌激素受体阳性乳腺癌休眠和上皮再转换驱动复发

NATURE COMMUNICATIONS

IF15.7

2022-08-2534

OAAI

An engineered multicellular stem cell niche for the 3D derivation of human myogenic progenitors from iPSCs

IF8.3

2022-06-153

OA

Intraductal xenografts show lobular carcinoma cells rely on their own extracellular matrix and LOXL1

EMBO MOLECULAR MEDICINE

IF8.3

2021-02-2234

OAAI

Therapeutic targeting of the pentose phosphate pathway in colorectal cancer

CANCER RESEARCH

IF16.6

2020-08-150

PRE

The secreted protease Adamts18 links hormone action to activation of the mammary stem cell niche

NATURE COMMUNICATIONS

IF15.7

2020-03-2638

OAAI

Intraductal patient-derived xenografts of estrogen receptor α-positive breast cancer recapitulate the histopathological spectrum and metastatic potential of human lesions

JOURNAL OF PATHOLOGY

IF5.2

2018-12-2725

OAAI

Oestrogen receptor α AF-1 and AF-2 domains have cell population-specific functions in the mammary epithelium

NATURE COMMUNICATIONS

IF15.7

2018-11-0929

OAAI

Antitumor Effect of the Atypical Retinoid ST1926 in Acute Myeloid Leukemia and Nanoparticle Formulation Prolongs Lifespan and Reduces Tumor Burden of Xenograft Mice

MOLECULAR CANCER THERAPEUTICS

IF5.5

2017-10-0212

OAAI

Encapsulation of the atypical retinoid ST1926 in nanoparticles prolongs the survival of acute myeloid leukemia xenografted mice at multiple folds lower concentrations than the naked drug

CANCER RESEARCH

IF16.6

2017-07-010

PRE

Combination treatments with retinoic acid and the synthetic retinoid ST1926 in 2D and 3D breast cancer models overcome retinoic acid resistance and eradicate breast cancer stem/progenitor cells

CANCER RESEARCH

IF16.6

2016-07-151

PRE