Gaya K. Amarasinghe - Publications, H-index & Citations

Gaya K. Amarasinghe

washington university

55H指数

181论文数

1.1W被引数

收录论文 80

发表时间

Biochemical basis for LRP1 interaction with Rift Valley fever virus glycoprotein and its role in viral entry LRP1与裂谷热病毒糖蛋白相互作用的生化基础及其在病毒入侵中的作用

Journal of Molecular Biology

IF4.5

2026-06-09

OAAI

Farheen Fatma; David A. Price; Rachael E. Rush; Cadence Allen; Haley Stuckmeyer; Griffin Brown; Thomas J. Brett; Amy L. Hartman; Daisy W. Leung; Gaya K. Amarasinghe

Biophysical characterization of Ebola VP35 protein binding to host Mindbomb protein 2 埃博拉病毒VP35蛋白与宿主Mindbomb蛋白2结合的生物物理表征

Journal of Molecular Biology

IF4.5

2026-05-21

PREAI

Xinyi Cynthia Kuang; Grace Uwase; Nicole D. Wagner; Michael Gross; Daisy W. Leung; Gaya K. Amarasinghe

Multiple LDLR family members act as entry receptors for yellow fever virus 多种LDLR家族成员充当黄热病病毒的进入受体。

Nature

IF48.5

2025-10-29

PREAI

Zhenlu Chong; Sean Hui; Xueer Qiu; Sathvik Palakurty; Alan Sariol; Tomasz Kaszuba; Michael N. Nguyen; Pengfei Li; Saravanan Raju; Paige D. Hall; Christopher A. Nelson; Israel Baltazar-Perez; David A. Price; Paul W. Rothlauf; James E. Crowe; Sean P. J. Whelan; Daisy W. Leung; Gaya K. Amarasinghe; Adam L. Bailey; Daved H. Fremont; Michael S. Diamond

GATA2 mutation is associated with immune dysfunction and increased Mycobacterium haemophilum susceptibility in immunocompromised individuals GATA2基因突变与免疫功能紊乱及免疫抑制个体对嗜血分枝杆菌属（Mycobacterium haemophilum）易感性的增加相关。

JCI INSIGHT

IF6.1

2025-09-23

OAAI

Gupta, Ananya; Mehta, Shail B.; Abhimanyu; Rosa, Bruce A.; Martin, John; Ahmed, Mushtaq; Thirunavukkarasu, Shyamala; Fatma, Farheen; Amarasinghe, Gaya K.; Mitreva, Makedonka; Bailey, Thomas C.; Clifford, David B.; Khader, Shabaana A.

25 years of Ebola Virus VP35 Research 25年埃博拉病毒VP35研究

Journal of Molecular Biology

IF4.5

2025-07-31

PREAI

Grace Uwase; Daisy W. Leung; Gaya K. Amarasinghe

Single-cell image-based screens identify host regulators of Ebola virus infection dynamics 单细胞图像筛选鉴定宿主调控埃博拉病毒感染动态的因子

Nature Microbiology

IF19.4

2025-07-24

PREAI

Rebecca J. Carlson; J. J. Patten; George Stefanakis; Brian Y. Soong; Adityanarayanan Radhakrishnan; Avtar Singh; Naveen Thakur; Kathleen C. F. Sheehan; Gaya K. Amarasinghe; Nir Hacohen; Christopher F. Basler; Daisy W. Leung; Caroline Uhler; Robert A. Davey; Paul C. Blainey

Molecular basis for human respiratory syncytial virus transcriptional regulator NS1 interactions with MED25 人类呼吸道合胞病毒转录调节因子NS1与MED25相互作用的分子基础

NATURE COMMUNICATIONS

IF15.7

2025-03-25

OAAI

Kalita, Parismita; Khatavkar, Oam; Uwase, Grace; Korshunova, Yulia; Hu, Yuying; Wagner, Nicole D.; Xu, Jian; Pan, Jiehong; Nix, Jay C.; Gross, Michael L.; Brody, Steven L.; Borek, Dominika; Amarasinghe, Gaya K.; Payton, Jacqueline E.; Leung, Daisy W.

Enhanced Staphylococcus aureus protection by uncoupling of the α-toxin-ADAM10 interaction during murine neonatal vaccination

NATURE COMMUNICATIONS

IF15.7

2024-10-08

OAAI

Tomaszewski, Kelly L.; Blanchard, Meagan; Olaniyi, Reuben; Brenton, Hannah R.; Hayes, Samantha; Fatma, Farheen; Amarasinghe, Gaya K.; Cho, Byoung-Kyu; Goo, Young Ah; Dedent, Andrea C.; Fritz, Stephanie A.; Wardenburg, Juliane Bubeck

Serological assays for differentiating natural COVID-19 infection from vaccine induced immunity

JOURNAL OF CLINICAL VIROLOGY

IF3.4

2024-02-01

OAAI

Cheng, Samuel M. S.; Lau, Jonathan J.; Tsang, Leo C. H.; Leung, Kathy; Lee, Cheuk Kwong; Hachim, Asmaa; Kavian, Niloufar; Chaothai, Sara; Wong, Ricky W. K.; Yu, Jennifer K. M.; Chai, Zacary Y. H.; Mori, Masashi; Wu, Chao; Yiu, Karen; Hui, David S. C.; Amarasinghe, Gaya K.; Poon, Leo L. M.; Wu, Joseph T.; Valkenburg, Sophie A.; Peiris, Malik

Viral Targeting of Importin Alpha-Mediated Nuclear Import to Block Innate Immunity

CELLS

IF5.2

2023-12-29

OAAI

Vogel, Olivia A.; Forwood, Jade K.; Leung, Daisy W.; Amarasinghe, Gaya K.; Basler, Christopher F.

A Flexible, Quantitative Plasmonic-Fluor Lateral Flow Assay for the Rapid Detection of Orthoebolavirus zairense and Orthoebolavirus sudanense

ACS INFECTIOUS DISEASES

IF3.8

2023-12-04

OAAI

Qavi, Abraham J.; Jiang, Qisheng; Aman, M. Javad; Vu, Hong; Zetlin, Larry; Dye, John M.; Froude, Jeffrey W.; Leung, Daisy W.; Holtsberg, Frederick; Crick, Scott L.; Amarasinghe, Gaya K.

Real-world COVID-19 vaccine effectiveness against the Omicron BA.2 variant in a SARS-CoV-2 infection-naive population (vol 29, pg 348, 2023)

NATURE MEDICINE

IF50

2023-10-24

OAAI

Lau, Jonathan J.; Cheng, Samuel M. S.; Leung, Kathy; Lee, Cheuk Kwong; Hachim, Asmaa; Tsang, Leo C. H.; Yam, Kenny W. H.; Chaothai, Sara; Kwan, Kelvin K. H.; Chai, Zacary Y. H.; Lo, Tiffany H. K.; Mori, Masashi; Wu, Chao; Valkenburg, Sophie A.; Amarasinghe, Gaya K.; Lau, Eric H. Y.; Hui, David S. C.; Leung, Gabriel M.; Peiris, Malik; Wu, Joseph T.

Elevated Level of Circulating but Not Urine S100A8/A9 Identifies Poor COVID-19 Outcomes 循环而非尿液S100A8/A9水平升高可识别不良新型冠状病毒肺炎结果

ACS INFECTIOUS DISEASES

IF3.8

2023-10-03

OAAI

Mellett, Leah; Amarasinghe, Gaya; Farnsworth, Christopher W.; Khader, Shabaana A.

Lrp1 is essential for lethal Rift Valley fever hepatic disease in mice

SCIENCE ADVANCES

IF12.5

2023-07-14

OAAI

Schwarz, Madeline M.; Ganaie, Safder S.; Feng, Annie; Brown, Griffin; Yangdon, Tenzin; White, J. Michael; Hoehl, Ryan M.; McMillen, Cynthia M.; Rush, Rachael E.; Connors, Kaleigh A.; Cui, Xiaoxia; Leung, Daisy W.; Egawa, Takeshi; Amarasinghe, Gaya K.; Hartman, Amy L.

Ebolavirus Species-Specific Interferon Antagonism Mediated by VP24

VIRUSES-BASEL

IF3.5

2023-04-28

OAAI

Ramanathan, Palaniappan; Tigabu, Bersabeh; Santos, Rodrigo I.; Ilinykh, Philipp A.; Kuzmina, Natalia; Vogel, Olivia A.; Thakur, Naveen; Ahmed, Hamza; Wu, Chao; Amarasinghe, Gaya K.; Basler, Christopher F.; Bukreyev, Alexander

Real-world COVID-19 vaccine effectiveness against the Omicron BA.2 variant in a SARS-CoV-2 infection-naive population 在未感染SARS-CoV-2的人群中，针对Omicron BA.2变体的真实新型冠状病毒肺炎疫苗有效性

NATURE MEDICINE

IF50

2023-01-18

112

OAAI

Ubiquitin variants potently inhibit SARS-CoV-2 PLpro and viral replication via a novel site distal to the protease active site

PLOS PATHOGENS

IF4.9

2022-12-22

OAAI

van Vliet, Vera J. E.; Huynh, Nhan; Pala, Judith; Patel, Ankoor; Singer, Alex; Slater, Cole; Chung, Jacky; van Huizen, Mariska; Teyra, Joan; Miersch, Shane; Luu, Gia-Khanh; Ye, Wei; Sharma, Nitin; Ganaie, Safder S.; Russell, Raquel; Chen, Chao; Maynard, Mindy; Amarasinghe, Gaya K.; Mark, Brian L.; Kikkert, Marjolein; Sidhu, Sachdev S.

Rift Valley Fever Virus Infects the Posterior Segment of the Eye and Induces Inflammation in a Rat Model of Ocular Disease

JOURNAL OF VIROLOGY

IF3.8

2022-10-26

OAAI

Schwarz, Madeline M.; Connors, Kaleigh A.; Davoli, Katherine A.; McMillen, Cynthia M.; Albe, Joseph R.; Hoehl, Ryan M.; Demers, Matthew J.; Ganaie, Safder S.; Price, David A.; Leung, Daisy W.; Amarasinghe, Gaya K.; McElroy, Anita K.; Reed, Douglas S.; Hartman, Amy L.

Oropouche orthobunyavirus infection is mediated by the cellular host factor Lrp1

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-08-08

OAAI

Schwarz, Madeline M.; Price, David A.; Ganaie, Safder S.; Feng, Annie; Mishra, Nawneet; Hoehl, Ryan M.; Fatma, Farheen; Stubbs, Sarah H.; Whelan, Sean P. J.; Cui, Xiaoxia; Egawa, Takeshi; Leung, Daisy W.; Amarasinghe, Gaya K.; Hartman, Amy L.

Plasmonic Fluor-Enhanced Antigen Arrays for High-Throughput, Serological Studies of SARS-CoV-2

ACS INFECTIOUS DISEASES

IF3.8

2022-07-22

OAAI

Qavi, Abraham J.; Wu, Chao; Lloyd, Matthew; Zaman, Mohammad Mahabub-Uz; Luan, Jingyi; Ballman, Claire; Leung, Daisy W.; Crick, Scott L.; Farnsworth, Christopher W.; Amarasinghe, Gaya K.

研究方向