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Preclinical in vitro and in vivo evaluation of CD8aß+CD19 CAR iPSCs T cells generated in a TCR signal-independent manner using DLL4/VCAM-coupled microbeads Belew, Muluken S.; Carpenedo, Richard; Pallaoro, Alessia; Hoi, Hiofan; Deyati, Avisek; Kirouac, Daniel C.; Chandrasekaran, Siddarth; Wall, Valerie; Abraham, Libin; Apelu, Sommer; Cadell, Michael H.; AuYeung, Amanda; Subedar, Omar; Martinez, Elisa; Joshi, Shri; Csaszar, Elizabeth; Woodside, Steven; Titus, Emily; Bond, Christopher 分享 收藏
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The engineered CD80 variant fusion therapeutic davoceticept combines checkpoint antagonism with conditional CD28 costimulation for anti-tumor immunity Maurer, Mark F.; Lewis, Katherine E.; Kuijper, Joseph L.; Ardourel, Dan; Gudgeon, Chelsea J.; Chandrasekaran, Siddarth; Mudri, Sherri L.; Kleist, Kayla N.; Navas, Chris; Wolfson, Martin F.; Rixon, Mark W.; Swanson, Ryan; Dillon, Stacey R.; Levin, Steven D.; Kimbung, Yengo Raymond; Akutsu, Masato; Logan, Derek T.; Walse, Bjorn; Swiderek, Kristine M.; Peng, Stanford L. 分享 收藏
Dph3 Enables Aerobic Diphthamide Biosynthesis by Donating One Iron Atom to Transform a [3Fe-4S] to a [4Fe-4S] Cluster in Dph1-Dph2 Zhang, Yugang; Su, Dan; Dzikovski, Boris; Majer, Sean H.; Coleman, Rachael; Chandrasekaran, Siddarth; Fenwick, Michael K.; Crane, Brian R.; Lancaster, Kyle M.; Freed, Jack H.; Lin, Hening 分享 收藏
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ALPN-202 combines checkpoint inhibition with conditional T cell costimulation to overcome T cell suppression by M2c macrophages and improve the durability of engineered T cell anti-tumor responses Maurer, Mark F.; Chandrasekaran, Siddarth; Lewis, Katherine; Mudri, Sherri; Kleist, Kayla; Ahmed-Qadri, Fariha; Gudgeon, Chelsea; Levin, Steven D.; Dillon, Stacey R.; Swiderek, Kristine M.; Peng, Stanford L. 分享 收藏
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HSP90 Inhibitor Encapsulated Photo-Theranostic Nanoparticles for Synergistic Combination Cancer Therapy Lin, Tzu-yin; Guo, Wenchang; Long, Qilai; Ma, Aihong; Liu, Qiangqiang; Zhang, Hongyong; Huang, Yee; Chandrasekaran, Siddarth; Pan, Chongxian; Lam, Kit S.; Li, Yuanpei 分享 收藏
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A physical sciences network characterization of circulating tumor cell aggregate transport King, Michael R.; Phillips, Kevin G.; Mitrugno, Annachiara; Lee, Tae-Rin; de Guillebon, Adelaide M. E.; Chandrasekaran, Siddarth; McGuire, Matthew J.; Carr, Russell T.; Baker-Groberg, Sandra M.; Rigg, Rachel A.; Kolatkar, Anand; Luttgen, Madelyn; Bethel, Kelly; Kuhn, Peter; Decuzzi, Paolo; McCarty, Owen J. T. 分享 收藏
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