Harel Weinstein - Publications, H-index & Citations

Harel Weinstein

Weill Cornell Medicine

81H指数

536论文数

2.5W被引数

收录论文 178

发表时间

Recognition of Specific PIP2-subtype Composition Triggers the Allosteric Control Mechanism for Selective Membrane Targeting of Cargo Loading and Release Functions of the Intracellular Sterol Transporter StarD4 识别特定的PIP2亚型组成触发了内源性固醇转运蛋白StarD4的选择性膜靶向、货物装载和释放功能的别构控制机制。

Journal of Molecular Biology

IF4.5

2025-04-15

OAAI

Hengyi Xie; Harel Weinstein

Increasing the Efficiency of Ensemble Molecular Dynamics Simulations with Termination of Unproductive Trajectories Identified at Runtime 提高在运行时识别并终止无效轨迹的集合分子动力学模拟效率

JOURNAL OF PHYSICAL CHEMISTRY A

IF2.8

2025-02-04

PREAI

Marquez, Jack; Cuendet, Michel A.; Caino-Lores, Silvina; Estrada, Trilce; Deelman, Ewa; Weinstein, Harel; Taufer, Michela

ModeHunter: A Package for the Reductionist Analysis, Animation, and Application of Elastic Biomolecular Motion ModeHunter：一个用于弹性生物分子运动简化分析、动画制作和应用的软件包

JOURNAL OF PHYSICAL CHEMISTRY B

IF2.9

2025-01-10

PREAI

Wriggers, Willy; Alshammari, Maytha; Stember, Joseph N.; Stolzenberg, Sebastian; Metwally, Essam; Auer, Manfred; He, Jing; Weinstein, Harel

A Mechanistic Understanding of the Modes of Ca2+ Ion Binding to the SARS-CoV-1 Fusion Peptide and Their Role in the Dynamics of Host Membrane Penetration

ACS INFECTIOUS DISEASES

IF3.8

2024-01-25

OAAI

Carten, Juliana Debrito; Khelashvili, George; Bidon, Miya K.; Straus, Marco R.; Tang, Tiffany; Jaimes, Javier A.; Whittaker, Gary R.; Weinstein, Harel; Daniel, Susan

Allosterically coupled conformational dynamics in solution prepare the sterol transfer protein StarD4 to release its cargo upon interaction with target membranes

FRONTIERS IN MOLECULAR BIOSCIENCES

IF4

2023-05-18

OAAI

Xie, Hengyi; Weinstein, Harel

A GIPC1-Palmitate Switch Modulates Dopamine Drd3 Receptor Trafficking and Signaling

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-17

OAAI

Arango-Lievano, Margarita; Sensoy, Ozge; Borie, Amelie; Corbani, Maithe; Guillon, Gilles; Sokoloff, Pierre; Weinstein, Harel; Jeanneteau, Freddy

Host protein kinases required for SARS-CoV-2 nucleocapsid phosphorylation and viral replication

SCIENCE SIGNALING

IF6.6

2022-10-25

OAAI

Yaron, Tomer M.; Heaton, Brook E.; Levy, Tyler M.; Johnson, Jared L.; Jordan, Tristan X.; Cohen, Benjamin M.; Kerelsky, Alexander; Lin, Ting-Yu; Liberatore, Katarina M.; Bulaon, Danielle K.; Nest, Samantha J. Van; Koundouros, Nikos; Kastenhuber, Edward R.; Mercadante, Marisa N.; Shobana-Ganesh, Kripa; He, Long; Schwartz, Robert E.; Chen, Shuibing; Weinstein, Harel; Elemento, Olivier; Piskounova, Elena; Nilsson-Payant, Benjamin E.; Lee, Gina; Trimarco, Joseph D.; Burke, Kaitlyn N.; Hamele, Cait E.; Chaparian, Ryan R.; Harding, Alfred T.; Tata, Aleksandra; Zhu, Xinyu; Tata, Purushothama Rao; Smith, Clare M.; Possemato, Anthony P.; Tkachev, Sasha L.; V. Hornbeck, Peter; Beausoleil, Sean A.; Anand, Shankara K.; Aguet, Francois; Getz, Gad; Davidson, Andrew D.; Heesom, Kate; Kavanagh-Williamson, Maia; Matthews, David A.; tenOever, Benjamin R.; Cantley, Lewis C.; Blenis, John; Heaton, Nicholas S.

Dual-Reporter System for Real-Time Monitoring of SARS-CoV-2 Main Protease Activity in Live Cells Enables Identification of an Allosteric Inhibition Path

ACS BIO & MED CHEM AU

IF4.3

2022-10-17

OAAI

Bram, Yaron; Duan, Xiaohua; Nilsson-Payant, Benjamin E.; Chandar, Vasuretha; Wu, Hao; Shore, Derek; Fajardo, Alvaro; Sinha, Saloni; Hassan, Nora; Weinstein, Harel; TenOever, Benjamin R.; Chen, Shuibing; Schwartz, Robert E.

The allosteric mechanism leading to an open-groove lipid conductive state of the TMEM16F scramblase

COMMUNICATIONS BIOLOGY

IF5.1

2022-09-19

OAAI

Khelashvili, George; Kots, Ekaterina; Cheng, Xiaolu; Levine, Michael, V; Weinstein, Harel

Molecular determinants of pH sensing in the proton-activated chloride channel 质子激活的氯离子通道中pH传感的分子决定因素

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-07-25

OAAI

Osei-Owusu, James; Kots, Ekaterina; Ruan, Zheng; Mihaljevic, Ljubica; Chen, Kevin Hong; Tamhaney, Ami; Ye, Xinyu; Lu, Wei; Weinstein, Harel; Qiu, Zhaozhu

The permeation of potassium ions through the lipid scrambling path of the membrane protein nhTMEM16

FRONTIERS IN MOLECULAR BIOSCIENCES

IF4

2022-07-22

OAAI

Cheng, Xiaolu; Khelashvili, George; Weinstein, Harel

Phosphatidylinositol phosphates modulate interactions between the StarD4 sterol trafficking protein and lipid membranes

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2022-07-01

OAAI

Zhang, Xiaoxue; Xie, Hengyi; Iaea, David; Khelashvili, George; Weinstein, Harel; Max, Frederick R.

Simulation of pH-Dependent Conformational Transitions in Membrane Proteins: The CLC-ec1 Cl-/H+ Antiporter

MOLECULES

IF4.6

2021-11-18

OAAI

Kots, Ekaterina; Shore, Derek M.; Weinstein, Harel

A Graphic Encoding Method for Quantitative Classification of Protein Structure and Representation of Conformational Changes

IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS

IF3.4

2021-07-01

OAAI

Carrillo-Cabada, Hector; Benson, Jeremy; Razavi, Asghar M.; Mulligan, Brianna; Cuendet, Michel A.; Weinstein, Harel; Taufer, Michela; Estrada, Trilce

Ligand-Dependent Conformational Transitions in Molecular Dynamics Trajectories of GPCRs Revealed by a New Machine Learning Rare Event Detection Protocol

MOLECULES

IF4.6

2021-05-20

OAAI

Plante, Ambrose; Weinstein, Harel

Ca2+-dependent mechanism of membrane insertion and destabilization by the SARS-CoV-2 fusion peptide

BIOPHYSICAL JOURNAL

IF3.1

2021-03-01

OAAI

Khelashvili, George; Plante, Ambrose; Doktorova, Milka; Weinstein, Harel

A lightweight method for evaluating in situ workflow efficiency

nature computational science

IF3.7

2021-01-01

OAAI

Tu Mai Anh Do; Pottier, Loic; Caino-Lores, Silvina; da Silva, Rafael Ferreira; Cuendet, Michel A.; Weinstein, Harel; Estrada, Trilce; Taufer, Michela; Deelman, Ewa

GPCRmd uncovers the dynamics of the 3D-GPCRome (vol 17, 777, 2020)

NATURE METHODS

IF32.1

2020-07-23

OAAI

Rodriguez-Espigares, Ismael; Torrens-Fontanals, Mariona; Tiemann, Johanna K. S.; Aranda-Garcia, David; Ramirez-Anguita, Juan Manuel; Stepniewski, Tomasz Maciej; Worp, Nathalie; Varela-Rial, Alejandro; Morales-Pastor, Adrian; Medel-Lacruz, Brian; Pandy-Szekeres, Gaspar; Mayol, Eduardo; Giorgino, Toni; Carlsson, Jens; Deupi, Xavier; Filipek, Slawomir; Filizola, Marta; Gomez-Tamayo, Jose Carlos; Gonzalez, Angel; Gutierrez-de-Teran, Hugo; Jimenez-Roses, Mireia; Jespers, Willem; Kapla, Jon; Khelashvili, George; Kolb, Peter; Latek, Dorota; Marti-Solano, Maria; Matricon, Pierre; Matsoukas, Minos-Timotheos; Miszta, Przemyslaw; Olivella, Mireia; Perez-Benito, Laura; Provasi, Davide; Rios, Santiago; R. Torrecillas, Ivan; Sallander, Jessica; Sztyler, Agnieszka; Vasile, Silvana; Weinstein, Harel; Zachariae, Ulrich; Hildebrand, Peter W.; De Fabritiis, Gianni; Sanz, Ferran; Gloriam, David E.; Cordomi, Arnau; Guixa-Gonzalez, Ramon; Selent, Jana

GPCRmd uncovers the dynamics of the 3D-GPCRome

NATURE METHODS

IF32.1

2020-07-13

OAAI

Rodriguez-Espigares, Ismael; Torrens-Fontanals, Mariona; Tiemann, Johanna K. S.; Aranda-Garcia, David; Manuel Ramirez-Anguita, Juan; Stepniewski, Tomasz Maciej; Worp, Nathalie; Varela-Rial, Alejandro; Morales-Pastor, Adrian; Medel-Lacruz, Brian; Pandy-Szekeres, Gaspar; Mayol, Eduardo; Giorgino, Toni; Carlsson, Jens; Deupi, Xavier; Filipek, Slawomir; Filizola, Marta; Carlos Gomez-Tamayo, Jose; Gonzalez, Angel; Gutierrez-de-Teran, Hugo; Jimenez-Roses, Mireia; Jespers, Willem; Kapla, Jon; Khelashvili, George; Kolb, Peter; Latek, Dorota; Marti-Solano, Maria; Matricon, Pierre; Matsoukas, Minos-Timotheos; Miszta, Przemyslaw; Olivella, Mireia; Perez-Benito, Laura; Provasi, Davide; Rios, Santiago; Torrecillas, Ivan R.; Sallander, Jessica; Sztyler, Agnieszka; Vasile, Silvana; Weinstein, Harel; Zachariae, Ulrich; Hildebrand, Peter W.; De Fabritiis, Gianni; Sanz, Ferran; Gloriam, David E.; Cordomi, Arnau; Guixa-Gonzalez, Ramon; Selent, Jana

Use of paramagnetic 19F NMR to monitor domain movement in a glutamate transporter homolog

NATURE CHEMICAL BIOLOGY

IF13.7

2020-06-08

OAAI

Huang, Yun; Wang, Xiaoyu; Lv, Guohua; Razavi, Asghar M.; Huysmans, Gerard H. M.; Weinstein, Harel; Bracken, Clay; Eliezer, David; Boudker, Olga

研究方向